|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | Low-temperature exfoliated graphenes: vacuum-promoted exfoliation and electrochemical energy storage显示文摘 | Lv W Tang D M He Y B | 2009 | ACS Nano2009，3，11： | 1 |
| 3 | Energetics of charged point defects in rutile TiO2 by density functional theory显示文摘 | LI X FINNIS M W HE J BEHERA R K PHILLPOT S R SINNOTT S B DICKEY E C | 2009 | Acta Materialia2009，57，： | 1 |
| 4 | Hepatitis B virus with a pro- posed genotype I was found in sichuan province,China显示文摘 | TONG W B HE J L SUN L | 2012 | J Med Viro12012，84，6： | 1 |
| 5 | Cloning and characterization of testis-specific spermatogenesis associated gene homologous to human SPATA4 in rat 显示文摘 | LIU S F HE S LIU B W | 2004 | Biol Pharm Bull2004，27，： | 1 |
| 6 | Distribution, degradation and dynamics of dissolved organic carbon and its major compound classes in the Pearl River estuary, China显示文摘 | HE B Y DAI M H ZHAI W D | 2010 | Marine Chemistry2010，119，14： | 1 |
| 7 | An innovative design for using flexible printed coils for magnetostrictive-based longitudinal guided wave sensors in steel strand inspection显示文摘 | Tse P W Liu X C Liu Z H Wu B He C F Wang XJ | 2011 | Smart Materials and Structures2011，20，05： | 1 |
| 8 | Experimental study on the performance of CO2 residential air-conditioning system with anInternal heat exchanger显示文摘 | Tao Y B He Y L Tao W Q Wu Z G | | 0，，01： | 1 |
| 9 | Decomposition of Abies faxoniana litter varies with freeze–thaw stages and altitudes in subalpine/alpine forests of southwest China 显示文摘 | Zhu J He X Wu F Yang W Tan B | 2012 | Scand J For Res2012，27，： | 1 |
| 10 | Emergence, circulation, and spatiotemporal phylogenetie analysis of eoxsaekievirus a6 - and coxsackievirus al0 - associated hand, foot, and mouth disease infections from 2008 to 2012 in shenzhen, china显示文摘 | He Y Q Chen L Xu W B | 2013 | J Clin Microbiol2013，51，11： | 1 |
| 11 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 12 | Spectroelectrochemistry of solid in-dirubin and its sulfdnated form显示文摘 | Hu X W He J B You Y H | 2011 | Electrochim Acta2011，56，3： | 1 |
| 13 | Modification of polysulfide sealant with polysulfide poly-thio-urethane-urea显示文摘 | Quan Y W He P Zhou B J | 2007 | Journal of Applied Polymer Science2007，106，4： | 1 |
| 14 | A continuum model for size-dependent deformation of elastic films of nanoscale thickness显示文摘 | He L H Lim C W Wu B S | 2004 | International Journal of Solids and Structures2004，41，： | 1 |
| 15 | Novel KOH electrolyte for one-step electrochemical synthesis of high purity solid K2FeO4:Comparison with NaOH 显示文摘 | He W C Wang J M Shao H B | 2005 | Electrochemistry Communications2005，7，6： | 1 |
| 16 | Health benefit evaluation offthe energy use scenarios in Beijing,China 显示文摘 | Pan X C Yue W He K B | 2007 | Science of theTotal Environment2007，374，23： | 1 |
| 17 | Cloning and characterization of zebrafish SPATA4 gene and analysis of its gonad specific ex- pression 显示文摘 | LIU S F LIU B W HE S | 2005 | Biochemistry (Mosc)2005，70，： | 1 |
| 18 | Exercise Intervention May Prevent Depression显示文摘 | HE S B TANG W G TANG W J | 2012 | Int J Sports Med2012，33，7： | 1 |
| 19 | Two-stage nonnegative sparse representation for large-scale face recognition显示文摘 | HE R ZHENG W S HU B G | 2013 | Neural Networks and Learning Systems IEEE Transactions on2013，24，1： | 1 |
| 20 | Antimicrobial,cytotoxic lignans and terpenoids from the twigs ofPseudolarix kaempferi 显示文摘 | He W J Chu H B Zhang Y M | 2011 | Planta Med2011，77，17： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员