|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of liver regeneration after partial hepatectomy and ischemia-reperfusion on expression of growth factor receptors显示文摘瞄准:在肝新生在四不同生长因素受体的表示的时间功课上调查试验性的部分肝切除术和 normothermic ischemia-reperfusion 损坏的效果。这由于在刺激肝新生的生长因素的潜在的治疗学的使用是相关的。方法:为部分肝切除术(PH ) , 80% 肝质量是在 Sprague Dawley 老鼠的 resected。局部缺血和灌注(I/R ) 被门静脉和肝的动脉的吸藏为 15 min 导致。表皮的生长因素受体,肝的生长因素受体,成纤维细胞生长因素受体和瘤坏死因素 receptor-1 被免疫组织化学在损害以后分析直到 72 h。量的 RT-PCR 在最小的受体表示(24 h ) 的时间点被执行。结果:在免疫组织化学, EGFR, HGFR, FGFR 和 TNFR1 与一座山峰在部分肝切除术以后给双性人看了局面的动力学直到 12 h,在 24 h 以后的一个天底和另一弱增加直到 72 h。在肝新生期间,在局部缺血和灌注以后,受体表示更低;在在灌注以后的 24 h 的天底是一样。评估这个天底是否被 mRNA 抄写的缺乏引起,或由于一根柱子翻译规定, RT-PCR 在 24 h 并且与放松肝相比被执行。在每根探针,为受体有特定的 mRNA。EGFR, FGFR 和 TNFR1 mRNA 表示比在放松肝相等或低,在 I/R 以后的 HGFR 表示比在控制强壮。结论:部分至少由于 post-transcriptional 处理,在分析受体的表达式有一个天底在肝损伤以后的 24 h。因此,到在损坏以后的 stimulate 肝新生 24 h 的生长因素的治疗学的使用可能不是成功的。 | P Baier G Wolf-Vorbeck S Hempel UT Hopt E von Dobschuetz | 2006 | World Journal of Gastroenterology2006,12,24: | 8 |
| 2 | 高吸水聚合物(SAP):新型多功能混凝土外加剂 | Viktor Mechtcherine Lukasz Dudziak Arnd-Eike Brüdern Simone Hempel Christof Schrfl 俞琳 | 2012 | 商品混凝土2012,0,5: | 6 |
| 3 | STARR with CONTOUR? TRANSTAR? device for obstructed defecation syndrome: one-year real-world outcomes of the European TRANSTAR registry显示文摘 | G. Ribaric A. D’Hoore G. Schiffhorst E. Hempel | 2014 | International Journal of Colorectal Disease2014,,5: | 3 |
| 4 | In vitro Response of Human Mesenchymal Stromal Cells to Titanium Coated Peek Films and Their Suitability for Magnetic Resonance Imaging显示文摘Medical imaging is an important tool for the post-operative checkup of an accurate position of an implant as well as for monitoring the integration in the adjacent tissue that may influence the success of a medical device.Unfortunately,the possibility to use imaging methods is associated with the implant material and all the established metallic materials for surgery do not show a proper 'imaging compatibility'.The present study is a combined investigation of the in vitro response to human mesenchymal stromal cells(hMSC) and magnetic resonance imaging(MRI) compatibility of the potential material combination polyetheretherketone/titanium(PEEK/Ti) for medical devices.Because of the advantageous imaging properties and the mechanical and chemical stability,PEEK becomes more and more an alternative to common metallic implant materials like titanium or cobalt-chrome.However,PEEK is a bioinert material having a limited ability for direct bone incorporation.Due to its excellent biocompatibility,Ti was chosen as coating material to enhance the cellular response.The result is a combination with advantageous properties:the magnetic susceptibility and elastic modulus close to bone,corrosion resistance and mechanical flexibility of PEEK and the excellent biocompatibility of titanium.The appearance of metal-related artifact was discussed in electrical resistivity and magnetic susceptibility.Therefore,two titanium coatings have been investigated:a complete coating and a structured surface avoiding surface conductivity.To determine the in vitro biocompatibility,the cell responses were assessed in terms of the overall morphology of the hMSC and their cell area distribution,proliferation,osteogenic differentiation and mineral deposition.The cellular stress was evaluated by the prostaglandin E_2 level.The bonded materials both produced no disturbing artifacts in magnetic resonance imaging.Compared to the pure PEEK material,the titanium coated specimens showed an enhanced biocompatibility,which is indicated by a higher cell number,larger activity of the enzyme tissue non-specific alkaline phosphatase and therefore a greater amount of deposited calcium and phosphate.The results on bare PEEK are accompanied with a higher cellular stress level,which is indicated by prostaglandin E_2. | Cindy Elschner Carolin Noack Carolin PreilBler Andreas Krause Ulrich Scheler Ute Hempel | 2015 | Journal of Materials Science & Technology2015,31,5: | 3 |
