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34篇 您的检索式：作者名="Hirlekar"

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	题名	作者	年代	出处	被引量
1	Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug显示文摘The purpose of the present study was to investigate the interaction of Cinnarizine(CIN)with Hydroxypropyl-β-Cyclodextrin(HPβCD)in the presence of Hydroxy Acids(HA).Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation methods.For the ternary systems,HA were tried in three different concentrations.The interaction in solution phase was studied in detail by the phase solubility method,and the solid phase interactions were characterized by Fourier Transform Infrared(FTIR)spectroscopy,Differential Scanning Calorimetry(DSC),X-Ray Diffractometry(XRD),Scanning Electron Microscopy(SEM)and Proton Nuclear Magnetic Resonance(^1H-NMR).Phase solubility revealed the positive effect of HA on the complexation of CIN with HPβCD.Solid phase characterization confirmed the formation of inclusion complex in the ternary systems.Solubility and dissolution studies illustrated that out of three different concentrations tried,HA were most effective at the 1 M concentration level.Ternary systems were very effective in improving the solubility as well as dissolution profile of CIN than the CIN–HPβCD binary systems.FTIR,^1H-NMR and Molecular docking studies gave some insight at molecular level that actually which part of CIN was interacting with the HPβCD.Molecular docking and free energy calculation even enlighten the role of tartaric acid in increasing solubility of CIN in the ternary system.	Mayank Patel Rajashree Hirlekar	2019	Asian Journal of Pharmaceutical Sciences2019，14，1：	2
2	Pre-operativefasting guidelines:an update显示文摘	Soreide E Eriksson L I Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
3	Preparation and characterization of inclusion complexes of carvedilol with methyl-β-cyclodextrin显示文摘	Rajashree Hirlekar Vilasrao Kadam	2009	Journal of Inclusion Phenomena and Macrocyclic Chemistry (-)2009，，3：	1
4	Preoperative fasting guidelines an update显示文摘	SOREIDE E ERIKSSON LI HIRLEKAR G	2005	Acta Anaesthesiol Scand2005，49，3：	1
5	Preoperative fasting guidelines : an update 显示文摘	Sreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
6	Pre- operative fasting guidelines: an update 显示文摘	SJ2YREIDE E ERIKSSON L I HIRLEKAR G	2005	Acta Anaesthesiol Scand2005，49，8：	1
7	Pre-operative fasting guidelines: an update 显示文摘	Sreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
8	Drug loaded eryth- rocytes: as novel drug delivery system显示文摘	Patel PD Dand N Hirlekar RS	2008	Curr Pharm Des2008，14，1：	1
9	Pre-operative fasting guidelines: an update显示文摘	Sφreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
10	Pre-operative fasting guidelines: an update显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Stand2005，49，：	1
11	Pre-operative fasting guidelines:an update显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
12	Preoperative fasting guidelines : an update 显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
13	Pre-operative fasting guidelines:an update显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
14	Pre -operative fasting guidelines: an update 显示文摘	Sreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，：	1
15	Pre-operative fasting guidelines: an update 显示文摘	Sreide E Erikason L I Hirlekar G	2005	Acta Anaesthesiol Stand2005，49，8：	1
16	Pre -operative fasting guidelines:an update显示文摘	Soreide E Eriksson LI Hirlekar G		0，，08：	1
17	Pre 一 operative fast-ing guidelines: an update 显示文摘	Sreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
18	Preoperative fasting guidelines an update 显示文摘	soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，3：	1
19	Pre-operative fasting guidelines: an update显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesthesiol Scand2005，49，8：	1
20	Preoperative fasting guide-lines:an update显示文摘	Soreide E Eriksson LI Hirlekar G	2005	Acta Anaesth Scand2005，49，8：	1

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