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| 1 | Genetic Diversity and Association Analysis for Salinity Tolerance, Heading Date and Plant Height of Barley Germplasm Using Simple Sequence Repeat Markers显示文摘The objective of this study was to investigate the genetic diversity of barley accessions. Additionally, association trait analysis was conducted for grain yield under salinity, heading date and plant height. For this purpose, 48 barley genotypes were analyzed with 22 microsatellite simple sequence repeat (SSR) markers. Four of the 22 markers (Bmac316, scssr03907, HVM67 and Bmag770) were able to differentiate all barley genotypes. Cluster and principal coordinate analysis allowed a clear grouping between countries from the same region. The genotypes used in this study have been evaluated for agronomic performance in different environments. Conducting association analysis for grain yield under salinity conditions using TASSEL software revealed a close association of the marker Bmag749 (2H, bin 13) in two different environments with common significant alleles (175, 177), whereas the HVHOTR1 marker (2H, bin 3) was only significant in Sakhar_Egypt with alleles size being 158 and 161. Heading date also showed an association with scssr03907 through the common significant specific allele 111 and EBmac0415 markers in three different agro climatic locations, whereas HVCMA, scssr00103 and HVM67 were linked to heading date in the Egyptian environment only. The plant height association analysis revealed significant markers Bmag770 via the significant allele 152 and scssr09398. | Lilia Eleuch Abderrazek Jilal Stefania Grando Salvatore Ceccarelli Maria von Korff Schmising Hisashi Tsujimoto Amara Hajer Abderrazek Daaloul Michael Baum | 2008 | Journal of Integrative Plant Biology2008，50，8： | 5 |
| 2 | Cytokine and apoptosis gene polymorphisms influence the outcome of hepatitis C virus infection显示文摘BACKGROUND:Hepatitis C virus (HCV) infection is thought to be chronic and the factors leading to viral clearance or persistence are poorly understood.This study was undertaken to investigate the possibility of a significant relationship between the spontaneous clearance or the persistence of hepatitis C virus (HCV) infection and cytokine and apoptosis gene polymorphisms in Tunisian patients on hemodialysis.METHODS:Polymorphisms of the genes IL-1 (-889 IL-1α,-511 and +3954 IL-1β,IL-1Ra),IL-18 (-137 and-607),IL-12 (-1188) and Apo1/Fas (-670) were determined by PCR-RFLP,PCR-SSP and PCR-VNTR in 100 healthy blood donors and 100 patients infected with HCV and undergoing hemodialysis.The patients were classified into two groups:G1 consisted of 76 active chronic hepatitis patients (positive for HCV RNA) and G2 consisted of 24 hemodialysed patients who spontaneously eliminated the virus (negative for HCV RNA).RESULTS:The frequency of genotype association [-137GC/-607CA] IL-18 was higher in G2 (41.7%) than in G1 (15.8%) (P=0.008;OR=0.26;95% CI,0.10-0.73).We also found a higher frequency of the AA genotype of the Apo1/Fas gene in G2 (41.6%) than in G1 (17.5%) (P=0.026;OR=3.49;95% CI,1.13-10.69).Adjustment for known covariate factors (age,gender and genotype) confirmed these univariate findings and revealed that the genotype association GC-CA of the (-137 and-607) IL-18 gene and the AA genotype of the Apo1/Fas gene were associated with the clearance of HCV (P=0.041 and 0.017,respectively).CONCLUSION:The two genotypes GC-CA of the (-137 and-607) IL-18 polymorphism and the AA genotype of the Apo1/Fas gene influence the outcome of HCV infection in Tunisian patients on hemodialysis. | Leila Ksiaa Cheikhrouhou Imen Sfar Hajer Aounallah-Skhiri Houda Aouadi Salwa Jendoubi-Ayed Taieb Ben Abdallah Khaled Ayed Yousr Lakhoua-Gorgi | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 4 |
