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| 1 | Quality indicators for colonoscopy: Current insights and caveats显示文摘Colonoscopy is the diagnostic modality of choice for investigation of symptoms suspected to be related to the colon and for the detection of polyps and colorectal cancer(CRC). Colonoscopy with removal of detected polyps has been shown to reduce the incidence and mortality of subsequent CRC. In many countries, population screening programs for CRC have been initiated, either by selection of patients for colonoscopy with fecal occult blood testing or by offering colonoscopy directly to average-risk individuals. Several endoscopy societies have formulated quality indicators for colonoscopy. These quality indicators are almost always incorporated as process indicators, rather than outcome measures. This review focuses on the quality indicators bowel preparation, cecal intubation rate, withdrawal time, adenoma detection rate, patient comfort, sedation and complication rate, and discusses the scientific evidence supporting them,as well as their potential shortcomings and issues that need to be addressed. For instance, there is still no clear and generally accepted definition of adequatebowel preparation, no robust scientific evidence is available supporting a cecal intubation rate ≥ 90% and the association between withdrawal time and occurrence of interval cancers has not been clarified. Adenoma detection rate is currently the only quality indicator that has been shown to be associated with interval colorectal cancer, but as an indicator it does not differentiate between subjects with one or more adenoma detected. | Hendrikus JM Pullens Peter D Siersema | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，12： | 7 |
| 2 | Region-Specific Expression of Immunoregulatory Proteins on Microglia in the Healthy CNS显示文摘与中枢神经系统的空间结构高度一致,大部分的中枢神经系统疾病表现为区域性分布。虽然小胶质细胞已被公认在各种中枢神经系统疾病中发挥重要的作用,但是小胶质细胞是否表现为区域特异性目前还不清楚。因此,本研究目的是评估在健康成年小鼠的中枢神经系统的不同区域中小胶质细胞的不同表型。运用体外流式细胞仪分析CD11b,CD40,CD45,CD80,CD86,F4/80,TREM-2b,MHCII,CXCR3,CCR9以及CCR7的表面表达。这些免疫调节标记物大部分均存在于小胶质细胞上并且在表达水平上有明显的区域特异性差异。这些发现在很大程度上证实了在健康成年小鼠中枢神经系统的小胶质细胞中存在着免疫多样性。 | ALEXANDER H.DE HAAS HENDRIKUS W.G.M.BODDEKE KNUT BIBER | 2008 | 神经损伤与功能重建2008，3，3： | 4 |
| 3 | Leaching irrigated saline sandy to sandy loam apedal soils with water of a constant salinity显示文摘 | Johannes Hendrikus Bamard Leon Daniel van Rensburg Alan Thomas Peter Bennie | 2010 | Irrigation Science2010，28，2： | 1 |
| 4 | Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial 显示文摘 | Hendrikus Dubbink Peggy Atmodimedjo Johan Kros | 2015 | Neuro-Oncology2015，0，： | 1 |
| 5 | Short exposure to acetylene to distinguish between nitrifier and denitrifier nitroud oxide production in soil and sediment samples 显示文摘 | Ronald A K Wietse de B Hendrikus J Laanbroek | 1996 | FEMS Microbiology Ecology1996，20，： | 1 |
| 6 | Proforma, ap- proaches for creating computer-interpretable guidelines that facilitate decision support显示文摘 | Paul A Johannes A Hendrikus H | 2004 | Artificial Intelligence in Medi- cine2004，31，1： | 1 |
| 7 | Continuous culture enrichments of ammonia-oxidizing bacteria at low ammonium concentrations显示文摘 | Annette Bollmann Hendrikus J Laanbroek | 2001 | FEMS Microbiology Ecology2001，，3： | 1 |
| 8 | Origin causes and effects of increased nitrite concentration in aquatic environments显示文摘 | Sarah P Hendrikus J L Willy V | 2002 | Reviews in Environmental Science and Biotechnology2002，，1： | 1 |
| 9 | Possibilities for material characterization and FEM simulation of compaction processes of asphalt pavements 显示文摘 | Hendrikus ter Hueme | 2000 | HERON Delft2000，45，3： | 1 |
| 10 | Competition for limiting amounts of oxygen between Nitrosomonas europaea and Nitrobacter winogradskyi grown in mixed continuous cultures显示文摘 | Hendrikus J. Laanbroek Saskia Gerards | 1993 | Archives of Microbiology1993，，5： | 1 |
| 11 | Assessing the expression of chicken anemia virus proteins in plants显示文摘 | Cristiano Lacorte Hendrikus Lohuis Rob Goldbach | 2007 | Virus Research2007，129，2： | 1 |
| 12 | Laparoscopic Fenestration of Liver Cysts in Polycystic Liver Disease Results in a Median Volume Reduction of 12.5%显示文摘 | Loes Keimpema Jelle P. Ruurda Miranda F. Ernst Hendrikus J. A. A. Geffen Joost P. H. Drenth | 2008 | Journal of Gastrointestinal Surgery2008，，3： | 1 |
| 13 | Origin, causes and effects of increased nitrite concentrations in aquatic environments显示文摘 | Sarah Philips Hendrikus J. Laanbroek Willy Verstraete | 2002 | Reviews in Environmental Science and Biotechnology2002，，2： | 1 |
| 14 | Competition for limiting amounts of oxygen between Nitrosomonas europaea and Nitrobacter winogradskyi grown in mixed continuous cultures显示文摘 | Hendrikus J. Laanbroek Saskia Gerards | 1993 | Archives of Microbiology1993，，5： | 1 |
| 15 | Nitrogen as a regulatory factor of methane oxidation in soils and sediments显示文摘 | Paul L.E Bodelier Hendrikus J Laanbroek | 2004 | FEMS Microbiology Ecology2004，，3： | 1 |
| 16 | Nitrogen as a regula-tory factor of methane oxidation in soils and sediments显示文摘 | PAUL L E BODELIER HENDRIKUS J | 2004 | FEMS Mi-crobiology Ecology2004，47，： | 1 |
| 17 | CT-Colonography After Incomplete Colonoscopy: What is the Diagnostic Yield?显示文摘 | Hendrikus J. M. Pullens Maarten S. van Leeuwen Robert J. F. Laheij Frank P. Vleggaar Peter D. Siersema | 2013 | Diseases of the Colon & Rectum2013，，： | 1 |
| 18 | Discrepancies between observed and predicted continuous venovenous hemofiltration removal of antimicrobial agents in critically ill patients and the effects on dosing显示文摘 | Catherine S. C. Bouman Hendrikus J. M. Kan Richard P. Koopmans Johanna C. Korevaar Marcus J. Schultz Margreeth B. Vroom | 2006 | Intensive Care Medicine2006，，12： | 1 |
| 19 | The dynamic status quo of polyhedral silsesquioxane coordination chemistry显示文摘 | Rob W H Rutger A S Hendrikus C A | 2004 | Eur J Inorg Chem2004，2004，4： | 1 |
| 20 | An efficient hybrid,nanostructured,epoxidation catalyst:titanium silsesquioxane-polystyrene copolymer supported on SBA-15显示文摘 | Zhang L Hendrikus C A Gerritsen G | 2006 | Chem Eur2006，13，4： | 1 |
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