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| 1 | Stool therapy may become a preferred treatment of recurrent Clostridium difficile?显示文摘Fecal enemas were first reported to successfully treat life threatening enterocolitis in 1958, but fecal therapy to treat Clostridium difficile (C. difficile ) infection has remained esoteric and not well investigated until recently. In the past few years, systematic reviews of case series and case reports of fecal microbiota transplant for recurrent C. difficile infection have become available and validate use of fecal transplant for C. difficile enterocolitis. Methods of fecal transplant reported in the literature include: nasogastric tube, gastroscope, duodenal tube, colonoscopy, rectal tube, and fecal enemas administered at home; no method has been shown to be superior. A recent randomized study published in New England Journal of Medicine found fecal transplant to be superior to oral vancomycin alone in treatment of recurrent C. difficile enterocolitis. The significance of this trial cannot be underestimated as it lends credibility to the idea of intentionally using microbes to combat disease, providing an alternative to the older paradigm of disease eradication through use of antimicrobials. | Dinesh Vyas Heidi E L'Esperance Arpita Vyas | 2013 | World Journal of Gastroenterology2013，19，29： | 4 |
| 2 | Occult hepatitis B virus infection among Egyptian blood donors显示文摘AIM:To identify blood donors with occult hepatitis B virus(HBV) infection(OBI) to promote safe blood donation.METHODS:Descriptive cross sectional study was conducted on 3167 blood donors negative for hepatitis B surface antigen(HBsAg),hepatitis C antibody(HCV Ab) and human immunodeficiency virus Ab.They were subjected to the detection of alanine aminotransferase(ALT) and aspartate transaminase(AST) and screening for anti-HBV core antibodies(total) by two different techniques;[Monoliza antibodies to hepatitis B core(Anti-HBc) Plus-Bio-Rad] and(ARC-HBc total-ABBOT).Positive samples were subjected to quantitative detection of antibodies to hepatitis B surface(anti-HBs)(ETI-AB-AUK-3,Dia Sorin-Italy).Serum anti-HBs titers > 10 IU/L was considered positive.Quantitative HBV DNA by real time polymerase chain reaction(PCR)(QIAGEN-Germany) with 3.8 IU/mL detection limit was estimated for blood units with negative serum anti-HBs and also for 32 whose anti-HBs serum titers were > 1000 IU/L.Also,265 recipients were included,34 of whom were followed up for 3-6 mo.Recipients were investigated for ALT and AST,HBV serological markers:HBsAg(ETI-MAK-4,Dia Sorin-Italy),anti-HBc,quantitative detection of anti-HBs and HBV-DNA.RESULTS:525/3167(16.6%) of blood units were positive for total anti-HBc,64% of those were antiHBs positive.Confirmation by ARCHITECT anti-HBc assay were carried out for 498/525 anti-HBc positive samples,where 451(90.6%) confirmed positive.Reactivity for anti-HBc was considered confirmed only if two positive results were obtained for each sample,giving an overall prevalence of 451/3167(14.2%) for total anti-HBc.HBV DNA was quantified by real time PCR in 52/303(17.2%) of anti-HBc positive blood donors(viral load range:5 to 3.5 x 105 IU/mL) with a median of 200 IU/mL(mean:1.8 x 104 ± 5.1 x 104 IU/mL).AntiHBc was the only marker in 68.6% of donors.Univariate and multivariate logistic analysis for identifying risk factors associated with anti-HBc and HBV-DNA positivity among blood donors showed that age above thirty and marriage were the most significant risk factors for prediction of anti-HBc positivity with AOR 1.8(1.4-2.4) and 1.4(1.0-1.9) respectively.Other risk factors as gender,history of blood transfusion,diabetes mellitus,frequent injections,tattooing,previous surgery,hospitalization,Bilharziasis or positive family history of HBV or HCV infections were not found to be associated with positive anti-HBc antibodies.Among anti-HBc positive blood donors,age below thirty was the most significant risk factor for prediction of HBV-DNA positivity with AOR 3.8(1.8-7.9).According to HBV-DNA concentration,positive samples were divided in two groups;group one with HBV-DNA ≥ 200 IU/mL(n = 