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| 1 | Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients显示文摘AIM To investigate the clinical utility of serum annexin A2(ANXA2) as a diagnostic marker for early hepatocellular carcinoma(HCC).METHODS This study was performed in HCC Clinic of Ain Shams University Hospitals, Cairo, Egypt and included: Group 1: Fifty patients with early stage HCC(Barcelona Clinic Liver Cancer stage A); Group 2: Twenty five patients with chronic liver disease; and Control Group: Fifteen healthy, age-and sex-matched subjects who were seronegative for viral hepatitis markers. The followinglaboratory investigations were done: Viral hepatitis markers [hepatitis B surface antigen and hepatitis C virus(HCV) antibodies], HCV RNA in HCV antibody-positive patients, serum alpha fetoprotein(AFP), and serum ANXA2 levels.RESULTS In this study, 88% of HCC patients(n = 44) were HCVpositive, while HBV infection represented only 8% of all HCC patients(n = 4); and two patients were negative for both viral markers. A highly significant difference was found between patients with HCC and chronic liver disease as well as controls with regard to serum ANXA2 levels(130, IQR 15-240; 15, IQR 15-17; and 17, IQR 15-30 ng/m L, respectively). The area under the curve of ANXA2 was 0.865; the cut-off value was established to be 18 ng/mL with a diagnostic sensitivity of 74% and a specificity of 88%, while the sensitivity and specificity of AFP at the cut-off value of 200 ng/dL were 20% and 100%, respectively.CONCLUSION Serum ANXA2 may serve as a biomarker for the early detection of HCC. | Mohamed K Shaker Hanzada I Abdel Fattah Ghada S Sabbour Iman F Montasser Sara M Abdelhakam Eman El Hadidy Rehab Yousry Ahmed K El Dorry | 2017 | World Journal of Hepatology2017，9，9： | 4 |
| 2 | The knee me- niscus: structure-function, pathophysilogy, current repairtechniques, and prospects for regeneration显示文摘 | Makris E A Hadidi P Athanasious K A | 2011 | Biomateri- als2011，32，30： | 1 |
| 3 | Total synthesis of a functional designer eukaryotic chromosome 显示文摘 | Annaluru N Muller H Mitchell L A Ramalingam S Stracquadanio G Richardson S M Dymond J S Kuang Z Scheifele L Z Cooper E M Cai Y Z Zeller K Agmon N Han J S Hadjithomas M Tullman J Caravelli K Cirelli K Guo Z Y London V Yeluru A Murugan S Kandavelou K Agier N Fischer G Yang K Martin J A Bilgel M Bohutski P Boulier K M Capaldo B J Chang J Charoen K Choi W J Deng P Dicarlo J E Doong J Dunn J Feinberg J I Fernandez C Floria C E Gladowski D Hadidi P Ishizuka I Jabbari J Lau C Y L Lee P A Li S Lin D Linder M E Ling J Liu J Liu J London M Ma H Mao J Mcdade J E Mcmillan A Moore A M Oh W C Ouyang Y Patel R Paul M Paulsen L C Qiu J Rhee A Rubashkin M G Soh I Y Sotuyo N E Srinivas V Suarez A Wong A Wong R Xie W R Xu Y J Yu A T Koszul R Bader J S Boeke J D Chandrasegaran S | 2014 | Science2014，344，6179： | 1 |
| 4 | Error analysis in pipeline A/D converters and its applications 显示文摘 | Hadidi K Temes G C | 1992 | IEEE Transactions on Circuits and Systems1992，39，8： | 1 |
| 5 | Evaluation of the reaction rate constants for chlorinated ethylene and ethane decomposition in attachment-dominated atmospheric pressure dry-air plasmas显示文摘 | VITALE S A HADIDI K COHN D R | 1997 | Physics Letters A1997，232，6： | 1 |
| 6 | The knee meniscus:structure function,pathophysiology,current repair techniques,and prospects for regeneration显示文摘 | Makris E A Hadidi P Athanasiou K | 2011 | Biomaterials2011，32，30： | 1 |
| 7 | Stability of morphine and buprenorphine in whole blood 显示文摘 | Hadidi K A Oliver J S | 1998 | Int J Legal Med1998，111，3： | 1 |
| 8 | A low-power,small-size 10-bit successive-approximation ADC显示文摘 | BANIHASHEMI M HADIDI K KHOEI A | 2005 | IEICE Trans Fundamentals2005，88，4： | 1 |
| 9 | A novel open-loop high speed CMOS sample-and-hold显示文摘 | MOUSAZADEH M HADIDI K KHOEI A | 2008 | AEU International Journal of Electronics and Communica- tions2008，62，8： | 1 |
| 10 | A single amino acid substitution (Leu 160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin 显示文摘 | Hadidi H Zahlsen K Idle JR | 1997 | Food Chem Toxic1997，35，11： | 1 |
| 11 | The knee me- niscus : structurefunction, patho-physiology, current re- pair techniques,and prospects for regeneration显示文摘 | Makris E A Hadidi P Athanasiou K A | 2011 | Bio- materials2011，32，30： | 1 |
| 12 | Fuzzy level control of a tank with optimum valve movement显示文摘 | Khoei A Hadidi K Khorasani M R | 2007 | FUZZY SETS AND SYSTEMS2007，150，3： | 1 |
| 13 | A new high speed and low power four-quadrant CMOS analog multiplier in current mode 显示文摘 | NADERI A KHOEI A HADIDI K | 2009 | Int J Electron Commun2009，63，： | 1 |
| 14 | A new high speed and low power four-quadrant CMOS analog multiplier in current mode 显示文摘 | NADERI A KHOEI A HADIDI K | 2009 | Int J Elec Commun2009，63，9： | 1 |
| 15 | A new high speed and low power four-quadrant analog multiplier in current mode显示文摘 | Naderi A Khoei A Hadidi K | 2009 | International Journal of Electronics and Communications2009，63，9： | 1 |
| 16 | High gain two-stage amplifier with positive capacitive feed back compensation显示文摘 | Mersi A Pirbazari M M Hadidi K | 2015 | IEEE IET Institution of Engineering and Technology2015，9，3： | 1 |
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