|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Treatment strategies for advanced hepatocellular carcinoma:Sorafenib vs hepatic arterial infusion chemotherapy显示文摘Sorafenib is used worldwide as a first-line standardsystemic agent for advanced hepatocellular carcinoma(HCC) on the basis of the results of two large-scale Phase Ⅲ trials. Conversely,hepatic arterial infusion chemotherapy(HAIC) is one of the most recommended treatments in Japan. Although there have been no randomized controlled trials comparing sorafenib with HAIC,several retrospective analyses have shown no significant differences in survival between the two therapies. Outcomes are favorable for HCC patients exhibiting macroscopic vascular invasion when treated with HAIC rather than sorafenib,whereas in HCC patients exhibiting extrahepatic spread or resistance to transcatheter arterial chemoembolization,good outcomes are achieved by treatment with sorafenib rather than HAIC. Additionally,sorafenib is generally used to treat patients with Child-Pugh A,while HAIC is indicated for those with either Child-Pugh A or B. Based on these findings,we reviewed treatment strategies for advanced HCC. We propose that sorafenib might be used as a first-line treatment for advanced HCC patients without macroscopic vascular invasion or Child-Pugh A,while HAIC is recommended for those with macroscopic vascular invasion or Child-Pugh A or B. Additional research is required to determine the best second-line treatment for HAIC non-responders with Child-Pugh B through future clinical trials. | Issei Saeki Takahiro Yamasaki Masaki Maeda Takuro Hisanaga Takuya Iwamoto Koichi Fujisawa Toshihiko Matsumoto Isao Hidaka Yoshio Marumoto Tsuyoshi Ishikawa Naoki Yamamoto Yutaka Suehiro Taro Takami Isao Sakaida | 2018 | World Journal of Hepatology2018，10，9： | 10 |
| 2 | Laterally spreading tumors:Limitations of computed tomography colonography显示文摘AIM:To prospectively investigate the detection rate of laterally spreading tumors(LSTs)of the colorectum by computed tomography(CT)colonography(CTC).METHODS:Patients with LSTs measuring≥20 mm detected during colonoscopy were prospectively enrolled in the study.All patients underwent colonoscopy and subsequent CTC on the same day.CTC was performed using multi-detector CT without contrast in the prone and supine positions.Two radiologists blinded to the existence of LSTs read the virtual endoscopic images as well as 2-D images.LSTs were classified into granular and non-granular types based on colonoscopic appearance.RESULTS:Forty-seven pathologically proven LSTs were evaluated prospectively.Histology included adenomas in 19,mucosal cancers in 19 and T1 cancers in 9.The mean diameter of the LSTs was 35.1 mm.Twenty-eight(60%)LSTs were correctly identified by CTC,and the configuration was similar to the colonoscopic appearance in most cases.Detection rate for the granular type was significantly higher than that for the nongranular type(71%vs 31%,P=0.013).Detection rate of adenomas was significantly lower than mucosal cancers(32%vs 79%,P=0.008)and T1 cancers(32%vs 78%,P=0.042).CONCLUSION:The detection rate of LSTs by CTC,particularly the non-granular type was not acceptable.Practitioners should be aware of the relatively low detection rate when using CTC. | Kazutomo Togashi Kenichi Utano Shigeyoshi Kijima Yosuke Sato Hisanaga Horie Keijirou Sunada Alan T Lefor Hideharu Sugimoto Yoshikazu Yasuda | 2014 | World Journal of Gastroenterology2014，20，46： | 4 |
| 3 | Bone-marrow-derived cells cultured in serum-free medium reduce liver fibrosis and improve liver function in carbon-tetrachloride-treated cirrhotic mice显示文摘 | Takuya Iwamoto Shuji Terai Takuro Hisanaga Taro Takami Naoki Yamamoto Shoko Watanabe Isao Sakaida | 2013 | Cell and Tissue Research2013，，3： | 2 |
| 4 | Antibiotic resistance in Escherichia coli outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA)显示文摘 | George G. Zhanel Tamiko L. Hisanaga Nancy M. Laing Melanie R. DeCorby Kim A. Nichol Barb Weshnoweski Jack Johnson Ayman Noreddin Don E. Low James A. Karlowsky Daryl J. Hoban | 2006 | International Journal of Antimicrobial Agents2006，，6： | 2 |
| 5 | Preoperative T Staging of Colorectal Cancer by CT Colonography显示文摘 | Kenichi Utano M.D. Kazuhiro Endo M.D. Kazutomo Togashi M.D. Ph.D. Junichi Sasaki M.D. Ph.D. Hiroshi J. Kawamura M.D. Ph.D. Hisanaga Horie M.D. Ph.D. Yosikazu Nakamura M.D. Ph.D. Fumio Konishi M.D. Ph.D. Hideharu Sugimoto M.D. Ph.D | 2008 | Diseases of the Colon & Rectum2008，，6： | 2 |
