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| 1 | Cervical inlet patch-optical coherence tomography imaging and clinical significance显示文摘AIM:To demonstrate the feasibility of optical coherence tomography(OCT)imaging in differentiating cervical inlet patch(CIP)from normal esophagus,Barrett'sesophagus(BE),normal stomach and duodenum. METHODS:This study was conducted at the Veterans Affairs Boston Healthcare System(VABHS).Patients undergoing standard esophagogastroduodenoscopy at VABHS,including one patient with CIP,one representative patient with BE and three representative normal subjects were included.White light video endoscopy was performed and endoscopic 3D-OCT images were obtained in each patient using a prototype OCT system.The OCT imaging probe passes through the working channel of the endoscope to enable simultaneous video endoscopy and 3D-OCT examination of the human gastrointestinal(GI)tract.Standard hematoxylin and eosin(H and E)histology was performed on biopsy or endoscopic mucosal resection specimens in order to compare and validate the 3D-OCT data. RESULTS:CIP was observed from a 68-year old male with gastroesophageal reflux disease.The CIP region appeared as a pink circular lesion in the upper esophagus under white light endoscopy.OCT imaging over the CIP region showed columnar epithelium structure,which clearly contrasted the squamous epithelium structure from adjacent normal esophagus.3D-OCT images obtained from other representative patients demonstrated distinctive patterns of the normal esophagus,BE,normal stomach,and normal duodenum bulb.Microstructures,such as squamous epithelium,lamina propria, muscularis mucosa,muscularis propria,esophageal glands,Barrett's glands,gastric mucosa,gastric glands, and intestinal mucosal villi were clearly observed with OCT and matched with H and E histology.These results demonstrated the feasibility of using OCT to evaluate GI tissue morphology in situ and in real-time. CONCLUSION:We demonstrate in situ evaluation of CIP microstructures using 3D-OCT,which may be a useful tool for future diagnosis and follow-up of patients with CIP. | Chao Zhou Tejas Kirtane Tsung-Han Tsai Hsiang-Chieh Lee Desmond C Adler Joseph M Schmitt Qin Huang James G Fujimoto Hiroshi Mashimo | 2012 | World Journal of Gastroenterology2012，18，20： | 3 |
| 2 | R E Nanotube Nanodevice显示文摘 | PHILIP G COLLINS A ZETTL HIROSHI BANDO ANDREAS THESS SMALLEY | 1997 | Science1997，278，： | 1 |
| 3 | Effect of some plant growth regulator treatments on apple fruit ripening显示文摘 | ANDREA M MAURIZO V HIROSHI G | 1998 | Plant Growth Regulation1998，25，2： | 1 |
| 4 | Experimental study on the wind-induced vibration of a dry inclined cable-Part I: Phenomena 显示文摘 | Cheng Shaohong Guy L Larose Mike G Savage Hiroshi Tanaka Peter A Irwin | 2008 | Journal of Wind Engineering and Industrial Aerodynamics2008，96，12： | 1 |
| 5 | Harmonic sound stream seg-regation using localization and its application to speechstream segregation 显示文摘 | TOMOHIRO N HIROSHI G 0 | 1999 | Speech Communication1999，27，10： | 1 |
| 6 | Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195显示文摘 | Hiroshi N Keresztes G Yoshifumi S | 2006 | J Bacteriol2006，188，6： | 1 |
| 7 | SIRS- associated coagulopa-thy and organ dysfunction in critically ill patient with thrombocytopenia显示文摘 | Hiroshi O Satoshi G Toshiaki 1 | 2007 | Shock2007，28，4： | 1 |
| 8 | Stimulation of ‘Fuji'apple skin color by ethephon and phosphorus-calcium mixed compounds in relation to flavonoid synthesis显示文摘 | ZhengHua Li Hiroshi G Shuichi I | 2002 | Scientia Horticulturae2002，94，1： | 1 |
| 9 | Enumeration of bacterial cell Numbers and Detection of Significant Bacteriuria by Use of a New Flow Cytometry-Based Device显示文摘 | Hiroshi O Toshiri S Akinobu G | 2006 | Clin Micro2006，44，10： | 1 |
| 10 | Evaportion rate of cop- per from molten iron by urea spraying under reduced pressure 显示文摘 | Toru Maruyama Hiroshi G Katayama | 1998 | 鉄と钢1998，84，4： | 1 |
| 11 | Stimulation of cAMP production and cyclooxygenase-2 by prostaglandin E 2 and selective prostaglandin receptor agonists in murine osteoblastic cells显示文摘 | Yoko Sakuma Ziaodong Li Carol C Pilbeam Cynthia B Alander Daichi Chikazu Hiroshi Kawaguchi Lawrence G Raisz | 2003 | Bone2003，，5： | 1 |
| 12 | Transmission system using self- oscillating multi- phase liquid membrane system 显示文摘 | Hiroshi Y Kazuo M Yohichi G | 1997 | Chemistry Letters1997，10，： | 1 |
| 13 | Effect of Diameter on the Burning of Crude Oil Pool Fires 显示文摘 | Hiroshi Koseki MULHOLLAND G W | 1991 | Fire Teehnology1991，27，1： | 1 |
| 14 | Control of tillering in rice显示文摘 | Li X Qian Q Fu Z Wang Y Xiong G Zeng D Wang X Liu X Teng S Hiroshi F Yuan M Luo D Han B Li J | 2003 | Nature2003，422，6932： | 1 |
| 15 | Methane reforming with CO2 in molten salt using FeO catalyst显示文摘 | Nobuyuki G Yoshinori O Hiroshi K | 2002 | Solar Energy2002，72，3： | 1 |
| 16 | Development of a numerical simulation system toward comprehensive assessments of urban wanning countermeasures including their impacts upon the urban buildings'energy-demands显示文摘 | Yukihiro K Yutaka G Hiroshi Y | 2003 | Applled Energy2003，76，： | 1 |
| 17 | How does the mitochondrial ADP/ATP carrier distinguish transportable ATP and ADP from untransportable AMP and GTP? Dynamic modeling of the recognition/ translocation process in the major substrate binding region显示文摘 | Satoru G Hiroshi C Eiji M | 2002 | Biochim Biophys Acta2002，1589，23： | 1 |
| 18 | Evaluation of insulin secretion of isolated rat islets cultured in extra cellular matrix显示文摘 | Natsuki N Yuanjun G Hiroshi H | 2001 | Cell Transplantation2001，32，10： | 1 |
| 19 | Ultrasonic micromixer for microfluidic systems显示文摘 | Zhen Y Sohei M Hiroshi G | 2001 | Sensors and Actuators A2001，93，： | 1 |
| 20 | Mullite whiskers from precursor gel powders 显示文摘 | Mohamed G M U Hiroshi A Zenjiro N | 1990 | J Am Ceram Soc1990，73，9： | 1 |
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