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| 1 | Emerging pollutants in the environment:A challenge for water resource management显示文摘A significant number of emerging pollutants(EPs)resulting from point and diffuse pollution is present in the aquatic environment.These are chemicals that are not commonly monitored but have the potential to enter the environment and cause adverse ecological and human health effects.According to the NORMAN network,at least 700 substances categorized into 20 classes,have been identified in the European aquatic environment.In light of their potential impact action is urgently required.In this study,we present a concept that shows the current state of art and challenges for monitoring programs,fate and risk assessment tools and requirements for policies with respect to emerging pollutants as a base for sustainable water resource management.Currently,methods for sampling and analysis are not harmonized,being typically focused on certain EP classes.For a number of known highly hazardous EPs detection limits are too high to allow proper risk assessment.For other EPs such as microplastics method development is in its infancy.Advanced ultra-sensitive instrumental techniques should be used for quantitative determination of prioritized EPs in water,suspended matter,soil and biota.Data on EPs'and their metabolites'properties that determine their fate in the environment are often not available.National surveys on water quality often use different parameters for water quality assessment and often do not include EPs.A harmonized monitoring of surface and groundwater is not yet achieved and urgently required.Specific component integrated into models assessing the fate of EPs in a multi compartment environmental approach are missing and must be developed.The main goal of risk assessment is the overall protection of ecological communities in the aquatic environment and human health.New methods for assessing the cumulative risks from combined exposures to several stressors,including mixtures of EPs in a multi-scale approach are required.A combination of regulations and management measures with respect to use/emissions of EPs into the environment,as well as to their occurrence in the environment are fundamental to reach an efficient water resource management. | Violette Geissen Hans Mol Erwin Klumpp Günter Umlauf Marti Nadal Martine van der Ploeg Sjoerd E.A.T.M.van de Zee Coen J.Ritsema | 2015 | International Soil and Water Conservation Research2015，3，1： | 3 |
| 2 | Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘 | Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han | 2007 | Immunity2007，，1： | 2 |
| 3 | Onshore wind power devdopment in China: Challenges behind a successful story显示文摘 | HAN J MOL A P J LU Y | 2009 | Energy Policy2009，37，8： | 1 |
| 4 | Determination of polar organophosphorus pesticides in vegetables and fruits using liquid chromatography with tandem mass spectrometry: selection of extraction solvent显示文摘 | Mol Hans G J Ruud C J Odile M | 2003 | Journal of Chromatography A2003，1015，： | 1 |
| 5 | Determination of polar organophosphorus pestieides in vegetables and fruits using liquid chromatography with tauden mass spectrometry: selection of extraction solvent 显示文摘 | Hans G J Mol Ruud C J van Dam Steijgcr O M | 2003 | Journal of Chromatorgraphy A2003，1015，12： | 1 |
| 6 | Solar water heaters in China: A new day dawning显示文摘 | Han JY Mol APJ Lu YL | 2010 | Energy Policy2010，，38： | 1 |
| 7 | Current issues involving screening and identification of chemical contaminants in foods by mass spectrometry显示文摘 | Steven J Lehotay Yelena Sapozhnikova Hans G J Mol | 2015 | TrA C Trends in Analytical Chemistry2015，69，： | 1 |
| 8 | Qualitative aspects and validation of a screening method for pesticides in vegetables and fruits based on liquid chromatography coupled to full scan high resolution (Orbitrap) mass spectrometry显示文摘 | Hans G J Mol Paul Zomer Maarten De Koning | 2012 | Analytical & Bioanalytica! Chemistry2012，403，10： | 1 |
| 9 | Onshore Wind Power Development in China:Challenges Behind a Successful Story 显示文摘 | HAN J Y MOL A P J LU Y L | 2009 | Energy Policy2009，37，： | 1 |
| 10 | Solar Water Heaters in China: A New Day Dawning显示文摘 | Han J Y Mol A P Lu Y L | 2010 | Energy Policy2010，38，： | 1 |
| 11 | Modification and re-validation of the ethyl acetate-based multi-residue method for pesticides in produce显示文摘 | Hans G. J. Mol Astrid Rooseboom Ruud Dam Marleen Roding Karin Arondeus Suryati Sunarto | 2007 | Analytical and Bioanalytical Chemistry2007，，6： | 1 |
| 12 | Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘 | Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han | 2007 | Immunity2007，，1： | 1 |
| 13 | RISC - target interaction: cleavage and translational suppression 显示文摘 | Van Den Berg A Mols J Han J | 2008 | Biochim Biophys Acta2008，1779，11： | 1 |
| 14 | Determination of daminozide in apple and apple leaves by liquid chromatography-mass spectrometry显示文摘 | Hans G J Mol Ruud C J Van Dam | 1999 | J Chromatogr A1999，833，： | 1 |
| 15 | Behavioural, saliva cortisol and heart rate responses to different types of stimuli in dogs显示文摘 | Bonne Beerda Matthijs B.H Schilder Jan A.R.A.M van Hooff Hans W de Vries Jan A Mol | 1998 | Applied Animal Behaviour Science1998，，3： | 1 |
| 16 | Cloning of the canine gene encoding transcription factor Pit-1 and its exclusion as candidate gene in a canine model of pituitary dwarfism 显示文摘 | Iram S Lantiga-van Leeuwen Jan A Mol Hans S Kooistra | 2000 | Mammalian Genome2000，11，： | 1 |
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