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| 1 | Hepatic steatosis and fibrosis: Non-invasive assessment显示文摘Chronic liver disease is a major cause of morbidity and mortality worldwide and usually develops over many years, as a result of chronic inflammation and scarring, resulting in end-stage liver disease and its complications. The progression of disease is characterised by ongoing inflammation and consequent fibrosis, although hepatic steatosis is increasingly being recognised as an important pathological feature of disease, rather than being simply an innocent bystander. However, the current gold standard method of quantifying and staging liver disease, histological analysis by liver biopsy, has several limitations and can have associated morbidity and even mortality. Therefore, there is a clear need for safe and noninvasive assessment modalities to determine hepatic steatosis, inflammation and fibrosis. This review covers key mechanisms and the importance of fibrosis and steatosis in the progression of liver disease. We address non-invasive imaging and blood biomarker assessments that can be used as an alternative to information gained on liver biopsy. | Rustam N Karanjia Mary ME Crossey I Jane Cox Haddy KS Fye Ramou Njie Robert D Goldin Simon D Taylor-Robinson | 2016 | World Journal of Gastroenterology2016，22，45： | 6 |
| 2 | The importance of plasma apolipoprotein E concentration in addition to its common polymorphism on inter-individual variation in lipid levels:results from Apo Europe显示文摘 | Haddy N De Bacquer D Chemaly MM | 2002 | Eur J Hum Genet2002，10，12： | 1 |
| 3 | Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioio- dine therapy 显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 4 | Long-term outcome of 444 patients with distant metastases fi'om papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy 显示文摘 | Durante C Haddy N Baudin E | 2006 | ] Clin Endocrinol Metab2006，9，8： | 1 |
| 5 | Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy 显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocfinol Metab2006，91，8： | 1 |
| 6 | Long-term outcomeof 444 patients with distant metastases from papillary andfollicular thyroid carcinoma:benefits and limits ofradioiodine therapy显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 7 | Long-term outcome of 444 patients witⅡ distant metastases from papillary and follicular thyroid carcinoma:benefits and limits of radioiodine therapy显示文摘 | Durante C Haddy N Baudin E | | 0，，08： | 1 |
| 8 | Long-termoutcome of 444 patients with distant metastases from papillaryand follicular thyroid carcinoma: Benefits and limits ofradioiodine therapy 显示文摘 | DURANTE C HADDY N BAUDIN E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 9 | Repair of ionizing radiation-induced DNA damage and risk of second cancer in childhood cancer survivors显示文摘 | Haddy N Tarrier L Koscielny S | 2014 | Carcinogenesis2014，，： | 1 |
| 10 | Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma:benefits and limits of radioiodine therapy显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 11 | Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioio- dine therapy显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocr Metab2006，91，8： | 1 |
| 12 | Long-term outcome of 444 patients with distant metastases from papillary and follicular thy- roid carcinoma: benefits and limits of radioiodine therapy显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 13 | Biological variations, genetic polymorphisms and familial resemblance of TNF - alpha and IL - 6 concentrations : STANISLAS cohort 显示文摘 | Haddy N Sass C Maumus S | 2005 | Eur J Hum Genet2005，13，1： | 1 |
| 14 | Long term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma:benefits and limits of radioiodine therapy显示文摘 | Durante C Haddy N Baudin E | | 0，，08： | 1 |
| 15 | British and American Changes in Interindustry Wage Structure under Full Employment 显示文摘 | Haddy P Tolles N A | 1957 | American Economic Review1957，，39： | 1 |
| 16 | Long-term outeome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy 显示文摘 | Durante C Haddy N Baudin E | 2006 | J Clin Endocrinol Metab2006，91，8： | 1 |
| 17 | Biological variations,genetic polymorphisms and familial resemblance of TNF-alpha and IL-6 concentrations:STANISLAS cohort显示文摘 | Haddy N Sass C Maumus S | 2005 | Eur J Hum Genet2005，13，1： | 1 |
| 18 | Thyroid adenomas and carcinomas following radiotherapy for a hemangioma during infancy 显示文摘 | Haddy N Andriamboavonjy T Paoletti C | 2009 | Radiother Oncol2009，93，2： | 1 |
| 19 | Electronic nose and tongue combination for improved classification of Moroccan virgin olive oil profiles显示文摘 | Haddi Z Alami H El Bari N | 2013 | Food Research International2013，54，2： | 1 |
| 20 | Breast cancer following radiotherapy for a hemangioma during childhood 显示文摘 | Haddy N Dondon MG Paoletti C | 2010 | Cancer Causes Control2010，21，11： | 1 |
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