| 3 | Use of clenbuterol hydrochloride (NAB365) a sympathomimetic agent which stimu- lates beta-2 receptors in horses with respiratory disease 显示文摘 | Sasse H H L Hajer R | 1977 | Tijdschrift voor Diergeneeskunde1977，102，21： | 1 |
| 4 | The living institutions of the EU : analysing governance as performance 显示文摘 | Hajer | 2006 | Perspectives on European politics and society2006，7，1： | 1 |
| 5 | Adipose tissue dysfunction in obesity,diabetes,and vascular diseases显示文摘 | Hajer GR van Haeften TW Visseren FL | | 0，，： | 1 |
| 6 | Policy without polity? Policy analysis and the institutional void显示文摘 | Hajer M | 2003 | Policy Sciences2003，36，2： | 1 |
| 7 | Low plasma levels of adiponectin are associated with low risk for future cardiovascular events in patients with clinical evident vascular disease显示文摘 | Hajer G R van der Graaf Y Olijhoek J K | | 0，，04： | 1 |
| 8 | Spatial Planning in the Network Society:Rethinking the Principles of Planning in the Netherlands显示文摘 | Hajer M Zonneveld W | | 0，，03： | 1 |
| 9 | The Effects of Low-Dose Simvastatin and Ezetimibe Compared to High-Dose Simvastatin Alone on Post-Fat Load Endothelial Function in Patients With Metabolic Syndrome: A Randomized Double-Blind Crossover Trial显示文摘 | Jobien K Olijhoek Gideon R Hajer Yolanda van der Graaf Geesje M Dallinga-Thie Frank L J Visseren | 2008 | Journal of Cardiovascular Pharmacology2008，，2： | 1 |
| 10 | Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs simvastatin/ezetimibe combination therapy显示文摘 | WESTERWEEL P E VISSEREN F L HAJER G R | 2008 | Eur Heart J2008，29，22： | 1 |
| 11 | The effects of low-dose simvastatin and ezetimibe compared tohigh-dose simvastatin alone on post-fat load endothelialfunction in patients with metabolic syndrome, a randomizeddouble-blind crossover trial 显示文摘 | OUJHOEK J K HAJER G R VAN DER GRAAFY | 2008 | J Cardiovasc Pharmacol2008，52，2： | 1 |
| 12 | Adipose tissue dysfunction in obesity,diabetes,and vascular diseases显示文摘 | Hajer GR van Haeften TW Visseren FL | | 0，，： | 1 |
| 13 | Adipose tissue dysfunction in obesity,diabetes,and vascular diseases 显示文摘 | HAJER G R VAN HAEFTEN T W VISSEREN FL | 2008 | Eur Heart J-2008，29，24： | 1 |
| 14 | Donald poirier solid- phase chemical synthesis and in vitro biological evaluation of novel 2b-piperazino-(20R) -Sa-pregnane-3a, 20-diol N- derivatives as anti-leukemic agents 显示文摘 | Hajer J Ren~ M Philippe D | 2012 | Steroids2012，77，： | 1 |
| 15 | Spinal deformities in the black-striped pipefish Syngnathus abaster (Pisces, Syngnathidae) from the Tunis North Lake, Tunisia显示文摘 | Hajer Ben Alaya René Galzin Jean-Pierre Quignard Monia Trabelsi | 2010 | Chemosphere2010，，3： | 1 |
| 16 | Adipose tissue dysfunction in obesity, diabetes, and vascular diseases显示文摘 | Hajer GR van Haeften TW Visseren FL | 2008 | Eur HeartJ2008，29，24： | 1 |
| 17 | Spatial Planning in the Network Society - Rethinking the Principles of Planning in the Netherlands显示文摘 | Hajer M Zonneveld W | 2000 | European Planning Studies2000，8，3： | 1 |
| 18 | Low plasma HDL-c,a vascular risk factor in high risk patients independent of LDL-c显示文摘 | Hajer GR Van Der Graaf Y Bots ML | 2009 | Eur J Clin Invest2009，39，8： | 1 |
| 19 | Detection of antibodies against peste des petits ruminants virus in sera of cattle, camels, sheep and goat in Sudan 显示文摘 | Haroun M Hajer I Mukhtar M | 2002 | Vet Res Commun2002，26，7： | 1 |
| 20 | Effect of grafting on watermelon vegetative and root development,production and fruit quality显示文摘 | Aounallah Souheila CHOUKA Hajer JEBAKI | 1999 | Acta Hort1999，，： | 1 |
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