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| 1 | The proprotein convertase subtilisin/kexin type 9 geneE670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations显示文摘Background The association of E670G polymorphism in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and serum lipid profiles is inconsistent in dif- ferent ethnic groups.Bai Ku Yao is a special subgroup of the Yao minority in China.The present study was undertaken association of PCSK9 E670G polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations.Methods A total of 649 subjects of Bai Ku Yao and 646 participants of Han Chinese were randomly selected from our previous stratified randomized cluster samples.Genotyping of the PCSK9 E670G polymorphism was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis,and then confirmed by direct sequencing. Results The levels of serum total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and apolipoprotein(Apo) AI were lower in Bai Ku Yao than in Han(P<0.01 for all).The frequency of A and G alleles was 98.00%and 2.00%in Bai Ku Yao,and 95.20%and 4.80%in Han(P<0.01);respectively. The frequency of AA,AG and GG genotypes was 95.99%,4.01%and 0%in Bai Ku Yao,and 91.02%, 8.36%and 0.62%in Han(P<0.01);respectively.There were also significant differences in the genotypic and allelic frequencies between n and the ratio of ApoAI to ApoB in Han Chinese but not in Bai Ku Yao were different between the AA and AG/GG genotypes(P<0.05 for all).The G allele carriers had higher serum HDL-C and higher ApoAI to ApoB ratio than the G allele noncarriers.When serum lipid parameters in Han were analyzed according to sex,the G allele carriers had higher serum HDL and ApoAI levels in males (P<0.05),and lower ApoB level and higher ApoAI to ApoB ratio in females(P<0.05 for all).Multiple linear regression analysis showed that serum HDL-C levels were correlated with genotypes in both ethnic groups(P<0.05 each).Serum lipid parameters were also correlated with sex,age,body massindex,alcohol consumption,cigarette smoking,and blood pressure in both ethnic groups(P<0.05-0.001).Conclusions These results suggest that the PCSK9 E670G polymorphism is mainly associated with some serum lipid parameters in the Han population,both gender show different relations to different serum lipid parameters.The G allele carriers might have higher serum lipid profiles than the G allele noncarriers. ormal LDL-C(≤3.20 mmol/L) and high LDL-C subgroups (> 3.20 mmol/L,P<0.01;respectively) in Bai Ku Yao, and between normal ApoB(≤1.14 g/L) and high ApoB subgroups(> 1.14 g/L,P < 0.01;respectively) in Han. | Lynn Htet Aung,YIN Rui-xing,MIAO Lin,HU Xi-jiang, YAN Ting-ting,CAO Xiao-li,WU Dong-feng,LI Qing,PAN Shang-ling,WU Jin-zhen (Department of Cardiology,Institute of Cardiovascular Diseases, The First Affiliated Hospital,Guangxi Medical University, Nanning 530021,China) | 2011 | 岭南心血管病杂志2011，17，S1： | 9 |
| 2 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 3 | DNA methyl- transferase inhibitor zebularine induces human cholangiocarcino- ma cell death through alteration of DNA methylation status 显示文摘 | Nakamura K Nakabayashi K Htet Aung K | 2015 | PLoS One2015，10，3： | 1 |
| 4 | Lymph Node Harvested in Laparoscopic Versus Open Colorectal Cancer Approaches: A Meta-analysis显示文摘 | Zhenjie Wu Sen Zhang Lynn Htet Htet Aung Jun Ouyang Lu Wei | 2012 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2012，，1： | 1 |
| 5 | Impact of formulation parameters on physical characteristics of spray dried nanoemulsions and their reconstitutions显示文摘Nanoemulsion as small droplet dispersion allows them to uniformly deposit on substrates,increases the rate of bioavailability,absorption and has a better uptake.Although it is generally accepted that nanoemulsions are stable for years,Oswald ripening which can damage nanoemulsion has been reported[1].In this study,converting nanoemulsion as liquid formulation into solid powders was attempted by using spray drying method.The obtained powders were then characterized,reconstituted and compared to the initial nanoemulsion. | Htoo Htet Myat Garnpimol C. Ritthidej | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 1 |
| 6 | The performance of hand posture in front-and back-of-device interaction for mobile computing 显示文摘 | Jacob O Wobbrock Brad A Myers Htet Aung | 2008 | International Journal of Human-computer Studies:(S1071-5819)2008，12，66： | 1 |
| 7 | Is High Homocysteine Level a Risk Factor for Cognitive Decline in Elderly? A Systematic Review, Meta-Analysis, and Meta-Regression显示文摘 | Roger C. M. Ho Mike W. L. Cheung Erin Fu Hlaing H. Win Min Htet Zaw Amanda Ng Anselm Mak | 2011 | American Journal of Geriatric Psychiatry2011，，7： | 1 |
