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| 1 | Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis?显示文摘Beside many efforts to improve outcome, sepsis is still one of the most frequent causes of death in critically ill patients. It is the most common condition with high mortality in intensive care units. The complexity of the septic syndrome comprises immunological aspects- i.e.,sepsis induced immunosuppression- but is not restricted to this fact in modern concepts. So far, exact mechanisms and variables determining outcome and mortality stay unclear. Since there is no typical risk profile, early diagnosis and risk stratification remain difficult, which hinders rapid and effective treatment initiation. Due to the heterogeneous nature of sepsis, potential therapy options should be adapted to the individual. Biomarkers like C-reactive protein and procalcitonin are routinely used as complementary tools in clinical decision-making. Beyond the acute phase proteins, a wide bunch of promising substances and non-laboratory tools with potential diagnostic and prognostic value is under intensive investigation. So far, clinical decision just based on biomarker assessment is not yet feasible. However, biomarkers should be considered as a complementary approach. | Dubravka Kojic Benedikt H Siegler Florian Uhle Christoph Lichtenstern Peter P Nawroth Markus A Weigand Stefan Hofer Thorsten Brenner | 2015 | World Journal of Experimental Medicine2015，5，2： | 14 |
| 2 | Hepatic iron concentration does not predict response to standard and pegylated-IFN/ribavirin therapyin patients with chronic hepatitis C显示文摘 | Hofer H Osterreicher C Jessner W | 2004 | J Hepatol2004，40，6： | 1 |
| 3 | Effects of topographic variability on the scaling of plant species richness in gradient dominated landscapes 显示文摘 | Hofer G Wagner H H Herzog F Edwards PJ | 2008 | Ecography2008，31，： | 1 |
| 4 | Narrowband(311-nm) UV-B therapy for small plaque parap~fiasis and early-stage mycosis fungoides显示文摘 | Hofer A Cerroni L Kerl H | 1999 | Arch Dermatol1999，135，11： | 1 |
| 5 | hree year results of proximal tibia fractures treated with the LISS 显示文摘 | Boldin C Fankhauser F Hofer H P | 2006 | Clin Orthop Relat Res2006，445，4： | 1 |
| 6 | Microstructural Aspects on Creep Behaviour of Advanced Power Plant Steels 显示文摘 | Cerjak H Hofer P Schaffernak B | 2000 | Key Eng Mater2000，171，174： | 1 |
| 7 | Centrilobular necrosis in autoimmune hepatitis:a histological feature associated with acute clinical presentation显示文摘 | Hofer H Oesterreicher C Wrba F | 2006 | J Clin Pathol2006，59，3： | 1 |
| 8 | Denervated muscles in humans: limitations and problems of currently used functional electrical stimulation training protocols 显示文摘 | Kern H Hofer C Modlin M | 2002 | Artif Organs2002，26，3： | 1 |
| 9 | Three-year results of proximal tibia fractures treated with LISS显示文摘 | Boldin C Fankhauser F Hofer H P | 2009 | Clin Orthop Relat Res2009，445，4： | 1 |
| 10 | Can the concepts of depression and quality of life be integrated using a time perspective显示文摘 | Moor M Hofer S McGee H | | 0，，： | 1 |
| 11 | Isolation of Brucella microti from mandibular lymph nodes of red foxes, Vulpes vulpes, in lower Austria 显示文摘 | Scholz H C Hofer Eergnaud G | 2009 | Vector Borne Zoonotic Dis2009，9，： | 1 |
| 12 | Centrilobular necrosis in autoim- mune hepatitis : a histological feature associated with acute clinical pres- entation显示文摘 | Hofer H Oesterreicher C Wrba F | 2006 | J Clin Pathol2006，59，3： | 1 |
| 13 | Goal-directed coag- ulation management of major trauma patients using throm- boelastometry(ROTEM)-guided administration of fibrino- gen concentrate and prothrombin complex concentrate 显示文摘 | Schochl H Nienaber U Hofer G | 2010 | Crit Care2010，14，2： | 1 |
| 14 | Isolation of Brucella microti from mandibular lymph nodes of red foxes,Vulpes vulpes,in lower Austria显示文摘 | Scholz H C Hofer E Vergnaud G | 2009 | Vector Borne Zoonotic Dis2009，9，2： | 1 |
| 15 | Overexpression of LEAFY in apple leads to a columnar phenotype with shorter internodes显示文摘 | Flachowsky H Hattasch C Hofer M | 2010 | Planta2010，231，： | 1 |
| 16 | Phenotypic shift of human amniotic epithelial cells in culture is associated with reduced osteogenic differentiation in vitro显示文摘 | G Stadler S Hennerbichler A Lindenmair A Peterbauer K Hofer M van Griensven C Gabriel H Redl S Wolbank | 2008 | Cytotherapy2008，，7： | 1 |
| 17 | Litter fall, litter stocks and decomposition rates in rainforest and agroforestry sites in central Amazon 显示文摘 | MARTIUS C HOFER H MARCOS V B | 2004 | Nutrient Cycling in Agroforestry2004，68，： | 1 |
| 18 | Coordinate regulation of replication and virion sense gene expression in wheat drarf virus显示文摘 | Hofer J M I Dekker E K Reynolds H V | 1992 | Plant Cell1992，4，： | 1 |
| 19 | New unsymmetrieally substituted tetrahydrofurofuran lignans from Artemisia absinthium显示文摘 | Greger H Hofer O | 1980 | Tetrahedron1980，36，： | 1 |
| 20 | Structure and function of fauna communities in Amazonian anthropogenic and natural ecosystems 显示文摘 | HOFER H HANAGARTH W CAREIA M | 2001 | European Journal of Soil Biology2001，37，4： | 1 |
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