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| 1 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 2 | miR-330-3p controls cell proliferation by targeting early growth response 2 in non-small-cell lung cancer显示文摘Non-small-cell 肺癌症(NSCLC ) 是最普通的肺癌症之一,并且 microRNAs (miRNAs ) 被报导了在 NSCLC 起必要作用。最近的研究显示了那 miR-330-3p 表情在 NSCLC 样品并且在 NSCLC 大脑转移的纸巾是起来调整的。在这研究, miR-330-3p 表示的起来规定在 NSCLC 和 20 件 NSCLC 耐心的样品被证实。而且, miR-330-3p 在 NSCLC 房间线 A549 和 H23 是过去表示的,并且 miR-330-3p 的提升功能在调整 NSCLC 房间增长和房间周期分发被调查。为了识别潜力,在 NSCLC 指向 miR-330-3p 的基因, miRNA 目标预言数据库被使用。酶活动试金和即时 RT-PCR 分析证实 miR-330-3p 否定地与早生长反应 2 的表示(EGR2 ) 被相关。而且, EGR2 mRNA 为 miR-330-3p 包含二个潜在的有约束力的地点,这也被发现。有 siRNA 的 EGR2 击倒被表明在 NSCLC 房间线作为 miR-330-3p 的在表示上有类似的效果。一起拿,我们的结果证明 EGR2 是 miR-330-3p 的一个目标。 | Xuzhi Liu Hanbing Shi Bo Liu Jianing Li Yaxin Liu Baiquan Yu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，6： | 8 |
| 3 | WAF-Based Chinese Character Recognition for Spam Image Filtering显示文摘We address the problem of filtering image spam, a kind of rapidly spread spam in which the text is embedded into images to defeat text-based spam filter.Particularly, we focus on image spam with Chinese text as 'spam' which is a more challenging task. A popular way to detect image spam is by Optical character recognition(OCR) system, which detects and recognizes the embedded text, then followed by a text classifier that discriminate spam from ham. However, spammers start to obscure image text to prevent OCR system discovering the spam text. To compensate for the shortcomings of OCR system, a novel method which essentially is a keyword reconstruction algorithm based on Word activation force(WAF) model is proposed. It is effective on discovering keywords, hence is benefit for the later classification stage and notably improve the performance of image spam filtering. The experimental results on a personal data set of spam images(publicly available) validate the effectiveness of our approach that outperforms the original OCR system in practical usage with complex background in image spam. | LI Siyuan LI Ruiguang XU Yuan ZHOU Hao YAN Hanbing XU Bin ZHANG Honggang | 2018 | Chinese Journal of Electronics2018，27，5： | 3 |
| 4 | Filtering Chinese Image Spam Using Pseudo-OCR显示文摘For image spam filtering, the Optical character recognition(OCR) based methods often achieve a better performance due to the more complex structure of recognizing corresponding text. However, applying traditional OCR techniques usually introduced shortcomings like the expensive computational cost, vulnerability to image noises and artificial interferences, especially for Chinese image spam filtering. So, by optimizing recognition procedure of traditional OCR, we propose the idea of pseudo-OCR more suitable for Chinese image spam filtering. During which discriminating the potential image spam character features from ham ones is sufficient, instead of recognizing them. What's more, a novel Chinese key-point based character feature specific for pseudo-OCR is also devised and extracted using a carefully designed algorithm, which outperforms classic corner detection methods in finding such key-points. Experiment results show that our proposed system usually has a better performance than traditional OCR based method while maintaining a low false positive rate. | XU Bin LI Ruiguang LIU Yashu YAN Hanbing LI Siyuan ZHANG Honggang | 2015 | Chinese Journal of Electronics2015，24，1： | 2 |
| 5 | Effect of process parameters on the recrystallization and size control of puerarin using the supercritical fluid antisolvent process显示文摘The purpose of this study was to investigate the influence of the supercritical CO2 processing on the particle size and morphology of puerarin crystals. The process parameters included solvents, temperature, pressures, antisolvent times, addition volumes, antisolvent addition rates and solute concentrations. After being processed, the dramatic reduction of the dimensions and the change of the crystal shape were noticed. Decreasing the antisolvent addition rate, increasing the temperature and the addition volume below 50 ml led to a decrease in size. The new crystal of puerarin generated at the optimal conditions was 30.34 μm.The solvent of methanol and the concentration of 60 mg/ml were found to determine the type and degree of crystallinity of particles. These results showed that this process has the potential to produce a drug recrystallization product with newly generated crystal forms and the size of drug particles could be controlled through the tuning of various experimental conditions. | Ying Li Yibin Yu Hanbing Wang Fengguang Zhao | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，2： | 2 |