| 8 | Evaluation of in vitro antioxidant, antiglycation and antimicrobial potential of indigenous Myanmar medicinal plants显示文摘Objective: Myanmar has a long history of using medicinal plants for treatment of various diseases. To the best of our knowledge there are no previous reports on antiglycation activities of medicinal plants from Myanmar. Therefore, this study was aimed to evaluate the antioxidant, antiglycation and antimicrobial properties of 20 ethanolic extracts from 17 medicinal plants indigenous to Myanmar.Methods: In vitro scavenging assays of 2,2-diphenyl-1-picrylhydrazyl(DPPH), nitric oxide(NO),superoxide(SO) radicals were used to determine the antioxidant activities. Folin-Ciocalteu's method was performed to determine the total phenolic content. Antiglycation and antimicrobial activities were detected by bovine serum albumin-fluorescent assay and agar well diffusion method.Results: Terminalia chebula Retz.(Fruit), containing the highest total phenolic content, showed high antioxidant activities with inhibition of 77.98% ±0.92%, 88.95% ±2.42%, 88.56% ±1.87% and 70.74% ±2.57% for DPPH, NO, SO assays and antiglycation activity respectively. It also showed the antimicrobial activities against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans with inhibition zone of 19, 18, 17, 25 and 15 mm, respectively. Garcinia mangostana Linn. showed the strongest activities for SO and antiglycation assays with inhibition of 93.68% ±2.63%and 82.37% ±1.78%. Bark of Melia sp. was the best NO radical scavenger with inhibition rate of89.39% ± 0.60%.Conclusion: The results suggest that these plants are potential sources of antioxidants with free radical-scavenging and antiglycation activities and could be useful for decreasing the oxidative stress and glycation end-product formation in glycation-related diseases. | The Su Moe Htet Htet Win Thin Thin Hlaing War War Lwin Zaw Min Htet Khin Mar Mya | 2018 | Journal of Integrative Medicine2018，16，5： | 1 |
| 9 | A new species of Amolops(Anura:Ranidae)from northern Myanmar显示文摘DEAR EDITOR,A new species of the genus Amolops,Amolops putaoensis sp.nov.,is described from northern Myanmar.The new species can be distinguished from its congeners by the following characters:(1)dorsolateral fold distinct;(2)upper-lip stripe white;(3)male body size 37.6-40.2 mm;(4)ground color of dorsal surface brown,flank green,small warts on dorsum. | Yu-Lu Gan Tao Qin Ye htet Lwin Guo-Gang Li Rui-Chang Quan Shuo Liu Guo-Hua Yu | 2020 | Zoological Research2020，41，6： | 1 |
| 10 | Combinatoral materials reseach applied to the development of new surface coatings XV : An investigation of polysiloxane antifoulingc/fouling- release coatings containing qua- ternary ammonium sah groups 显示文摘 | Majumdar P Crowley E Htet M | 2011 | ACS comb Sci2011，13，3： | 1 |
| 11 | 慢性乙型肝炎患者出现原发性胆汁性肝硬化不易察觉的表现: 一例报告显示文摘We are describing an interesting case of two chronic liver diseases in a 48-year-old Chinese woman.While chronic hepatitis B is a common entity in Asia,the patient was later found to have active,asymptomatic primary biliary cirrhosis due to a persistently elevated alkaline phosphatase level after optimal hepatitis B virus DNA suppression on antiviral therapy.This report emphasizes the importance of keeping a high index of suspicion for another potential liver disease process even after a patient has been successfully treated for a primary liver condition.Clinical vigilance,especially in atypical clinical presentations,can result in early accurate diagnosis and prompt treatment. | Asad Javaid Mugilan Poongkunran Felicia D.Allard Win Kyaw Htet Htet Maung Daryl Lau | 2017 | Gastroenterology Report2017，5，2： | 0 |
| 12 | Effect of Conventional and Pulsed TIG Welding on Microstructural and Mechanical Characteristics of AA 6082-T6 Repair Welds显示文摘Repair welding of AA 6082-T6 joints was carried out using ER 4043 filler through the TIG welding process with or without pulsed current.Microstructure and mechanical characteristics of the joints before and after repairing were investigated by examining macrostructure,microstructure,and distributions of porosity in the weld metal(WM),and by hardness,tensile,and bending tests.We observed that the welding current,phase transformations in heat-affected zone(HAZ)and porosity introduced in the WM during welding influence on its mechanical properties in sequence.The experimental results showed that the bead width and penetration as well as size of pores in the joints were mainly influenced by the welding currents.The sound joints were obtained at a welding current of 140 A with or without pulsed current when welding speed and gas flow rate were set at 20 cm·min-1 and 15 L·min-1,respectively.Among them,the decrease in mechanical properties of repair weld(RW)was directly related to the phase transformations in the over-ageing zone due to the double welding thermal cycles and elevated distribution of porosity in the WM.In addition,it was observed that the comparatively smaller grain size and lower porosity in WM of the RW produced by pulsed TIG welding gave a positive effect on its mechanical properties. | NAING Thet Htet MUANGJUNBUREE Prapas | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，4： | 0 |
