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| 1 | Ythdc2 is an N^6-methyladenosine binding protein that regulates mammalian spermatogenesis显示文摘N 6-methyladenosine (m 6 一) 是在真核细胞的 mRNA 的最普通的内部修正。它动态地被安装并且搬迁,并且充当 mRNA 新陈代谢,包括干细胞 pluripotency 的调整生物过程,房间区别,和精力动态平衡的新层。m 6 A 被选择有约束力的蛋白质认出;YTHDF1 和 YTHDF3 在音乐会工作影响 m 6包含 A 的 mRNAs, YTHDF2 帮助 mRNA 腐烂,和 YTHDC1 影响它的目标的原子处理。YTHDC2 的生物功能, YTH 蛋白质家庭,的最后的成员仍然保持未知。我们报导 YTHDC2 有选择地绑 m 6 在它的一致主题的 A。YTHDC2 提高它的目标的翻译效率并且也减少他们的 mRNA 丰富。Ythdc2 猛烈老鼠是不肥沃的;男性们让显著地更小的睾丸和女性同窝出生的人与那些相比有显著地更小的卵巢。Ythdc2 猛烈老鼠的细菌房间不经过 zygotene 阶段发展,因此,当成熟分裂开始, Ythdc2 是在睾丸的 upregulated。因此, YTHDC2 是 m 6 在精子发生期间起关键作用的 A 绑定蛋白质。 | Phillip J Hsu Yunfei Zhu Honghui Ma Yueshuai Guo Xiaodan Shi Yuanyuan Liu Meijie Qi Zhike Lu Hailing Shi Jianying Wang Yiwei Cheng Guanzheng Luo Qing Dai Mingxi Liu Xuejiang Guo Jiahao Sha Bin Shen Chuan He | 2017 | Cell Research2017,27,9: | 96 |
| 2 | The Sequence of Magmatic-Tectonic Events and Orogenic Processes of the Yanshan Belt, North China显示文摘This paper emphasizes that the interactive constraints of geology and isotopic dating is the best approach to construct the geological event sequence, and has compiled 106 data of reasonable isotopic ages for the igneous rocks of the Yanshan belt. We propose a sequence of mgmatic-tectonic events in the Jurassic-Cretaceous Yanshan orogen of North China. Five orogenic episodes are divided, (1) pre-and initial orogenic episode (Early Jurassic); (2) early orogenic episode (Middle Jurassic); (3) peak orogenic episode (Late Jurassic); (4) late orogenic episode (early Early Cretaceous),and (5) post-orogenic episode. Each episode is a short cycle, all of the orogenic processes construct a longer cycle, and they, in general, followed a counter-clockwise (ccw) PTt path. Finally, it is suggested that the Yanshanian movement was so intensive that the magmatism and tectonic deformation had involved all the lithosphere thickness and the lateAchaean-formed cratonic lithosphere had been significantly reworked. | DENG Jinfu, SU Shangguo, MO Xuanxue, ZHAO Guochun, XIAO Qinghiu, JI Guangyi,QIU Ruizhao, ZHAO Hailing, LUO Zhaohua, WANG Yang and LIU Cui China University of Geosciences, Beijing 100083 and Key Laboratory of Lithospheric Tectonics and Lithoprobe Techniques, Ministry of Education of China | 2004 | Acta Geologica Sinica(English Edition)2004,78,1: | 35 |
| 3 | Effects of dietary vitamin E on muscle vitamin E and fatty acid content in Aohan fine-wool sheep显示文摘value for consumers. Several laboratories have evaluated the effects of vitamin E on the fatty acid(FA) composition of muscle in sheep. However, little information is available on wool sheep, even though wool sheep breeds are an important source of mutton, especially in northern China where sheep are extensively farmed. The present study was designed to address the effects of vitamin E on muscle FA composition in male Aohan fine-wool sheep. Methods: Forty-two male Aohan fine-wool lambs(5 mo old) with similar initial body weight were randomly divided into seven groups and fed diets supplemented with 0(control group), 20, 100, 200, 1,000, 2,000, or 2,400 IU/sheep/d vitamin E for 12 mo. Three lambs from each group were slaughtered to measure vitamin E and FA content in the longissimus lumborum(LL) and gluteus medius(GM) muscles. Results: Vitamin E concentrations in the LL and GM increased significantly after 12 mo of vitamin E supplementation(P < 