|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Novel immunological and nutritional-based prognostic index for gastric cancer显示文摘AIM: To assess the prognostic significance of immunological and nutritional-based indices, including the prognostic nutritional index(PNI), neutrophillymphocyte ratio(NLR), and platelet-lymphocyte ratio in gastric cancer.METHODS: We retrospectively reviewed 632 gastric cancer patients who underwent gastrectomy between1998 and 2008. Areas under the receiver operating characteristic curve were calculated to compare the predictive ability of the indices, together with estimating the sensitivity, specificity and agreement rate.Univariate and multivariate analyses were performed to identify risk factors for overall survival(OS). Propensity score analysis was performed to adjust variables to control for selection bias.RESULTS: Each index could predict OS in gastric cancer patients in univariate analysis, but only PNI had independent prognostic significance in multivariate analysis before and after adjustment with propensity scoring(hazard ratio, 1.668; 95% confidence interval:1.368-2.035). In subgroup analysis, a low PNI predicted a significantly shorter OS in patients with stage Ⅱ-Ⅲ disease(P = 0.019, P < 0.001), T3-T4 tumors(P <0.001), or lymph node metastasis(P < 0.001). Canton score, a combination of PNI, NLR, and platelet, was a better indicator for OS than PNI, with the largest area under the curve for 12-, 36-, 60-mo OS and overall OS(P = 0.022, P = 0.030, P < 0.001, and P = 0.024,respectively). The maximum sensitivity, specificity, and agreement rate of Canton score for predicting prognosis were 84.6%, 34.9%, and 70.1%, respectively.CONCLUSION: PNI is an independent prognostic factor for OS in gastric cancer. Canton score can be a novel preoperative prognostic index in gastric cancer. | Kai-Yu Sun Jian-Bo Xu Shu-Ling Chen Yu-Jie Yuan Hui Wu Jian-Jun Peng Chuang-Qi Chen Pi Guo Yuan-Tao Hao Yu-Long He | 2015 | World Journal of Gastroenterology2015，21，19： | 18 |
| 2 | A Chromosome-Scale Genome Assembly of Paper Mulberry(Bmussonetia papyrifera)Provides New Insights into Its Forage and Papermaking Usage显示文摘Paper mulberry(Broussonetia papyrifera)is a well-known woody tree historically used for Cai Lun papermaking,one of the four great inventions of ancient China.More recently,Paper mulberry has also been used as forage to address the shortage of feedstuff because of its digestible crude fiber and high protein contents.In this study,we obtained a chromosome-scale genome assembly for Paper mulberry using integrated approaches,including Illumina and PacBio sequencing platform as well as Hi-C,optical,and genetic maps.The assembled Paper mulberry genome consists of 386.83 Mb,which is close to the estimated size,and 99.25%(383.93 Mb)of the assembly was assigned to 13 pseudochromosomes.Comparative genomic analysis revealed the expansion and contraction in the flavonoid and lignin biosynthetic gene families,respectively,accounting for the enhanced flavonoid and decreased lignin biosynthesis in Paper mulberry.Moreover,the increased ratio of syringyl-lignin to guaiacyl-lignin in Paper mulberry underscores its suitability for use in medicine,forage,papermaking,and barkcloth making.We also identified the rootassociated microbiota of Paper mulberry and found that Pseudomonas and Rhizobia were enriched in its roots and may provide the source of nitrogen for its stems and leaves via symbiotic nitrogen fixation.Collectively,these results suggest that Paper mulberry might have undergone