| 5 | German critical incident reporting system database of prehospital emergency medicine: Analysis of reported communication and medication errors between 2005–2015显示文摘BACKGROUND: Communication failure in prehospital emergency medicine can affect patient safety as it does in other areas of medicine as well. We analyzed the database of the critical incident reporting system for prehospital emergency medicine in Germany retrospectively regarding communication errors.METHODS: Experts of prehospital emergency medicine and risk management screened the database for verbal communication failure, non-verbal communication failure and missing communication at all.RESULTS: Between 2005 and 2015, 845 reports were analyzed, of which 247 reports were considered to be related to communication failure. An arbitrary classifi cation resulted in six different kinds: 1) no acknowledgement of a suggestion; 2) medication error; 3) miscommunication with dispatcher; 4) utterance heard/understood improperly; 5) missing information transfer between two persons; and 6) other communication failure.CONCLUSION: Communication defi cits can lead to critical incidents in prehospital emergency medicine and are a very important aspect in patient safety. | Christian Hohenstein Thomas Fleischmann Peter Rupp Dorothea Hempel Sophia Wilk Johannes Winning | 2016 | World Journal of Emergency Medicine2016,7,2: | 3 |
| 6 | Non-invasive evaluation of hepatic manifestation in Wilson disease with transient elastography, ARFI, and different fibrosis scores显示文摘 | Thomas Karlas Maria Hempel Michael Tr?ltzsch Dominik Huster Peter Günther Hannelore Tenckhoff Joachim M?ssner Thomas Berg Volker Keim Johannes Wiegand | 2012 | Scandinavian Journal of Gastroenterology2012,,11: | 2 |
| 7 | Web3.0时代到来显示文摘从经济状况上说,Web2.0完全是个失败者。像MySpace和Facebook这样的社交网络公司的确拥有忠实的粉丝群,但它们实际上并没在盈利。据预计,2008年MySpace的收入将为6亿美元,这离其母公司新闻集团(News Corp.)给它设定的几十亿美元销售目标相距甚远。 | JESSI HEMPEL | 2009 | 中国计算机用户2009,,6: | 2 |
| 8 | A global movement toward an ecosystem approach to management of marine resources显示文摘 | Sherman K Sissenwine M Christensen V Duda A Hempel G Ibe C Levin S Liuch-Belda D Matishov G McGlade J O'Toole M Switzinger S Serra R Skjoldat H-R Tang Q Thulin J Vandeweerd V Zwanenburg K | | 0,,: | 1 |
| 9 | A novel resorption assay for osteoclast functionality based on an osteoblast-derived native extracellular matrix显示文摘 | Lutter AH Hempel U Wolf-Brandstetter C | | 0,,05: | 1 |
| 10 | Eco- nomics of Disaster Risk, Social Vulnerability, and Mental Health Resilience显示文摘 | Zahran S Peek L Snodgrass J G Weiler S Hempel L | 2011 | Risk Analysis2011,31,7: | 1 |
| 11 | Delineation of temporal bone anatomy:feasibility of low-dose 64-row CT in regard to image quality 显示文摘 | Lutz J Jager V Hempel MJ | 2007 | Eur Radiol2007,17,10: | 1 |
| 12 | The type Ⅲ transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer显示文摘 | Turley R S Finger E C Hempel N | 2007 | Cancer Res2007,67,3: | 1 |
| 13 | Preparative and analytical separation of the Zopiclone enantiomers and determination of their affinity to the benzodiazepine receptor binding site 显示文摘 | Georg Hempel Walter E Muller | 1993 | Chirality1993,5,: | 1 |
| 14 | Measurement of local phase hold-ups in a two- and three-phase bubble column显示文摘 | Dziallas H Michele V Hempel D C | 2000 | Chemical Engineering and Technology2000,23,10: | 1 |
| 15 | Divergint effects of interleukin10 on cytokine production by mononuclear phagocytes and endothelial cells显示文摘 | Sironi M Hempel L | 1993 | Eur J Immunol1993,23,: | 1 |
| 16 | Quantitative analysis of specific Thl/Th2 helper cell responses and IgG subtype antibodies in in- terferon-alpha-treated patients with chronic hepatitis C 显示文摘 | Hempel G Galle PR Lohr HF | 2001 | J Med Virol2001,64,3: | 1 |
| 17 | The clinical and structural long-term results of open repair of massive tears of the rotator cuff显示文摘 | ZUMSTEIN M A JOST B HEMPEL J | 2008 | J Bone Joint Surg Am2008,90,: | 1 |
| 18 | Transforming growth factor-beta1 induces activation of Ras,Raf-1,MEK and MAPK in rat hepatic stellate cells显示文摘 | Hempel U Krautwald S | 1997 | FEBS Lett1997,403,1: | 1 |
| 19 | Studies in the Logic of Conformation ( 1 ) 显示文摘 | C G Hempel | 1945 | Mind1945,,54: | 1 |
| 20 | House buying behavior: an empirical study in cross-cultural buyer behavior显示文摘 | Hempel Jain S C | 1978 | Journal of the American Real Estate and Urban Economics Association1978,,1: | 1 |