27) and group two with HBV-DNA < 200 IU/mL(n = 26).No significant difference was detected between both groups as regards mean age,gender,liver enzymes or HBV markers.Serological profiles of all followed up blood recipients showed that,all were negative for the studied HBV markers.Also,HBV DNA was not detected among studied recipients,none developed post-transfusion hepatitis(PTH) and the clinical outcome was good.CONCLUSION:OBI is prevalent among blood donors.Nucleic acid amplification/HBV anti core screening should be considered for high risk recipients to eliminate risk of unsafe blood donation. | Zeinab N Said Manal H El Sayed Iman I Salama Enas K Aboel-Magd Magda H Mahmoud Maged El Setouhy Faten Mouftah Manal B Azzab Heidi Goubran Amal Bassili Gamal E Esmat | 2013 | World Journal of Hepatology2013，5，2： | 4 |
| 3 | Negative Inteference in Cardiac Troponin Ⅰ Immunoassays by Circulating Troponin Autoantibodies 显示文摘 | Susann E Heidi H | 2005 | Clinical Chemistry2005，51，： | 1 |
| 4 | Simultaneous Determination of Residues of Chloramphenicol, Florfenicol, Florfenicol Amine, and Thiamphenicol in Shrimp tissue by Chromatography with Electron Capture Detection 显示文摘 | Alien P Pfenning Jose E Roybal Heidi S Rupp | 2000 | Journal of AOAC International2000，83，1： | 1 |
| 5 | The Scholarship of Teaching and Learning: A Special Niche for Faculty at Comprehensive Universities 显示文摘 | Bruce B Henderson Heidi E | 2007 | Research in Higher Educa- tion2007，，5： | 1 |
| 6 | Properties of yttria-aluminoborate glasses显示文摘 | Rutz Heidi L Day Delbert E Spencer Charles F Jr | 1990 | J Am Ceram Soe1990，73，6： | 1 |
| 7 | Risk factor for autism: Perinatal factors, parental psychiatric history, and socioeconomic status显示文摘 | Heidi J L William W E Kreesten M M | 2005 | Am J Epidemiol2005，161，10： | 1 |
| 8 | On industrial knowl- edge bases, commercial opportunities and global innova- tion network linkages显示文摘 | Sverre J H Heidi W A Brend E | 2014 | Research Policy2014，43，： | 1 |
| 9 | Delay in disclosure of childhood rape: results from a national survey显示文摘 | Daniel W Smith Elizabeth J Letourneau Benjamin E Saunders Dean G Kilpatrick Heidi S Resnick Connie L Best | 2000 | Child Abuse & Neglect2000，，2： | 1 |
| 10 | Subjective Well-Being:Three Decades of Progress 显示文摘 | Diener Ed Eunkook M Suh Richard E Lucas & Heidi L Smith | 1999 | Psychological Bulletin1999，125，2： | 1 |
| 11 | Collaborative testing enhances student learning显示文摘 | SUMANGALA P HEIDI L STEPHEN E | 2002 | Adv Physiol Educ2002，26，14： | 1 |
| 12 | The toll-like receptor 4 - antagonist eritoran reduces murine cardiac hypertrophy 显示文摘 | Heidi E Carolyn W Stefan E | 2011 | Eu- ropean Journal of Heart Failure2011，1，15： | 1 |
| 13 | On industrial knowledge bases, commercial opportunities and global innovation network linkages显示文摘 | Sverre J H Heidi W A Bernd E | 2014 | Research Policy2014，，43： | 1 |
| 14 | The biosynthesis of adenosylcobalamin (vitamin B12 ) 显示文摘 | Warren MJ Raux E Heidi L | 2002 | Nat Prod Rep2002，19，： | 1 |
| 15 | Simultaneous Determination of Residues of Chloramphenicol,Flodenicol,Florfenicol Amine,and Thiamphenicol in Shrimp Tissue by Chromatography with Electron Capture Detection显示文摘 | Mien P Pfenning Jose E Roybal Heidi S Rupp | 2000 | Journal of AOAC International2000，83，1： | 1 |
| 16 | Chitosan analysis using acid hydrol- ysis and HPLC/UV显示文摘 | Xun Yan Heidi M E | 2012 | Carbohydrate Polymers2012，87，： | 1 |
| 17 | The iron oxidation state of garnet by electron microprobe: Its determination with the flank method combined with major-element analysis显示文摘 | Heidi E H Gerhard P B | 2007 | American Mineralogist2007，92，： | 1 |
| 18 | Combined Modality Therapy Including Intraoperative Electron Irradiation for Locally Recurrent Colorectal Cancer 显示文摘 | Michael GH Robert CM Heidi N e| al | 2011 | Int J Radiat Oncol Biol Phys2011，79，1： | 1 |
| 19 | Endometrial cancer and obesity:Epidemiology,biomarkers,prevention and survivor-ship显示文摘 | Amanda NF Lucybeth NA Heidi E | 2009 | Gynecol Oncol2009，114，01： | 1 |
| 20 | Chitosan Analysis using Acid Hydrolysis and HPLC/UV显示文摘 | Xun Y Heidi M E | | 0，，02： | 1 |
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