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| 1 | The DNA damage response pathways: at the crossroad of protein modifications显示文摘translational 以后修正在协调细胞的反应到脱氧核糖核酸损坏起一个关键作用。最近的证据建议在多重蛋白质修正之间的相互影响,包括磷酸化, ubiquitylation,乙酰化和 sumoylation,那联合宣传脱氧核糖核酸损坏信号得到房间周期拘捕,脱氧核糖核酸修理, apoptosis 和老朽。特定的 translational 以后修饰词的用途在蛋白质本地化和相互作用上允许时间、空间的控制,并且可以为蛋白质活动的 trans 规章的激活代表一个工具。认出这些特定的修饰词的能力也为信号扩大强调能力,为 genomic 的维护的关键步稳定性和肿瘤预防。这里,我们总结了最近的调查结果在协调脱氧核糖核酸损坏反应加亮 translational 以后修正的复杂性,与脱氧核糖核酸上的强调损坏发信号串联。 | Michael SY Huen Junjie Chen | 2008 | Cell Research2008，18，1： | 7 |
| 2 | The progress in optic nerve regeneration, where are we?显示文摘Optic nerve regeneration is an important area of research. It can be used to treat patients suffering from optic neuropathy and provides insights into the treatment of numerous neurodegenerative diseases. There are many hurdles impeding optic regeneration in mammals. The mammalian central nervous system is non-permissive to regeneration and intrinsically lacks the capacity for axonal regrowth. Any axonal injury also triggers a vicious cycle of apoptosis. Understanding these hurdles provides us with a rough framework to appreciate the essential steps to bring about optic nerve regeneration: enhancing neuronal survival, axon regeneration, remyelination and establishing functional synapses to the original neuronal targets. In this review article, we will go through current potential treatments for optic nerve regeneration, which includes neurotrophic factor provision, inflammatory stimulation, growth inhibition suppression, intracellular signaling modification and modeling of bridging substrates. | Jennifer Wei Huen Shum Kai Liu Kwok-fai So | 2016 | Neural Regeneration Research2016，11，1： | 4 |
| 3 | A rare case of Staphylococcus lugdunensis septicemia associated with myocarditis and atrioventricular block显示文摘Myocarditis is a relatively rare,possibly life-threatening disease characterized by the inflammation of the myocardium.111 The disease pathogenesis is primarily initiated by acute injury and necrosis of cardiomyocytes,leading to an inflammatory response mediated by the immune system that can potentially cause further aggravation of myocardial damage and organ dysfunction.Prognosis in patients with myocarditis depends on the clinical presentation,which ranges from an asymptomatic disease course to the concomitant development of cardiac arrhythmias,heart failure,cardiogenic shock and even the occurrence of death in extreme cases[1]. | Alex Tsz Lai Nganh Sharen Lee Tong LIU Mark Tam Ka Hou Christien Li Michelle Vangi Wong Michael Huen Sum Lam Gary Tse Ishan Lakhani | 2019 | Journal of Geriatric Cardiology2019，16，1： | 2 |
| 4 | MRG15 is a novel PALB2-interaeting :ctor involved in homologous recombin:ion 显示文摘 | Sy S M Huen M S Chen J | 2009 | J Biol Chem2009，284，21： | 1 |
| 5 | 13C NMR analysis and gas uptake measurements of pure and mixed gas hydrates: Development of natural gas transport and storage method using gas hydrate显示文摘 | Yu-Taek Seo Huen Lee | 2003 | Korean Journal of Chemical Engineering2003，，6： | 1 |
| 6 | Effects of age, sex, and persistent organic pollutants on DNA methylation in children 显示文摘 | Huen K Yousefi P Bradman A | 2014 | Environmental and Molecular Mutagenesis2014，55，： | 1 |
| 7 | High-pressure vapor-liquid equilibira for carbon-dioxide +methanol, carbon-dioxide+ethanol, and carbon-dioxide + methanol + ethanol 显示文摘 | Ji H Y Hyun S L Huen L | 1993 | J Chem Eng Data1993，38，： | 1 |
| 8 | Performance evaluation of absorption chiller using LiBr + H2N(CH2)2OH +H2O, LiBr + HO (CH2)3OH + H2O, and LiBr +(HOCH2CH2)2NH + H2O as working fluids显示文摘 | Jin-soo Kim Young Park Huen Lee | 1999 | Applied Thermal Engineering1999，，19： | 1 |
| 9 | Dysregulated mi- mPd',lAs and their predicted targets associated with endometrioid en- tometrial adenocarcinoma in Hong Kong women'显示文摘 | 2HUNG T K CHEUNG T H HUEN N Y | | Int J Cancer0，124，6： | 1 |
| 10 | Tectonic structure across the accretionary and erosional parts of the Japan Trench margin显示文摘 | Von Huene R Klaeschen D Cropp B | | 0，，11： | 1 |
| 11 | Observations at convergent margins concerning sediment subduction, subduction erosion, and the growth of continental crust 显示文摘 | Von Huene R Scholl D W | 1991 | Reviews of Geophysics1991，29，： | 1 |
| 12 | A summary of Cenozoic tectonic history along the IPOD Japan Trench transect显示文摘 | Von Huene R Langseth M Nasu N | | 0，，09： | 1 |
| 13 | Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1显示文摘 | HUEN M S Y HUANG J LEUNG J W C | 2010 | Molecular Cell2010，37，6： | 1 |
| 14 | The fossil reptile-order Saurischia,their development and history显示文摘 | von Huene F | 1932 | Monographs of Geological and Palaeontology1932，1，4： | 1 |
| 15 | Sclerosaurus and its relation with other Cotylosaurian and the Turtles显示文摘 | von Huene F | 1920 | Molecular and General Genetics1920，24，2： | 1 |
| 16 | Dysregulated microRNAs and their predicted targets associated with en- dometrioid endometrial adenocarcinoma in Hong Kong wom- en显示文摘 | Chung T K Cheung T H Huen N Y | 2009 | Int J Cancer2009，124，： | 1 |
| 17 | Vi- tamin D target proteins: Function and regulation显示文摘 | CHRISTAKOS S BARLETTA F HUENING M | 2003 | J Cell Biochem2003，88，2： | 1 |
| 18 | Calbindin-D28k is expressed in osteoblastic cells and suppresses their apoptosis by inhibiting caspase-3 activity 显示文摘 | Bellido T Huening M Raval-Pandya M | 2000 | Journal of Biological Chemistry2000，275，26： | 1 |
| 19 | Ocean Drilling Program Leg 112, Peru continental margin: Part 2, Sedimentary history and diagenesis in a coastal upwelling environment显示文摘 | Suess E van Huene R | 1988 | Geology1988，16，10： | 1 |
| 20 | Tsunamigenic slope failure along the Middle America Trench in two tectonic settings显示文摘 | Von Huene R Ranero C R Watts P | 2004 | Marine Geology2004，203，： | 1 |
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