| 13 | Characterization of Electrical Tree Degradation of Epoxy Resin under Thermal and Temperature Stresses by Photoelastic Effect显示文摘Epoxy resin is widely used in the support,insulation,and packaging components of electrical equipment owing to their excellent insulation,thermal,and mechanical properties.However,epoxy-resin insulation often suffers from thermal and mechanical stresses under extreme environmental conditions and a compact design,which can induce electrical tree degradation and insulation failure in electrical equipment.In this study,the photoelastic method is employed to investigate the thermal-mechanical coupling stress dependence of the electrical treeing behavior of epoxy resin.Typical electrical tree growth morphology and stress distribution were observed using the photoelastic method.The correlation between the tree length and overall accumulated damage with an increase in mechanical stress is determined.The results show that compressive stress retards the growth of electrical trees along the electric field,while tensile stress has accelerating effects.This proves that the presence of thermal stress can induce more severe accumulated damage. | Hein Htet Aung Yuhuai Wang Jin Li Ying Zhang Tatsuo Takada | 2024 | Chinese Journal of Electrical Engineering2024，10，1： | 0 |
| 14 | Survey of feature selection and extraction techniques for stock market prediction显示文摘In stock market forecasting,the identification of critical features that affect the performance of machine learning(ML)models is crucial to achieve accurate stock price predictions.Several review papers in the literature have focused on various ML,statistical,and deep learning-based methods used in stock market forecasting.However,no survey study has explored feature selection and extraction techniques for stock market forecasting.This survey presents a detailed analysis of 32 research works that use a combination of feature study and ML approaches in various stock market applications.We conduct a systematic search for articles in the Scopus and Web of Science databases for the years 2011–2022.We review a variety of feature selection and feature extraction approaches that have been successfully applied in the stock market analyses presented in the articles.We also describe the combination of feature analysis techniques and ML methods and evaluate their performance.Moreover,we present other survey articles,stock market input and output data,and analyses based on various factors.We find that correlation criteria,random forest,principal component analysis,and autoencoder are the most widely used feature selection and extraction techniques with the best prediction accuracy for various stock market applications. | Htet Htet Htun Michael Biehl Nicolai Petkov | 2023 | Financial Innovation2023，9，1： | 0 |
| 15 | 新喀里多尼亚弧菌CGJ02-2中四氢嘧啶合成基因簇ectABC的克隆及其功能鉴定显示文摘研究旨在克隆新的四氢嘧啶合成基因簇,并对其功能进行鉴定,为应用于四氢嘧啶的生产奠定基础。从新喀里多尼亚弧菌CGJ02-2中克隆获得四氢嘧啶合成基因簇ectABC,ectABC与表达载体pBAD连接后转化至大肠杆菌BW25113中,通过L-阿拉伯糖诱导表达。采用SDS-PAGE和液质联用鉴定重组表达蛋白,利用全细胞催化合成四氢嘧啶,通过高分辨质谱鉴定四氢嘧啶,并从天冬氨酸浓度、KCl浓度、温度和pH 4个方面优化催化条件。结果表明,来自新喀里多尼亚弧菌CGJ02-2基因组的ectABC大小为2235 bp。SDS-PAGE显示表达产物中有3个重组蛋白产生,液质联用鉴定表明其分子量分别与ectA、ectB、ectC的理论分子量一致。高分辨质谱分析发现全细胞催化上清中有四氢嘧啶产生。优化后的最适全细胞催化条件为:天冬氨酸浓度100 mmol·L^(-1),KCl浓度100 mmol·L^(-1),温度30℃,pH 7.0,最优条件下产量为1.11 mg·mL^(-1)。研究从弧菌中克隆了四氢嘧啶合成基因簇ectABC,并在大肠杆菌BW25113中实现了异源表达和低盐环境下的四氢嘧啶合成,为大规模发酵生产四氢嘧啶奠定了基础。 | 谭琳 NWE Ni Win Htet 陈偿 PAN Zhiqiang | 2022 | 生物技术进展2022，12，6： | 0 |
| 16 | 波浪推进的水翼船数学模型研究显示文摘This paper discusses mathematical modeling of a ship equipped with energy-saving wing devices.Therewith,the ship is mathematically represented by an elongated hull with high-aspect-ratio wings mounted near its bow and stern.Equations,describing ship motions in regular oncoming waves,are written in the spirit of strip theory with account of inertial and damping influence of energy-saving wing elements with the use of linear expansion of wing-related forces with respect to heave and pitch perturbations.This approach readily yields fast numerical solutions for the propulsion of a ship with wings in waves.The latter solutions are then used as an input for calculation of thrust on wing elements on the basis of classical