0.05). However, this increase did not occur in a dose-dependent manner because the muscle vitamin E concentration was highest in the 200 IU/sheep/d group. Dietary vitamin E supplementation also caused a significant reduction in SFA content and an increase in monounsaturated FA(MUFA) content in the LL and GM(P < 0.05). All six doses of vitamin E significantly increased cis9 trans11-conjugated linoleic acid(c9t11-CLA) content in the LL compared with the control group(P < 0.05). Conclusions: Dietary supplementation with vitamin E increased muscle vitamin E content and improved the nutritional value of mutton by decreasing SFA content and increasing MUFA and c9t11-CLA contents in Aohan fine-wool sheep. These effects were greatest in sheep fed a diet containing 200 IU/sheep/d vitamin E. | Kun Liu Suyun Ge Hailing Luo Dubing Yue Leyan Yan | 2013 | Journal of Animal Science and Biotechnology2013,4,4: | 6 |
| 4 | Transcriptome-wide reprogramming of N^6-methyladenosine modification by the mouse microbiome显示文摘Dear Editor, Microbiome affects many aspects of human health and disease and elicits a wide range of host responses including remarkable epigenetic changes such as DNA methylation,histone modification and non-coding RNA expression.A still poorly explored area of microbiome-host interaction is the response of host RNA modification.N^6-methyladenosine (m^6A)is the most abundant mRNA modification in mammalian cells,occurring at -3 modified adenosine residues per transcript. | Xiaoyun Wang Yan Li Wenjun Chen Hailing Shi A.Murat Eren Aleksey Morozov Chuan He Guan-Zheng Luo Tao Pan | 2019 | Cell Research2019,29,2: | 4 |
| 5 | Yanshanian Magma-Tectonic-Metallogenic Belt in East China of Circum-Pacific Domain(Ⅰ):Igneous Rocks and Orogenic Processes显示文摘Yanshanianmagma-tectonic-metalogenicbeltoftheEastChinaisapartofthecircum-Pacificdomain.Alotofpapershavebeenpublishedtodiscuss... | Deng Jinfu Mo Xuanxue Zhao Hailing Luo Zhaohua Zhao Guochun Department of Geology and Mineral Resources, China University of Geosciences, Beijing 100083 | 1999 | Journal of Earth Science1999,18,1: | 3 |
| 6 | Numerical Simulation of Transient 3-D Turbulent Heated Jet into Crossflow in a Thick-Wall T-Junction Pipe显示文摘The present work is to investigate the transient three-dimensional heated turbulent jet into crossflow in a thickwall T-junction pipe using CFD package. Two cases with the jet-to-crossflow velocity ratio of 0.05 and 0.5 are computed, with a finite-volume method utilizing κ-ε model. Comparison of the steady-state computations with measured data shows good qualitative agreement. Transient process of injection is simulated to examine the thermal shock on the T-junction component. Temporal temperature of the component is acquired by thermal coupling with the fluid. Via analysis of the flow and thermal characteristics, factors causing the thermal shock are studied. Optimal flow rates are discussed to reduce the thermal shock. | Wu Hailing, Chen Tingkuan, Luo Yushan, Wang Haijun (State Key Laboratory of Multiphase Flow in Power Engineering,Xi’an Jiaotong University, Xi’an 710049, China) | 2001 | Journal of Thermal Science2001,10,1: | 3 |
| 7 | Generation of Muscovite/ Two-Mica Granil and Intracontinental Subduction显示文摘GenerationofMuscovite/Two-MicaGranilandIntracontinentalSubduction¥DengJinfu;ZhaoHailing;LaiShaocong;LiuHouxiang;LuoZhaohua(De... | Deng Jinfu Zhao Hailing Lai Shaocong Liu Houxiang Luo Zhaohua(Department of Geology, China University of Geosciences, Beging 100083) | 1994 | Journal of Earth Science1994,13,1: | 2 |
