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| 1 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 2 | Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic review显示文摘 | Herbison P Hay-Smith J Ellis G | 2003 | BMJ2003，326，7394： | 1 |
| 3 | Effectiveness of anticho- linergic drugs compared with placebo in the treatment of overactive bladder: systematic review 显示文摘 | Herbison P Hay-Smith J Ellis G | 2003 | BMJ2003，326，7394： | 1 |
| 4 | Obstetric prac- tice and the prevalence of urinary incontinence three months after delivery 显示文摘 | Wihun P D Herbison R M Herbimn G P | 1996 | Br J Obstet Gyunecol1996，103，2： | 1 |
| 5 | Functional applianee treatment assessed using the PAR index 显示文摘 | Wijayaratne D Harkness M Herbison P | 2000 | Aust Orthod J2000，16，3： | 1 |
| 6 | Incidence of thrombotic cardiovascular events in patients taking celecoxib compared with those taking rofecoxib:interim results from the New Zealand Intensive Medicines Monitoring Pregrammed显示文摘 | Harrison-Woolrych M Herbison P McLean R | 2005 | Drug Safety2005，28，5： | 1 |
| 7 | Stress urinary incontinence following childbirth:Primigr avida's obstetric and other dangerous factors显示文摘 | Glazener C M A Herbison G P | 2006 | BJOG2006，113，： | 1 |
| 8 | Interventions for relieving the pain and discomfort of screening mammography显示文摘 | Miller D Livingstone V Herbison P | 2008 | Cochrane Database Syst Rev2008，，00： | 1 |
| 9 | The im- pact of body mass index on semen parameters and repro- ductive hormones in human males: a systematic review with meta-analysis 显示文摘 | MacDonald A A Herbison G P Showell M | 2010 | Hum Reprod Update2010，16，3： | 1 |
| 10 | A randomized controlled trial toinvestigate the effects of water-based exercise to improve fallsrisk and physical function in older adults with lower-extremityosteoarthritis显示文摘 | Hale LA Waters D Herbison P | | 0，，01： | 1 |
| 11 | Sexual function,de-livery mode history,pelvic floor muscle exercises and in-continence:a cross-sectional study six years post-partum显示文摘 | Dean N Wilson D Herbison P | 2008 | Aust N Z J Obstet Gynaecol2008，48，3： | 1 |
| 12 | Global Registry of Acute Cor- onary Events (GRACE) hospital discharge risk score accurately predicts long- term mortality post acute coronary syndrome 显示文摘 | Tang EW Wong CK Herbison P | 2007 | Am Heart J2007，153，1： | 1 |
| 13 | Traditional Chinese acupuncture as an antiemetic显示文摘 | Weightman W M Zacharias M Herbison P | 1987 | Br Med J (Clin Res Ed)1987，295，6610： | 1 |
| 14 | Global Registry of Acute Coro- nary Events (GRACE) hospital discharge risk score accuratelypredicts long - term mortality post acute coronary syndrome 显示文摘 | Tang EW Wong CK Herbison P | 2007 | Am Heart J2007，153，1： | 1 |
| 15 | func- tional appliance treatment assessed using the PAR index 显示文摘 | Wijayaratne D Harkness M Herbison P | 2008 | Australian Orthodontic Joum- al2008，16，： | 1 |
| 16 | Mandibular changes during functional appliance treatment 显示文摘 | Nelson C Harkncss M Herbison P | 1993 | Am J Orthod Dentofac Or- thop1993，104，2： | 1 |
| 17 | Faecal incontinence persisting after childbirth:a 12 year longitudinal study显示文摘 | Maearthur C Wilson D Herbison P | 2013 | BJOG2013，120，2： | 1 |
| 18 | Bladder neck mobility and urethral closure pressure as predictors of genuine stress incontinence显示文摘 | Dietz HP Clarke B Herbison P | 2002 | Int Urogynecol J Pelvic Floor Dysfunct2002，13，5： | 1 |
| 19 | Global Registry of Acute Cor- onary Events (GRACE) hospital discharge risk score accurately predicts long- term mortality post acute coronary syndrome 显示文摘 | Tang EW Wong CK Herbison P | 2007 | Am Heart J2007，153，1： | 1 |
| 20 | New postnatal urinary incontinence:obstetrics and other risk factors in primiparae显示文摘 | GLAZENER C M HERBISON G P MACARTHUR C | 2006 | Br J Obstet Gynaecol2006，113，2： | 1 |
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