adaptive evolution and recruited nitrogen-fixing microbes to promote growth by enhancing flavonoid production and altering lignin monomer composition.Our study provides significant insights into genetic basis of the usefulness of Paper mulberry in papermaking and barkcloth making,and as forage.These insights will facilitate further domestication and selection as well as industrial utilization of Paper mulberry worldwide. | Xianjun Peng Hui Liu Peilin Chen Feng Tang Yanmin Hu Fenfen Wang Zhi Pi Meiling Zhao Naizhi Chen Hui Chen Xiaokang Zhang Xueqing Yan Min Liu Xiaojun Fu Guofeng Zhao Pu Yao Lili Wang He Dai Xuming Li Wei Xiong Wencai Xu Hongkun Zheng Haiyan Yu Shihua Shen | 2019 | Molecular Plant2019，12，5： | 18 |
| 3 | Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor显示文摘 | Jiu-liang ZHANG Hui WANG Chang CHEN Hui-fang PI Han-li RUAN Peng ZHANG Ji-zhou WU | 2009 | Acta Pharmacologica Sinica2009，30，5： | 7 |
| 4 | The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis显示文摘 | Fang Wang Wei Song Hongmei Zhao Yanni Ma Yuxia Li Di Zhai Jingnan Pi Yanmin Si Jiayue Xu Lei Dong Rui Su Mengmeng Zhang Yong Zhu Xiaoxia Ren Fei Miao Wenjie Liu Feng Li Junwu Zhang Aibin He Ge Shan Jingyi Hui Linfang Wang Jia Yu | 2017 | Cell Research2017，27，3： | 7 |
| 5 | DOES INVESTOR SENTIMENT PREDICT STOCK RETURNS? THE EVIDENCE FROM CHINESE STOCK MARKET显示文摘 | BU Hui PI Li | 2014 | Journal of Systems Science & Complexity2014，27，1： | 7 |
| 6 | Green Tea Polyphenols Attenuate High-Fat Diet-Induced Renal Oxidative Stress through SIRT3-Dependent Deacetylation显示文摘Fifty male Wistar rats were fed a standard chow diet or a high-fat(HF)diet,and different concentrations of green tea polyphenols(GTPs)(0.8,1.6,and 3.2 g/L)were administered in the drinking | YANG Hui ZUO Xue Zhi TIAN Chong HE Dong Liang YI Wei Jie CHEN Zhuo ZHANG Pi Wei DING Shi Bin YING Chen Jiang | 2015 | Biomedical and Environmental Sciences2015，28，6： | 4 |
| 7 | A new alkaloid from Lycoris aurea显示文摘新碱从 Lycoris 的灯泡被孤立脲(L’ Herit ) 植物。它的结构包括 2D NMR 通过化学、分光镜的研究作为 3-o-ethyltazettinol 被建立。 | Hui Fang Pi Peng Zhang Han Li Ruan Yong Hui Zhang Han Dong Sun Ji Zhou Wu | 2009 | Chinese Chemical Letters2009，20，11： | 4 |
| 8 | Green Tea Polyphenols Alleviate Autophagy Inhibition Induced by High Glucose in Endothelial Cells显示文摘Bovine aortic endothelial cells(BAECs)were cultured with high glucose(33 mmol/L),4 mg/L green tea polyphenols(GTPs)or 4 mg/L GTPs co-treatment with high glucose for 24 h in the presence or absence of Bafilomycin-A1(BAF).We observed that high glucose increased the accumulation of LC3-II.Treatment with BAF did not further increase the accumulation of LC3-II.Results also showed an increased level of p62 | ZHANG Pi Wei TIAN Chong XU Fang Yi CHEN Zhuo Raynard BURNSIDE YI Wei Jie XIANG Si Yun XIE Xiao WU Nan Nan YANG Hui ZHAO Na Na YE Xiao Lei YING Chen Jiang | 2016 | Biomedical and Environmental Sciences2016，29，7： | 3 |
| 9 | Self-assembling peptide nanofiber hydrogels for central nervous system regeneration显示文摘 | Xi LID Bin PI Hui WANG Xiu-Mei WANG | 2015 | Frontiers of Materials Science2015，9，1： | 2 |