| 8 | Controllable defects implantation in MoS2 grown by chemical vapor deposition for photoluminescence enhancement显示文摘 | Ke Wu Zhe Li Jibo Tang Xianglong Lv Hailing Wang Ruichun Luo Pan Liu Lihua Qian Shunping Zhang Songliu Yuan | 2018 | Nano Research2018,11,8: | 2 |
| 9 | Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes显示文摘Dear Editor,Obesity is caused by an imbalance between energy intake and expenditure,and has become a global epidemic with over 650 million adults affected.Adipose tissues in mammals are composed of white adipose tissue(WAT)and classical brown adipose tissue(BAT),and their balance is highly related to the occurrence of obesity.The browning of white adipocytes results in“beige”or“brite”adipocytes,which appear functionally similar to classical brown adipocytes,and can be detected in WAT deposits of animals that have been exposed to cold or other inducers(Fu et al.,2015). | Zhaomeng Cui Yang Liu Wei Wan Yuyan Xu Yehui Hu Meng Ding Xin Dou Ruina Wang Hailing Li Yongmei Meng Wei Li Wei Jiang Zengxia Li Yiming Li Minjia Tan Dengke KMa Yu Ding Jun OLiu Cheng Luo Biao Yu Qiqun Tang Yongjun Dang | 2021 | Protein & Cell2021,12,6: | 1 |
| 10 | Quality changes of whole and fresh-cut Zizania latifolia during refrigerated (1 ~C) storage显示文摘 | LUO Hail~o~ JiANG Li zHANG i i 6t al | 2012 | Food Bioorocess Technology2012,5,: | 1 |
| 11 | Effect of vascular endothelial growth factor on the early development of bovine embryos produced in vitro显示文摘 | Hailing Luo Kimura K Aoki M | 2001 | Theriogenology2001,,1: | 1 |
| 12 | Vascular Endothelial Growth Factor (VEGF) promotes the early development of bovine embryo in the presence of cumulus cells显示文摘 | Hailing Luo Kimura K MAoki | 2002 | J Vet Med Sci2002,64,11: | 1 |
| 13 | The use of ultrasound for enzymatic preparation of ACE-inhibitory peptides from wheat germ protein显示文摘 | Junqiang Jia Haile Ma Weirui Zhao Zhenbin Wang Wanmin Tian Lin Luo Ronghai He | 2009 | Food Chemistry2009,,1: | 1 |
| 14 | Effect of vascular endothelial growth factor on the early development of bovine embryos produced in vitro显示文摘 | Hailing Luo Kimura K Aoki M | 2001 | Theriogenology2001,,1: | 1 |
| 15 | Effect of vascular endothelial growth factor on the development of ovine embryos in vitro显示文摘 | Hailing Luo Shujuni Tian Shien Zhu | 2005 | Bio Reprod2005,,: | 1 |
| 16 | Vascular Endothelial Growth Factor (VEGF) promotes the early development of bovine embryo in the presence of cumulus cells显示文摘 | Hailing Luo Kimura K M Aoki | 2002 | J Vet Med Sci2002,64,11: | 1 |
| 17 | Effect of Vascular Endothelial Growth Factor on the Early Development of Bovine Embryos Produced in Vitro显示文摘 | Hailing Luo Kimura K Aoki M | | 0,,: | 1 |
| 18 | Effects of Vascular Endothelial Growth Factor on Maturation,Fertilization and developmental Competence of Bovine Oocytes显示文摘 | Hailing Luo Kimura K M Aoki | | 0,,09: | 1 |
| 19 | Vascular Endothelial Growth Factor (VEGF) Promotes the Early Development of Bovine Embryo in the Presence of Cumulus Cells显示文摘 | Hailing Luo Kimura K M Aoki | | 0,,: | 1 |
| 20 | Establishment and characterization of a dairy goat mammary epithelial cell line with human telomerase (h T ‐ MECs )显示文摘 | Huaiping Shi Hengbo Shi Jun Luo Wei Wang Abiel B. Haile Huifen Xu Jun Li | 2014 | Animal Science Journal2014,,7: | 1 |