维普中文期刊产品整合服务
53篇 您的检索式:作者名="Hall CJ"
    题名 作者 年代 出处 被引量
1全球药物滥用的疾病负担:来自2010年全球疾病负担研究显示文摘背景:直到目前还没有研究者系统地估计过全球及区域性的苯丙胺类、大麻、可卡因和阿片类药物依赖的患病率及其造成的疾病负担。我们旨在用伤残损失寿命年(YLDs)、过早死亡损失寿命年(YLLs)和伤残调整寿命年(DALYs)来估计药物依赖的患病率和其造成的疾病负担。方法:采用贝叶斯Meta回归的方法(Dis Mod-MR)对药物依赖的流行病学研究及2010年全球疾病、伤害及危险因素负担研究(GBD 2010)进行了系统综述,估计人群水平的药物依赖患病率。GBD 2010通过代表性社区调查和基于互联网的调查计算出新的失能权重。我们把估计的药物依赖患病率和新的失能权重结合起来估算药物依赖导致的YLDs、YLLs、DALYs和其作为相关疾病危险因素时导致的YLDs、YLLs和DALYs。结果:2010年,药物依赖直接造成了2千万的DALYs(95%UI(不确定区间)1.3-2.54千万),占全球全因DALYs的0.8%(0.6%-1.0%)。世界范围内,相比于其他药物,越来越多的人依赖于阿片类和苯丙胺类药物。阿片类药物依赖直接造成的疾病负担最大(DALYs为920万,95%UI为710-1140万)。在某些地区,药物依赖导致的DALYs所占比例比其他地区高出20倍,收入越高的国家药物依赖造成的负担所占比例也越高。注射吸毒所致HIV感染造成210万的DALYs(95%UI 110-360万),所致HCV感染导致50.2万的DALYs(95%UI 28.6-89.1万)。苯丙胺类药物依赖所致自杀造成85.4万的DALYs(95%UI 29.1-179.1万),阿片类药物依赖所致自杀造成67.1万的DALYs(95%UI 32.9-173.0万),可卡因依赖所致自杀造成32.4万的DALYs(95%UI 10.9-68.2万)。药物依赖导致的疾病负担最高的国家(>650 DALYs/10万人)包括美国,英国,俄罗斯和澳大利亚。结论:药物滥用是造成全球疾病负担的一个重要因素。为减少人群水平的疾病负担,我们需采取有效的措施(比如给予阿片类药物依赖者替代治疗及针具交换等)降低阿片类药物依赖和注射吸毒导致的疾病负担。王同瑜 Degenhardt L Whiteford HA Ferrari AJ Baxter AJ Charlson FJ Hall WD Freedman G Burstein R Johns Engell RE Flaxman A Murray CJ Vos T 2015中国药物依赖性杂志2015,24,6:3
2Hepatic stem cells: a review显示文摘Vessey CJ Hall PM 2001Pathology2001,33,:2
3胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
4Comparison of Nottingham Health Profile (NHP) scores with exercised duration and measures of ischaemia during treadmill exercise testing in patients with coronary artery disease显示文摘Skinner JS Albers CJ Hall RJ 0,,11:1
5Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities 显示文摘Schloss PD Westcott SL Ryabin T Hall JR Hartmann M Hollister EB Lesniewski RA Oakley BB Parks DH Robinson CJ Sahl JW Stres B Thallinger GG Van Horn DJ Weber CF 2009Appl Environ Microbiol2009,75,23:1
6Obesity, hypertension, and chronic kidney disease 显示文摘Hall ME Do CJ Da SA 2014Int J Nephrol Renovasc Dis2014,7,:1
72005 National hospital discharge survey显示文摘DeFrances CJ Hall MJ 2007Adv Data2007,12,385:1
8irukandji syndrome in northern Western Australia: an emerging health problem 显示文摘Macrokanis CJ Hall NL Mein JK 2004Med J Aust2004,181,11:1
9Hepatic stem cells:a review显示文摘Vessey CJ Hall PM 2001Pathology2001,33,2:1
10Human patient simulation is effective for teaching paramedic students endotracheal intu- bation显示文摘Hall RE Plant JR Bands CJ 2005Acad Emerg Med2005,12,9:1
11Hepatic stem cells: a review显示文摘Vessey CJ de la Hall PM 2001Pathology2001,33,:1
12A multicenter,prospec- tive ,randomized, controlled trial of open reduction-internal fixa- tion versus total elbow arthroplasty for displaced intra-articular distal humeral fractures in elderly patients 显示文摘MeKee MD Veillette CJ Hall JA 2009J Shoulder Elbow Surg2009,18,1:1
13Cellular glutathione content,in vitro chemoresponse,and the effect of BSO modulation in samples derived from patients with advanced ovarian cancer显示文摘Lewandowicz GM Britt P Elgie AW Williamson CJ Coley HM Hall AG 2002Gynecol Oncol2002,85,:1
14Human patient simulation is effective for teaching paramedic students endotracheal intubation显示文摘Hall RE Plant JR Bands CJ 0,,09:1
15Inpatient care for septicemia or sepsis:a challenge for patients and hospitals显示文摘Hall MJ Williams SN DeFrances CJ 0,,62:1
16The A to Z of A/C plasmids显示文摘Harmer CJ Hall RM 2015Plasmid2015,80,:1
17Intestinal differentiation in zebrafish requires Cdx1b,a functional equivalent of mammalian Cdx2显示文摘Flores MV Hall CJ Davidson AJ 2008Gastroenterology2008,135,5:1
18The in vitro differentiation of rat neural stem cells into an insulin-expressing phenotype显示文摘Bums CJ Minger SL Hall S 2005Biochem Biophys Res Commun2005,326,3:1
19Clinical and laboratory features of Mycobacterium porcinum显示文摘Wallace RJ Brown-Elliott BA Wilson RW Mann L Hall L Zhang Y Jost KCJr Brown JM Kabani A Schinsky MF Steigerwalt AG Crist CJ Roberts GD BlacNock Z Tsukamura M Silcox V Turenne C 2004J Clin Microbiol2004,42,12:1
20A multicenter, prospective, randomized, controlled trial of open reduction-intemal fixation versus total elbow arthroplasty for displaced intra-articular distal humeral fractures in elderly patients显示文摘McKee MD Veillette CJ Hall JA 2009J Shoulder Elbow Surg2009,18,1:1
返回顶部 每页显示:
共3页 首页 上一页 第1页 下一页 末页 /3 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费