unsteady foil theories corrected for finite aspect ratio.To evaluate speed of the ship in the modes which allow cruising exclusively by wave power,it is hypothetically assumed that in this case,the wave-generated thrust on the wings equals total drag of the ship-plus-wings system,the latter being defined as a sum of its viscous,wave-making,induced(for wing elements)and added-wave components.Excepting the added-wave term and wings’contributions,the total drag is calculated herein by Holtrop method whereas added-wave resistance is evaluated with Beukelman-Gerritsma formula involving kinematic parameters of heaving and pitching motions of the ship calculated both without and with account of the wings.Also discussed in the paper is a decrease of added wave resistance for a ship with wings as compared to that of ship without wings.Finally,the energy efficiency design index(EEDI)introduced by the International Maritime Organization(IMO)is discussed for representative sea conditions as a measure of ship environmental friendliness. | Kirill V.Rozhdestvensky Zin Min Htet | 2021 | Journal of Marine Science and Application2021，20，4： | 0 |
| 17 | Correction to:A Mathematical Model of a Ship with Wings Propelled by Waves显示文摘The Funding information section was missing from this arti-cle and should have read'The research is partially funded by the Ministry of Science and Higher Education of the Russian Federation as part of World-class Research Center program:Advanced Digital Technologies(contract No.075–15–2020–903 dated 16.11.2020)'.The original article has been corrected. | Kirill V.Rozhdestvensky Zin Min Htet | 2021 | Journal of Marine Science and Application2021，20，4： | 0 |
| 18 | Comparison of Experimental and Theoretical Output Power of Grid Connected Photovoltaic System in Super Mega Factory显示文摘 | Kyaw Kyaw Htet Than Zaw Htwe Wint Wint Kyaw Zeya Oo | 2018 | Journal of Electrical Engineering2018，6，1： | 0 |
| 19 | Chemical analysis of hydroquinone and retinoic acid contents in facial whitening creams显示文摘Hydroquinone is potentially carcinogenic and is known to be a skin and respiratory irritant.Hydroquinone is carcinogenic it has been banned in some countries because of fears of a cancer risk[1,2].Animal studies have shown that topically applied retinoic acid can be photocarcinogenic[3].The aim of this study was qualitative and quantitative determination of hydroquinone and retinoic acid contents in facial whitening creams by colour reaction tests,FT-IR after TLC separation and HPLC. | Aung Myo Htet Ei Ei Thin Mi Mi Saw Soe Win | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 0 |
| 20 | The contribution of a non-governmental organisation’s Community Based Tuberculosis Care Programme to case finding in Myanmar:trend over time显示文摘Background:It is estimated that the standard,passive case finding(PCF)strategy for detecting cases of tuberculosis(TB)in Myanmar has not been successful:26%of cases are missing.Therefore,alternative strategies,such as active case finding(ACF)by community volunteers,have been initiated since 2011.This study aimed to assess the contribution of a Community Based TB Care Programme(CBTC)by local non-government organizations(NGOs)to TB case finding in Myanmar over 4 years.Methods:This was a descriptive study using routine,monitoring data.Original data from the NGOs were sent to a central registry within the National TB Programme and data for this study were extracted from that database.Data from all 84 project townships in five regions and three states in Myanmar were used.The project was launched in 2011.Results:Over time,the number of presumptive TB cases that were referred decreased,except in the Yangon Region,although in some areas,the numbers fluctuated.At the same time,there was a trend for the proportion of cases treated,compared to those referred,that decreased over time(P=0.051).Overall,among 84 townships,the contribution of CBTC to total case detection deceased from 6%to 4%over time(P<0.001).Conclusions:Contrary to expectations and evidence from previous studies in other countries,a concerning reduction in TB case finding by local NGO volunteer networks in several areas in Myanmar was recorded over 4 years.This suggests that measures to support the volunteer network and improve its performance are needed.They may include discussion with local NGOs human resources personnel,incentives for the volunteers,closer supervision of volunteers and improved monitoring and evaluation tools. | Htet Myet Win Maung Saw Saw Petros Isaakidis Mohammed Khogali Anthony Reid Nguyen Binh Hoa Ko Ko Zaw Saw Thein Si Thu Aung | 2017 | Infectious Diseases of Poverty2017，6，1： | 0 |
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