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296篇 您的检索式:作者名="Hubert S"
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1MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC.Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier 2014World Journal of Gastroenterology2014,20,32:4
2Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial显示文摘Harry LA Janssen Monika van Zonneveld Hakan Senturk Stefan Zeuzem Ulus S Akarca Yilmaz Cakaloglu Christopher Simon Thomas MK So Guido Gerken Robert A de Man Hubert GM Niesters Pieter Zondervan Bettina Hansen Solko W Schalm 2005The Lancet . 2005 (9454)2005,,:2
3Initial experience with successful totally robotic laparoscopic cystoprostatectomy and ileal conduit construction in tet-raplegic patients:report of two cases显示文摘Hubert J Chammas M Larre S 2006Journal of Endocrinology2006,,02:2
4Effects of concomitant verbal recall on order effects in personality impression formation 显示文摘Anderson N Hubert S 1963Journal of Verbal Learning and Verbal Behavior1963,2,56:1
5Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial显示文摘Harry LA Janssen Monika van Zonneveld Hakan Senturk Stefan Zeuzem Ulus S Akarca Yilmaz Cakaloglu Christopher Simon Thomas MK So Guido Gerken Robert A de Man Hubert GM Niesters Pieter Zondervan Bettina Hansen Solko W Schalm 20052005 (9454)2005,,9454:1
6First pharmacokinetic-pharmacodynamic study in humans with a selective 5-HT4 receptor agonist显示文摘Appel S Kumle A Hubert M 1997Clin Pharmacol1997,37,3:1
7Effects of plyometric training on maximal power output and jumping ability显示文摘HUBERT M TOMASZ S 0,,01:1
8How Does Insertion in Global Value Chains Affect Upgrading in Industrial Clusters显示文摘John H Hubert S 2002Re- gional Studies2002,,3:1
9A scheduling system for the steelmaking-continuous casting process:a case study from the steel-making industry 显示文摘Hubert M Wolfgang H Wemer S 2009International Journal of Production Research2009,47,15:1
10A genetic map for Brassica oleracea based on RFLP markers detected with expressed DNA sequences and mapping of resistance genes to race 2 of Plasmodiophora brassicae (Woronin)显示文摘Landry B S Hubert N Crete R 1992Genome1992,35,3:1
11Forecast of water demand in Weinan City in China using WDF-ANN model显示文摘Liu Junguo Hubert H G S Xu Jianxin 2003Physics and Chemistry of the Earth2003,28,45:1
12Chalcopyrite thin film solar cells by electrodeposition 显示文摘LINCOT D GUILLEMOLESA J F TAUNIER S GUIMARD D SICX-KURDI J CHAUMONT A ROUSSEL O RAMDANI O HUBERT C FAUVARQUE J P BODEREAU N PARISSI L PANHELEUX P FANOUILLERE P NAGHAVI N GRAND P P BENFARAH M MOGENSEN P KERREC O 2004Solar Energy2004,77,:1
13The Raman spectra of the hexagonal and cubic (spinel) forms of Ge《,3》N《,4》:an experimental and theoretical study显示文摘 K Leinenweber H Hubert 2000Solid State Communications2000,114,:1
14High interaction alginate - hyaluronate associations by hyaluronate deacetylation for the preparation of effident biomaterials显示文摘Oerther S Maurin A Payan E Hubert P I.apicque F Presle N etal 0,,:1
15A genetic linkage map of 100 microsatellite markers for the Pacific oyster Crassostrea gigas显示文摘Hedgecock D Hubert S Li G 2002J SheUfish Res2002,21,1:1
16A genetic map for Brassica oleracea based on RFLP markers detected with expressed DNA sequences and mapping of resisance genes to race 2 of Plasmodiophora brassicae (Woronin)显示文摘Landry B S Hubert N Crete R 1992Genome1992,35,:1
17Fast model selection for robust calibration methods 显示文摘ENGELEN S HUBERT M 2005Analytica Chimica Acta2005,544,12:1
18Influence of the muco- sal epithelium microenvironment on Langerhans cells: implica- tions for the development of squamous intraepithelial lesions of the cervix显示文摘Giannini S L Hubert P Doyen J 2002Int J Cancer2002,97,5:1
19Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control 显示文摘Kristina HE Markus M Hubert S 2000Gene2000,260,12:1
20Robust PCA and classification in biosciences显示文摘Hubert M Engelen S 2004Bioinformatics2004,20,11:1
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