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| 1 | Propensity score analysis demonstrated the prognostic advantage of anatomical liver resection in hepatocellular carcinoma显示文摘AIM:To compare the prognoses of hepatocellular carcinoma(HCC)patients that underwent anatomic liver resection(AR)or non-anatomic liver resection(NAR)using propensity score-matched populations.METHODS:Between January 2002 and December2010,268 consecutive HCC patients,including 110 and158 patients that underwent AR and NAR,respectively,were retrospectively enrolled in this study.Forty-four patients from each group were selected and matched using logistic multivariate analysis followed by propensity score analysis.RESULTS:In the whole analysis set,the histological background of the liver,liver function,and tumor marker levels differed significantly among the groups.Although the overall survival(OS)and recurrence-free survival rates of the two groups did not differ significantly in the whole analysis set,the OS of the AR group was significantly longer than that of the NAR group after propensity matching(76.2±6.3 mo vs 58.9±6.3mo;P=0.0039).Although AR(HR=0.456,P=0.039)was found to be a prognostic factor in the univariate analysis,only vascular invasion(HR=0.228,P=0.002)and the hepatocyte growth factor level(HR=52.366,P=0.035)were subsequently found to be independent prognostic factors.CONCLUSION:AR conveys a survival advantage over NAR in specific subpopulations of HCC patients with tumors of less than 5 cm in diameter,single tumor,and good liver function. | Masayuki Ishii Toru Mizuguchi Masaki Kawamoto Makoto Meguro Shigenori Ota Toshihiko Nishidate Kenji Okita Yasutohsi Kimura Thomas T Hui Koichi Hirata | 2014 | World Journal of Gastroenterology2014，20，12： | 12 |
| 2 | 钻孔千斤顶压裂测量技术的发展和原地测量显示文摘为了测量距地表1 000m以下位置的地壳应力状态,我们研究并开发了钻孔千斤顶压裂技术。技术的原理是:当钻孔千斤顶对钻孔壁加载时,与钻孔轴向平行的方向将会产生两个相对的新裂隙;卸载之后,如果千斤顶对钻孔壁的同一个地方进行施压,这对裂隙将会再次张开。与钻孔轴向垂直的平面上的两个主应力的大小和方向分别是由重张压力和裂隙的方向决定的。这个技术与水压致裂法相似。因此,测量深度没有理论上的限制。这个技术的特点就是它可以产生一对任意方向的轴向裂隙,可以测量裂隙张开的位移大小,根据测量结果可以精确计算重张压力的大小。在实地测试中,先用水压致裂法形成裂隙,再用钻孔压力千斤顶法加以与水压近似相等的压力值使之重张。本文介绍了我们的数值分析结果、实验室实验和现场测试。 | Yokoyama T Ogawa K Sano O Hirata A Mizuta Y 徐伟(译) 张雷 姚瑞 沙鹏(校) | 2011 | 国际地震动态2011，，1： | 3 |
| 3 | 步行6min负荷超声心动图预测结缔组织病患者远期显性肺高血压显示文摘肺高血压是结缔组织病(connective tissue disease,CTD)的主要死因。运动负荷试验已用于筛查早期肺高血压[1],但由于缺乏相关证据,最新的指南已停止其作为发现肺高血压的方法。近期研究发现平均肺动脉压(mean pulmonary arterial pressure,mPAP)升高导致心输出量异常可用于评估肺高血压进展及肺功能分级[2]。该研究将步行6min后的超声心动图参数作为非侵入性负荷试验。 | Kusunose K Yamada H Hotchi J Bando M Nishio S Hirata Y Ise T Yamaguchi K Yagi S Soeki T Wakatsuki T Kishi J Sata M 曲浥晨 | 2015 | 中华高血压杂志2015，23，10： | 3 |
| 4 | Ice formation and heat transfer with water flow around isothermally cooled cylinders arranged in a line显示文摘 | HIRATA T MATSUI H | 1990 | Jounal of Heat Transfer1990，112，3： | 2 |
| 5 | Increased prevalence of intestinal inflammation in patients with liver cirrhosis显示文摘AIM To investigate the pathophysiology of the digestive tract in patients with liver cirrhosis.METHODS In 42 cirrhotic patients and 20control subjects, the following fecal proteinswere measured by enzyme-linkedimmunosorb6nt assay: albumin (Alb ),transferrin (Tf), and al-antitrypsin (a,-AT) as amarker for intestinal protein l0ss, hemoglobin(Hb) for bleeding, PMN-eIastase for intestinalinflammation, and secretory lgA for intestinalimmunity.RESULTS The fecaI concentrations of Hb, Alb,Tf, al-AT, and PMN’eIastase were increased in13 (3l%), 8(19%), l0(24%), 6(14%), and 1l(26%) cases among 42 patients, resPectiveIy.F6cal concentration of secretory IgA wasdecreased in 7 (l7%) of 42 