| 6 | Endoscopic papillectomy of minor papillar adenoma associated with pancreas divisum显示文摘Tumors of the minor papilla of the duodenum are quite rare.We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy.A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by upper gastrointestinal endoscopy.Endscopic analysis showed an 18-mm,whitish,sessile mass,located in the duodenum proximal to a normal-appearing major papilla.Endoscopic retrograde pancreatography did not reveal the pancreatic duct.Magnetic resonance cholangiopancreatography showed a lack of the ventral pancreatic duct.We suspected this case was associated with pancreatic divisum;therefore,we performed endoscopic papillectomy of the minor papilla tumor.Subsequently,endoscopic pancreatic stent placement in the minor papilla was done to prevent drainage disturbance.The patient has been asymptomatic without recurrence of tumor or stenosis of the Santorini orifice upon endoscopic examination for the past 2 years. | Akira Kanamori Takashi Kumada Seiki Kiriyama Yasuhiro Sone Makoto Tanikawa Yasuhiro Hisanaga Hidenori Toyoda Hiroki Kawashima Akihiro Itoh Yoshiki Hirooka Hidemi Goto | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 7 | Hepatic portal venous gas after endoscopy in a patient with anastomotic obstruction显示文摘A 72-year-old male underwent a laparoscopic low anterior resection for advanced rectal cancer.A diverting loop ileostomy was constructed due to an anastomotic leak five days postoperatively.Nine months later,colonoscopy performed through the stoma showed complete anastomotic obstruction.The mucosa of the proximal sigmoid colon was atrophic and whitish.Ten days after the colonoscopy,the patient presented in shock with abdominal pain.Abdominal computed tomography scan showed hepatic portal venous gas(HPVG) and a dilated left colon.HPVG induced by obstructive colitis was diagnosed and a transverse colostomy performed emergently.His subsequent hospital course was unremarkable.Rectal anastomosis with diverting ileostomy is often performed in patients with low rectal cancers.In patients with anastomotic obstruction or severe stenosis,colonoscopy through diverting stoma should be avoided.Emergent operation to decompress the obstructed proximal colon is necessary in patients with a blind intestinal loop accompanied by HPVG. | Ai Sadatomo Koji Koinuma Rihito Kanamaru Yasuyuki Miyakura Hisanaga Horie Alan T Lefor Yoshikazu Yasuda | 2015 | World Journal of Gastrointestinal Surgery2015，7，2： | 2 |
| 8 | Serum inter-leukin-6,interleukin-8,hepatocyte growth factor,and ni-tric oxide changes during thoracic surgery显示文摘 | Yamada T Hisanaga M Nakajima Y | 1998 | World J Surg1998，22，8： | 1 |
| 9 | Exercise-induced acute renal failure associated with renal vasoconstriction显示文摘 | Hisanaga S Ueno N Inagaki H | 1999 | Nippon Jinzo Cakkai Shi1999，41，4： | 1 |
| 10 | Photocatalytic degradation of benzene on zeolite-incorporated TiO2film显示文摘 | Teruaki Hisanaga Keiichi Tanaka | 2002 | Journal of Hazardous Materials2002，93，3： | 1 |
| 11 | The alteration of Fas receptor and ligand system in hepatocellular carcino- mas:how do hepatoma cells escape from the host immune surveillance in vivo 显示文摘 | Nagao M Nakajima Y Hisanaga M | 1999 | Hepatology1999，30，2： | 1 |
| 12 | Interleukin-- 6 spill- over in the peripheral circulation increases with the severity of heart failure,and the high plasma level of interleukin--6 is an important prognostic predictor in patients with congestive heart failure显示文摘 | Tsutamoto T Hisanaga T Wada A | 1998 | J Am toll cardiol1998，31，： | 1 |
| 13 | Incidence,outcome,and risk factors of cerebrovascular evevts in patients undergoing maintenance hemodialysis显示文摘 | Kawamura M Fijimoto S Hisanaga S | 1998 | Am J Kidney Dis1998，31，： | 1 |
| 14 | Prognostic value of plasma soluble intercellular adhesion molecule-1 and endothelin-1 concentration in patients with chronic congestive heart failure显示文摘 | Tsutamoto T Hisanaga T Fukai D | 1995 | Am J Cardiol1995，76，： | 1 |
| 15 | Photocatalytic degradation of organophosphorous insecticides in aqueous semiconductor suspensions显示文摘 | Harada K Hisanaga T Tanaka K | 1990 | Water Res1990，24，11： | 1 |
| 16 | The membrane anchored matrix metalloproteinase (MMP) RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer显示文摘 | TAKEUCHI T HISANAGA M NAGAO M | 2004 | Clin Cancer Res2004，16，10： | 1 |
| 17 | The alteration of Fas receptor and ligand system in hepatocellular carcinoma:how do hepatoma cells escape from the host immune surveillance in vivo?显示文摘 | Nagao M Nakajima Y Hisanaga M | 1999 | Hepatology1999，30，2： | 1 |
| 18 | Photocatalyzed degradation of lignin on TiO2显示文摘 | K Tanaka R C R Calanag T Hisanaga | 1999 | Journal of Molecular Catalysis1999，138，23： | 1 |
| 19 | Regulation and role of cyclin-dependent kinase activity in neuronal survival and death显示文摘 | HISANAGA S ENDO R | 2010 | J Neurochem2010，115，6： | 1 |
| 20 | The membrane anchored mat rix metalloproteinase (MMP) RECK in combination wit h MMP29 serves as an informative prognostic indicator for colorectal cancer显示文摘 | Takeuchi T Hisanaga M Nagao M | | 0，，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员