| 10 | Peptide NGR Modified TiO_(2) Nanofiber Substrate for Circulating Tumor Cells Capture显示文摘The analysis of circulating tumor cells(CTCs)allows a noninvasive method of“real-time liquid biopsy”from the blood samples of cancer patients for the diagnosis of early-stage cancer,prognosis,and monitoring therapeutic response.In this study,we develop a simple,inexpensive,and reliable method that utilizes a small molecule peptide,the asparagine-glycine-arginine(NGR),as a capture probe for the selective enrichment and isolation of circulating tumor cells(CTCs).The multiscale TiO_(2) nanofibers are obtained by electrospinning and calcination.Bovine serum albumin(BSA)is decorated onto TiO_(2) nanofiber surfaces to inhibit non-target cell adhesion,while NGR peptides are conjugated onto the TiO_(2)-BSA surface through the glutaraldehyde(GA)to specifically capture the target cells.The TiO_(2)-BSA-NGR substrate exhibits a high capture sensitivity and efficiency from the mimical blood samples with PC-3 cancer cells as low as 10 cells/mL.The TiO_(2) nanofiber substrate can be a promising strategy for the capture and enumeration of CTCs in cancer progression monitoring. | Changchong Chen Zeen Wu Pi Ding Na Sun Hui Liu Yong Chen Zhili Wang Renjun Pei | 2020 | Advanced Fiber Materials2020，2，4： | 2 |
| 11 | A new cycloartane triterpenoid from the leaves and stems of Fritillaria hupehensis显示文摘A new triterpenoid has been isolated from the leaves and stems of Fritillaria hupehensis Hsiao et K.C.Hsia.Its structure wasestablished as(23Z)-9,19-cycloart-23-ene-3α,25-diol 1 through chemical and spectroscopic studies including 2D NMR.Anotherknown triterpenoid 9,19-cycloart-25-ene-3β,24ξ-diol 2 was also isolated. | Hui Fang Pi Peng Zhang Tian Zhu Han Li Ruan Yong Hui Zhang Han Dong Sun Ji Zhou Wu | 2007 | Chinese Chemical Letters2007，18，4： | 2 |
| 12 | Age-related changes in bone biochemical markers and their relationship with bone mineral density in normal Chinese women显示文摘 | Yin-Zhen Pi Xian-Ping Wu Shi-Ping Liu Xiang-Hang Luo Xing-Zhi Cao Hui Xie Er-Yuan Liao | 2006 | Journal of Bone and Mineral Metabolism2006，，5： | 1 |
| 13 | Online SVMRegression Algorithm-based Adaptive Inverse Control显示文摘 | WANG Hui PI Daoying SUN Youxian | 2007 | Neurocomputing2007，70，46： | 1 |
| 14 | Online SVM regression algorithm-based adaptive inverse control显示文摘 | WANG Hui PI Dao-ying SUN You-xian | 2007 | Neuro- Computing2007，70，46： | 1 |
| 15 | The frequency and clinicalsiginfieance of thrombocy topenia complicating critical illness: asystematic revies显示文摘 | HUI PI COOK DJ LIM W | 2011 | Chest2011，139，2： | 1 |
| 16 | Early enteral nutrition supplemented with probiotics improved the clinical outcomesin patients with severe head injury: protocol for a meta-analysis of randomizedcontrolled trials显示文摘目的:探讨添加益生菌的早期肠内营养对重型颅脑损伤患者临床结局的影响.方法:电子检索PubMed、Cochrane CentralRegister of Controlled Trials(CENTRAL)、中国知网(China National Knowledge Infrastructure,CNKI)、万方及中国生物医学文献数据库(Chinese Biomedical Literature Database,CBM)中有关添加益生菌的早期肠内营养对重型颅脑损伤患者临床结局影响的随机对照研究(Randomizedcontrolledtrials,RCTs),并手工检索合格研究及主题相关综述的参考文献.2位研究者独立筛查文献、提取资料、评价合格研究的偏倚风险后,采用STATA12.0软件行Meta分析.伦理与发布:本研究所有分析均基于已发表研究中所报告数据,因此不需要签署伦理许可和患者知情同意书.本系统评价全文完成后,将发表于同行评审的期刊杂志. | Li-Juan Yi Xu Tian Wei-Qing Chen Li Ma Huan He Hui Chen Cheng-XiangWu Yuan-Ping Pi | 2017 | TMR Integrative Nursing2017，1，2： | 1 |
| 17 | Online SVM Regression Algorithm-based Adaptive Inverse Control 显示文摘 | Hui Wang Daoying Pi Youxian Sun | 2007 | Neurocomputing2007，，70： | 1 |
| 18 | Online SVM regression algorithm -based adaptive inverse control 显示文摘 | Wang Hui Pi Daoying Sun Youxian | 2007 | Nerocomputing2007，70，： | 1 |
| 19 | Online SVM regression algorithm-based adaptive inverse control显示文摘 | WANG HUI PI DAO-YING SUN YOU-MAN | 2007 | Neurocomputing2007，70，46： | 1 |
| 20 | Tracheomalacia and bronchomalacia in children: incidence and patient characteristics显示文摘 | Boogaard R Hui jsmans S H Pi jnenburg M W | 2005 | Chest2005，28，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员