patients. However,these fecal concentrations were not related tothe severity or etiology of liver cirrhosis. Theserum Alb level was significantIy decreased inpatients with intestinal protein Ioss c0mpared tothat in patients without intestinal protein loss.CONCLUSION These findings suggest that: rob6sides the weIl’known pathological conditions,Such as bleeding and protein loss, intestinaIinflammati0n and decreased intestinaI immunityare found in cirrhotic patients, @ intestinalprotein loss contributes to hypoalbuminemia incirrhotic patients, and @ intestinaI inflammationshouId not b6 0verlooked in cirrhotic patients,since it may contribute to or cause intestinalprotein Ioss and oth6r various pathologicalconditions. | Saitoh O Sugi K Lojima K Matsumoto H Nakagawa K Kayazawa M Tanaka S Teranishi T Hirata I Katsu Ki K | 1999 | World Journal of Gastroenterology1999，5，5： | 2 |
| 6 | Asymmetric hydrolysis of enol esters with two esterases from Marchantia polymorpha 显示文摘 | Hirata T Shimoda K Kawano T | 2000 | Tetrahedron : Asymmetry2000，11，5： | 1 |
| 7 | Paroxysmal Kinesigeuic choreoathetosis with abnormal electroencephalogram during attacks 显示文摘 | Hirata K Katayama S saito T | 1991 | Epilepsia1991，32，： | 1 |
| 8 | Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages显示文摘 | Yasuda T Hirata K Ishida T | 2007 | J Atheroscler Thromb2007，14，4： | 1 |
| 9 | P-Selectin glycoprotein ligand 1 ( PSGL-1)is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration显示文摘 | Hirata T Merrill S G Aab M | 2000 | The Journal of Experimental Medicine2000，192，11： | 1 |
| 10 | ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase 显示文摘 | Hirata A Ogawa S Kometani T | 2002 | Cancer Res2002，62，9： | 1 |
| 11 | Immunohistochemical localization of endothelial cell derived lipase in atherosclerotic human coronary arteries 显示文摘 | Azumi H Hirata K lshida T | 2003 | Cardiovasc Res2003，58，3： | 1 |
| 12 | Hemocyanin a most likely inducer of black spots in kuruma prawn Penaeus japonicus during storage显示文摘 | Adachi K Hirata T Nagai K | 2001 | Journal of Food Science2001，66，8： | 1 |
| 13 | Activation of diacylglycerol O-acyl-transferase 1 gene results in increased tumor necrosis factor-alphagene expression in 3T3-L1 adipocytes 显示文摘 | Hirata T Unoki H Bujo H | 2006 | FEBS Lett2006，580，21： | 1 |
| 14 | Free-living cells releasedfrom thalli of Sargassum horneri (Phaeophyta) in culture 显示文摘 | Uchida T Arima S Hirata S | 1996 | Bot Mar1996，39，123456： | 1 |
| 15 | Effective 30-hour preservation of canine lungs with modified ET-Kyoto solution显示文摘 | Wada H Liu C J Hirata T | 1996 | Ann Thorac Surg1996，61，： | 1 |
| 16 | Recruitment of CCR6-expressing Th17 cells by CCL20 secreted from IL-1β,TNF-α,and IL-17A stimulated endometriotic stromal cells显示文摘 | Hirata T Osuga Y Takamura M | 2010 | Endocrinology2010，151，11： | 1 |
| 17 | Electronic conductivity measurement of Sm-and La-doped ceri;ceramics by Hebb-Wagner meathod显示文摘 | SHIMONOSONO T HIRATA Y EHIRA Y | 2004 | Solid State Ionics2004，174，14： | 1 |
| 18 | Secretary mechanism of immunoreactive endothelin incultured borine endothelial cell显示文摘 | Emori T Hirata Y Ohta K | 1989 | Biophsiol Res Commun1989，160，1： | 1 |
| 19 | Control of railway vehicle active suspension显示文摘 | HIRATA T | 1995 | Automatica1995，31，1： | 1 |
| 20 | Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topeisomerase IV: contribution to reducing in vitro e- mergence of qainolone-resistant Streptococcus pneumoniae 显示文摘 | Okumura R Hirata T Onodera Y | 2008 | J Antimi- crob Chemother2008，62，1： | 1 |
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