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| 1 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 2 | Secondary cracking of volatile and its avoidance in infrared-heating pyrolysis reactor显示文摘This study aims to compare the pyrolysis behavior of Huadian oil shale in two infrared heating fixed bed reactors with different directions of infrared beam.Our previous work has shown that fast pyrolysis of oil shale conducted in the shallow fixed bed infrared heating reactor(co-current)presented the massive secondary reactions,which lowered the shale oil production(Siramard et al.,2017).Conversely,the cross-current infrared achieved shale oil yields higher than the Fischer Assay oil yield(13.07 wt%of dry basis),such as 117.7%of the Fischer Assay yield at our realized highest heating rate of 7℃/s under a specified pyrolysis temperature of 550℃.The shale oil from the cross-current infrared heating reactor was obviously heavier than the oil obtained from the cocurrent heating reactor.Thus,the infrared cross heating evidently suppressed the secondary reactions toward volatile.Our realized shale oil yield could reach 13.67 wt%or 122.5%of the Fischer Assay yield under reducing pyrolysis pressure of 0.6 atm,indicating that lower pressure is also beneficial to the release of volatile and reduction of the secondary cracking reactions.This work shows essentially that the infrared cross heating provides an effective merge of the advantages from quick heating and minimization of secondary cracking reactions to enable the shale oil yields being higher than the Fischer Assay oil yield. | Somprasong Siramard Jin-Hui Zhan Zhennan Han Shipei Xu Ondřej Mašek Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，3： | 3 |
| 3 | Pyrolysis characteristics of waste tire particles in fixed-bed reactor with internals显示文摘This study investigated the characteristics of pyrolysis for waste tire particles in the newly developed fixed-bed reactor with internals that are a central gas collection channel mounted inside reactor.And a few metallic plates vertically welded on the internal wall of the reactors and extending to the region closing their central gas collection pipe walls.Experiments were conducted in two laboratory fixed bed reactors with or without the internals.The results shown that employing internals produced more light oil at externally heating temperatures above 700℃due to the inhibited secondary reactions in the reactor.The oil from the reactor with internals contained more aliphatic hydrocarbons and fewer aromatic hydrocarbons,leading to its higher H/C atomic ratios as for crude petroleum oil.The char yield was relatively stable for two beds and showed the higher heating values(HHVs)of about 23 MJ/kg.The gaseous product of pyrolysis mainly consisted of H2 and CH4,but the use of internals led to less pyrolysis gas through its promotion of oil production. | Shipei Xu Dengguo Lai Xi Zeng Lijuan Zhang Zhennan Han Jiguang Cheng Rongcheng Wu Ondřej Mašek Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，3： | 3 |
| 4 | Modulation of paclitaxel resistance by annexin IV in human cancer cell lines 显示文摘 | Han EK Tahir SK Cherian SP | 2000 | Br J Cancer2000，83，1： | 1 |
| 5 | Liver transplantation in patients with hepatitis B virus infection:outcome in Asian versus white patients 显示文摘 | Teo EK Han SH Terrault N | 2001 | Hepatology2001，34，1： | 1 |
| 6 | Pharmacokinetic study of mycophenolic acid in Korean kidney transptant patients显示文摘 | Cho EK Han D J Kim SC | 2004 | Clin Pharmacol2004，44，7： | 1 |
| 7 | Transgelin promotes migration and in- vasion of cancer stem cells 显示文摘 | Lee EK Han GY Park HW | 2010 | J Proteome Res2010，9，10： | 1 |
| 8 | Antisense to cyclinD1 inhibits the growth and tumorigenicity of human colon cancer cells显示文摘 | Arber N Doki Y Han EK | 1997 | Cancer Res1997，57，8： | 1 |
| 9 | Antisense to cyclin Dl inhibits the growth and tumorigenicity of human colon cancer cells 显示文摘 | ARBER N DOKI Y HAN EK | 1997 | Cancer Res1997，57，8： | 1 |
| 10 | Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kappaB activation显示文摘 | Kim EK Kwon KB Han MJ | 2007 | Exp Mol Med2007，39，2： | 1 |
| 11 | The relationship betweenproblem-based learning and clinical performance evalua-tions显示文摘 | Oh SA Chung EK Han ER | 2015 | Korean J Med Educ2015，27，3： | 1 |
| 12 | Ginsenoside Rhl Possesses antiallergic and anti-nflammatory activities显示文摘 | Park EK Choo MK Han M J | 2004 | Int Arch Allergy Immunol2004，，133： | 1 |
| 13 | Antiatherosclerotic and anti-insulin resistance effects of adiponectin:basic and clinical studies显示文摘 | Han SH Sakuma I Shin EK | 2009 | Prog Cardiovasc Dis2009，52，2： | 1 |
| 14 | Antisense to cyclinD1 inhibits to growth and tumorigenicity of human colon cancer cells显示文摘 | Doki Y Han EK | 1997 | Cancer Res1997，57，： | 1 |
| 15 | Antiallergic activity of ginseng and its ginsenosides 显示文摘 | Choo MK Park EK Han MJ | 2003 | Planta Med2003，69，6： | 1 |
| 16 | Intrinsic cardiac nerve activity and paroxysmal atrial tachyarrhythmia in ambulatory dogs 显示文摘 | Choi EK Shen M J Han S | 2010 | Cir- culation2010，121，24： | 1 |
| 17 | The natural history and treatment of adrenal myelolipoma显示文摘 | Han M Burnett AL Fishman EK | 1997 | J Urol1997，157，4： | 1 |
| 18 | Modulation of paclitaxel resistance by annexin IV in human cancer lines显示文摘 | Han EK Tahir SK Cherian SP | 2000 | Br J Cancer2000，83，： | 1 |
| 19 | Blocking CHK1 expression induces apoptosis and abrogates the G2 checkpoint mechanism显示文摘 | Luo Y Chen Z Han EK | 2001 | Neoplasia2001，3，5： | 1 |
| 20 | Com-parison of laser in situ keratomileusis flaps created by 3 femto-second lasers and a microkeratome 显示文摘 | AhnH Kim JK Kim CK Han GH Seo KY Kim EK | 2011 | J Cataract Refract5^2011，37，2： | 1 |
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