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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Short-term and long-term effects of vocal distortion on song maintenance in zebra finches显示文摘 | HOUGH G VOLMAN S | 2002 | Neurosci2002，22，： | 1 |
| 3 | Internal connectivity of the homing pigeon (Columba livia) hippocampal formation:an anterograde and retrograde tracer study显示文摘 | Kahn M C Hough Ⅱ G E Eyck G R T | 2003 | J Comp Neurol2003，459，2： | 1 |
| 4 | Autoimmune pancreatitis: differentiation from pancreatic carcinoma and normal pancreas on the basis of enhancement characteristics at dual-phase CT 显示文摘 | Takahashi N Fletcher J G Hough D M | 2009 | AJR Am J Roentgenol2009，193，2： | 1 |
| 5 | Survival analysis applied to sensory shelf life of foods显示文摘 | HOUGH G LANGOHR K GOMEZ G | 2003 | Journal of Food Science2003，68，1： | 1 |
| 6 | Decreased prefrontal CaMK ]] alpha mRNA in bipolar illness显示文摘 | Xing G Russell S Hough C | 2002 | Neuroreport2002，13，4： | 1 |
| 7 | Autoim- mune panereatitis: differentiation from pancreatic carcino- ma and normal pancreas on the basis of enhancement characteristics at dual-phase CT 显示文摘 | Takahashi N Fletcher J G Hough D M | 2009 | Am J Roentgenol2009，193，2： | 1 |
| 8 | Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants显示文摘 | Hough M A Grossmann J G Antonyuk S V | 2004 | Proc Natl Acad Sci USA2004，101，16： | 1 |
| 9 | Reduction of early B lymphocyte precursors in transgenic mice overexpressing the murine heat-stable antigen显示文摘 | CHAPPEL M S SAUVAGEAU G | 2005 | Cell Immunol2005，236，12： | 1 |
| 10 | Evidence for abnormalities of cortical development in adolescent-onset schizophrenia显示文摘 | Voets NL Hough MG Douaud G | | 0，，： | 1 |
| 11 | A model for the shape of the fourier amplitude spectrum of acceleration at high frequencies显示文摘 | Anderson J G Hough S | 1984 | Bulletin of the Seismological Society of America1984，74，5： | 1 |
| 12 | Survival analysis applied to sensory shelf life of foods显示文摘 | HOUGH G LANGOHR K CEMEZ G | 2003 | J Food Sci2003，68，1： | 1 |
| 13 | Sensory shelf-life predictions by survival analy sis accelerated storage models显示文摘 | Hough G | 2006 | Food Quality and Pref erence2006，17，4： | 1 |
| 14 | Fugacity modelling to predict the distribution of organic contaminants in the soil: Oil matrix of constructed biopiles 显示文摘 | POLLARD S J T HOUGH R L KIM K H BELLARBY J PATON G SEMPLE K T COULON F | 2008 | Chemosphere2008，71，： | 1 |
| 15 | Survival analysis applied to sensory shelf life of foods显示文摘 | Hough G Langohr K Gomez G | 2003 | Journal of Food Science2003，68，1： | 1 |
| 16 | Decamethylcucurbit uril显示文摘 | Flinn A Hough G C Stoddart J F | 1992 | Angew Chem Int Ed Engl1992，31，： | 1 |
| 17 | Decamethyleueur- bit uril 显示文摘 | Flinn A Hough G C Stoddart J F | 1992 | Angew Chem Ira Ed1992，31，11： | 1 |
| 18 | Thermal resistance of β-galactosidase in dehydrated dairy model systems as affected by physical and chemical changes显示文摘 | Buera MP Hough G | 2002 | Food Chemistry2002，76，： | 1 |
| 19 | Modification of the polyeth-ylene glycol 6000 precipitation method for recoveing human and indicator viruses from oysters and mussels显示文摘 | Lewis G D Hough A Green D H | 1996 | New Zealand Journal of Marine and Freshwater Research1996，30，： | 1 |
| 20 | Can good architecture meet the market test? 显示文摘 | HOUGH D E KRATZ C G | 1983 | Journal of Urban Economics1983，14，1： | 1 |
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