| 6 | Trust Degree of Web Services and Its Evaluation with Neural Network显示文摘The concept and definition of trust degree of Web service is given. Evaluating trust degree of Web services with the method of neural network from the aspect of trust history sequence is proposed. The principle of the method, applicable neural network structure, neural network constructing, input standardization, training sample constructing, and the procedure of evaluating trust degree of Web services with trained neural network are described. Experiments show that it is feasible and effective to evaluate trust degree of Web Service with neural network. | HUANG Baohua HU Heping LU Zhengding YAO Hanbing LI Ruixuan | 2006 | Wuhan University Journal of Natural Sciences2006，11，5： | 2 |
| 7 | The Application of Somaclonal Variation in Early Maturity,High Yield and High Quality Improvement in Wheat显示文摘Yield characters, maturity and grain protein content of somaclones derived both from immature embryo of cultivar 77(2)-Spring and single-cell culture of cultivar NE7742 in vitro were studied and the wide variation was found. Somaclones with maturity 8 days earlier than or the same as CK NE 7742 (high yield, early maturity and high quality), combining with high quality (grain protein content 15.5% - 18%) and high yield (the same as 7724 or higher) have been found and selected and now multiplied for 8 generations. The results of cultivar comparison trial in 1995 showed that several somaclones (the yields were significantly higher than CK DN120) could be used directly in wheat production. The studies confirmed that somaclonal variation is one of the effective ways for early maturity, high-yielding and high-quality improvement in wheat. | Hu Shanglian, Zeng Hanbing, Li Wenxiong(Wheat Physiol. and Biotech. Lab, Dept. of Agronomy, NEAU, Harbin 150030, PRC) | 1996 | Journal of Northeast Agricultural University(English Edition)1996，3，2： | 2 |
| 8 | Progressive tool failure in high-speed dry milling of Ti-6Al-4V alloy with coated carbide tools显示文摘 | Anhai Li Jun Zhao Hanbing Luo Zhiqiang Pei Zeming Wang | 2012 | The International Journal of Advanced Manufacturing Technology (-)2012，，5： | 1 |
| 9 | Performance of solar powered thermoacoustic engine at different tilted angles显示文摘 | Chao Shen Yaling He Yuguang Li Hanbing Ke Dongwei Zhang Yingwen Liu | 2009 | Applied Thermal Engineering2009，，13： | 1 |
| 10 | Enhanced endosomal escape of dendrigraft poly-L-lysine polymers for the efficient gene therapy of breast cancer显示文摘Dendrimer,such as dendrigraft poly-L-lysine(DGL)polymers,with high surface charge density,well-defined structure,and narrow poly-dispersity is often employed as a gene vector,but its transfection efficiency is still partially inhibited due to poor endosomal escape ability.Herein,we used a surface modification strategy to enhance the endosomal escape ability of DGL polymers,and thus improved its gene transfection efficiency.A library of phenylboronic acid(PBA)modified DGL polymers(PBA-DGLs)was designed to screen efficient small interfering RNA(siRNA)vectors.The lead candidate screened from the library shown a capability of inducing nearly 90% gene silencing in MDA-MB-231 cells.The study of the transfection mechanism revealed that PBA modification not only improves siRNA cellular uptake,but,more importantly,endows DGL polymers the ability of endosomal escape.One of the top candidates from polyplexes was further shielded with hyaluronic acid to construct targeted nanoparticles,and the yielding nanoparticles significantly suppressed the tumor growth in a breast cancer model by effective siRNA delivery.This research provides a general and effective strategy to enhance the endosomal escape and transfection efficiency of dendrimer. | Li Ye Hongmei Liu Xin Fei Ding Ma Xiaozhen He Qianyun Tang Xue Zhao Hanbing Zou Xiaojing Chen Xianming Kong Peifeng Liu | 2022 | Nano Research2022，15，2： | 1 |
| 11 | Effect of initial gravimetric water content and cyclic wetting-drying on soil-water characteristic curves of disintegrated carbonaceous mudstone显示文摘The soil-water characteristic curve(SWCC)is often used to estimate unsaturated soil properties(e.g.strength,permeability,volume change,solute and thermal diffusivity).The SWCC of soil samples is significantly affected by cyclic wetting-drying.To examine how water content and cyclic wetting-drying affect the SWCC of disintegrated carbonaceous mudstone(DCM),SWCC tests were implemented using a pressure-plate apparatus.In addition,SWCC models for DCM considering the initial gravimetric water content and cyclic wetting-drying were developed.The test results showed that the volumetric water content(θ)of the DCM first decreased rapidly and then became stable as matric suction(s)increased.The initial water content affected the SWCC by altering the pore structure of the DCM.For a given number of wetting-drying cycles,the higher the initial water content,the higher the stabilizedθ.At a given s value,θdecreased as the number of wetting-drying cycles increased,which suggests that cyclic wetting-drying reduces the water-holding capacity of DCM.The Gardner model for DCM was constructed considering initial water content and cyclic wetting-drying,and was effective at describing and predicting the SWCC model for DCM. | Ling Zeng Fan Li Jie Liu Qianfeng Gao Hanbing Bian | 2019 | Transportation Safety and Environment2019，1，3： | 1 |
