3篇
您的检索式：作者名="Hong Ruijing"
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| 1 | Fast synthesis of monodisperse TiO_2 submicrospheres via a modified sol-gel approach显示文摘Monodisperse titania glycolate submicrospheres were synthesized by a modified sol-gel route, in which ultrasonic treatment was introduced to improve the reaction efficiency. The as-prepared products were characterized by means of Fourier transform infrared spectrum (FT-IR), transmission electron microscopy (TEM), powder X-ray diffraction (XRD), and scanning electron microscopy (SEM). The results indicate that the as-prepared products are titania glycolate submicrospheres with diameters of 230-330 nm. The average particle diameter is estimated to be about 280 nm. Ultrasonic treatment has an important influence on the morphology of the produced titania glycolates. After calcination at 450°C for 2 h, these titania glycolates were completely converted into anatase TiO2. The morphology of TiO2 particles was well reserved during the calcination process except for a reduction of 18% in the average particle size. | WANG Hong'en LI Bo YAN Zaoxuea LU Zhouguang CHENG Ruijing QIAN Donga | 2008 | Rare Metals2008，27，1： | 2 |
| 2 | The effect ofcalcium on the treatment of fresh leachate in an expanded granularsludge bed bioreactor 显示文摘 | Liu Jianyong Hu Jun Zhong Jiangping Luo Jinghuan Zhao Aihua Liu Feng Hong Ruijing Qian Guangren Xu Zhiping | 2011 | Bioresource Technology2011，102，： | 1 |
| 3 | Click CAR-T cell engineering for robustly boosting cell immunotherapy in blood and subcutaneous xenograft tumor显示文摘The adoptive transfer of chimeric antigen receptor-T(CAR-T)cells has shown remarkable clinical responses in hematologic malignancies.However,unsatisfactory curative results and side effects for tumor treatment are still unsolved problems.Herein we develop a click CAR-T cell engineering strategy via cell glycometabolic labeling for robustly boosting their antitumor effects and safety in vivo.Briefly,paired chemical groups(N3/BCN)are separately incorporated into CAR-T cell and tumor via nondestructive intrinsic glycometabolism of exogenous Ac4GalNAz and Ac4ManNBCN,serving as an artificial ligand-receptor.Functional groups anchored on cell surface strengthen the interaction of CAR-T cell and tumor via bioorthogonal click chemistry,further enhancing specific recognition,migration and selective antitumor effects of CAR-T cells.In vivo,click CAR-T cell completely removes lymphoma cells and minimizes off-target toxicity via selective and efficient bioorthogonal targeting in blood cancer.Surprisingly,compared to unlabeled cells,artificial bioorthogonal targeting significantly promotes the accumulation,deep penetration and homing of CAR-T cells into tumor tissues,ultimately improving its curative effect for solid tumor.Click CAR-T cell engineering robustly boosts selective recognition and antitumor capabilities of CAR T cells in vitro and in vivo,thereby holding a great potential for effective clinical cell immunotherapy with avoiding adverse events in patients. | Hong Pan Wenjun Li Ze Chen Yingmei Luo Wei He Mengmeng Wang Xiaofan Tang Huamei He Lanlan Liu Mingbin Zheng Xin Jiang Ting Yin Ruijing Liang Yifan Ma Lintao Cai | 2021 | Bioactive Materials2021，6，4： | 0 |
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