| 12 | Self-aligned Cu–Si core–shell nanowire array as a high-performance anode for Li-ion batteries显示文摘 | Jun Qu Huaqing Li John J. Henry Surendra K. Martha Nancy J. Dudney Hanbing Xu Miaofang Chi Michael J. Lance Shannon M. Mahurin Theodore M. Besmann Sheng Dai | 2011 | Journal of Power Sources2011，，： | 1 |
| 13 | Study on Sampling Technique of Atmospheric Radionuclide显示文摘Atmospheric radionuclide monitoring usually includes two sampling techniques,namely ultra-high volume aerosol samplers to collect atmospheric particles by using filter media,and radioactive noble gas samplers to collect atmospheric noble gas based on adsorption method. Atmospheric sampling techniques have been researched in Northwest Institute of Nuclear Technology since the Comprehensive Nuclear-Test-Ban Treaty( CTBT) was signed in 1996. Several ultra-high volume aerosol samplers and some types of radioactive xenon isotopes samplers had been developed. For the aerosol sampler,the sampling flow is between 450 and 800 m3/h,with the minimum detectable concentration( MDC) of131 I less than5 μBq /m3. For the xenon sampler,the sampling capacity of xenon is more than 4 ml per day,with MDC of133 Xe less than 0. 25 mBq /m3. After the nuclear accident of Fukushima in 2011,monitoring of the atmospheric radionuclide was carried out for 3 months at Xi'an,and part of radionuclide was detected with concentrations higher than their backgrounds in the period,including131 I,134Cs,137 Cs and133Xe. | Wu Shan Liu Longbo Zhang Changyun Tang Hanbing Chen Liyun Wu Yanmin Xie Feng Li Zhiming Shi Quanlin Dang Haijun | 2014 | Meteorological and Environmental Research2014，5，6： | 1 |
| 14 | Progressive tool failure in high-speed dry milling of Ti-6A1-4V alloy with coated carbide tools显示文摘 | Anhai Li Jun Zhao Hanbing Luo | 2012 | Int J Adv Manuf Technol2012，58，5： | 1 |
| 15 | Effect of BaO addition on electric conductivity of xCu/10NiONiFe2O4cermets显示文摘 | HE Hanbing ZHOU Kechao LI Zhiyou | 2008 | Transactions of Nonferrous Metals Society of China2008，18，： | 1 |
| 16 | The interaction between oxidative stress and mast cell activation plays a role in acute lung injuries induced by intestinal ischemia–reperfusion显示文摘 | Weicheng Zhao Xiaoliang Gan Guangjie Su Gao Wanling Shangrong Li Ziqing Hei Chengxiang Yang Hanbing Wang | 2013 | Journal of Surgical Research2013，，： | 1 |
| 17 | Modulation strategy based on mathematical construction for matrix converter extending the input reactive power range显示文摘 | Li Xing Sun Yao Dan Hanbing | 2014 | IEEE Transactions on Industrial Electronics2014，29，2： | 1 |
| 18 | The design of duplexer with TE08 mode dielectric resonator 显示文摘 | Xu Meng Li Hanbing Wang Zhiyong | 2012 | IEEE Global Symposium on Millimeter Waves2012，，2730： | 1 |
| 19 | Study on the seasonal dynamics of zonal vegetation of NDVI/EV! of costal zonal vegetation based on MODIS data: A case study of Spartina altemiflora salt marsh on Jiangsu Coast, China显示文摘 | Li Jialin Zhao Hanbing Yang Xiaoping | 2011 | African Joumal of Agricultural Research2011，6，17： | 1 |
| 20 | The establishment of a new deliverability equation considering threshold pressure gradient显示文摘The flowing mechanism of a low permeability gas reservoir is different from a conventional gas reservoir,especially for that with higher irreducible water saturation the threshold pressure gradient exists. At present,in all the deliverability equation,the additional pressure drop caused by the threshold pressure gradient is viewed as constant,but this method has big error in the practical application. Based on the non-Darcy steady flow equation,the limited integral of the additional pressure drop is solved in this paper and it is realized that the additional pressure drop is not a constant but has something to do with production data,and a new deliverability equation is derived,with the relevant processing method for modified isochronal test data. The new deliverability equation turns out to be practical through onsite application. | Li Lezhong Li Xiangfang He Dongbo Xu Hanbing | 2009 | Engineering Sciences2009，7，3： | 1 |
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