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| 1 | Recent advances of wearable and flexible piezoresistivity pressure sensor devices and its future prospects显示文摘The human skin inspired soft electronic devices have attracted broadly research attention in the past decades as the promising potential applications in health monitoring and diagnosis,robotics,and prosthetics.The soft wearable piezoresistivity pressure sensor is one of the most attractive candidates for the development of advanced electronic skin for its simple mechanism,compact structure,low cost and power energy consumption and ease of signal acquisition and transforms advantages.In this review,we will explore the recent progress and achievements in the field of piezoresistivity pressure sensor,focusing on the fundamentals of the piezoresistivity pressure sensor and the materials related to the devices,including active materials,substrate materials,and electrode materials.Subsequently,the challenges and outlook are discussed.We list several current challenges perspectives on the development of pressure sensors.Several critical topics for the optimization of the sensitivity and working range of sensing devices toward practical applications are discussed.Finally,perspectives on the slip and force vectors sensors,the developing technologies for multi-function and high-resolution sensor systems and signals process technologies are examined to highlight the near future development tendency in piezoresistivity pressure sensor research field. | Jiang He Yufei Zhang Runhui Zhou Lirong Meng Tao Chen Wenjie Mai Caofeng Pan | 2020 | Journal of Materiomics2020，6，1： | 9 |
| 2 | Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells显示文摘Shenkang injection (SKI) is a classic prescription composed of Radix Astragali, rhubarb, Astragalus, Safflower, and Salvia. This treatment was approved by the State Food and Drug Administration of China in 1999 for treatment of chronic kidney diseases based on good efficacy and safety. This study aimed to investigate the protective effect of SKI against high glucose (HG)-induced renal tubular cell senescence and its underlying mechanism. Primary renal proximal tubule epithelial cells were cultured in (1) control medium (control group), medium containing 5 mmol/L glucose;(2) mannitol medium (mannitol group), medium containing 5 mmol/L glucose, and 25 mmol/L mannitol;(3) HG medium (HG group) containing 30 mmol/L glucose;(4) SKI treatment at high (200 mg/L), medium (100 mg/L), or low (50 mg/L) concentration in HG medium (HG+ SKI group);or (5) 200 mg/L SKI treatment in control medium (control+ SKI group) for 72 h. HG-induced senescent cells showed the emergence of senescence associated heterochromatin foci, up-regulation of P16INK4 and cyclin D1, increased senescence-associated β-galactosidase activity, and elevated expression of membrane decoy receptor 2. SKI treatment potently prevented these changes in a dose-independent manner. SKI treatment prevented HG-induced up-regulation of pro-senescence molecule mammalian target of rapamycin and p66Shc and down-regulation of anti-senescence molecules klotho, sirt1, and peroxisome proliferator-activated receptor-g in renal tubular epithelial cells. SKI may be a novel strategy for protecting against HG-induced renal tubular cell senescence in treatment of diabetic nephropathy. | Biqiong Fu Jie Yang Jia Chen Lirong Lin Kehong Chen Weiwei Zhang Jianguo Zhang Yani He | 2019 | Frontiers of Medicine2019，13，2： | 8 |
| 3 | Intensive phototherapy vs.exchange transfusion for the treatment of neonatal hyperbilirubinemia:a multicenter retrospective cohort study显示文摘Background:Intensive phototherapy(IPT)and exchange transfusion(ET)are the main treatments for extreme hyperbilirubinemia.However,there is no reliable evidence on determining the thresholds for these treatments.This multicenter study compared the effectiveness and complications of IPT and ET in the treatment of extreme hyperbilirubinemia.Methods:This retrospective cohort study was conducted in seven centers from January 2015 to January 2018.Patients with extreme hyperbilirubinemia that met the criteria of ET were included.Patients were divided into three subgroups(low-,medium-,and high-risk)according to gestational week and risk factors.Propensity score matching(PSM)was performed to balance the data before treatment.Study outcomes included the development of bilirubin encephalopathy,duration of hospitalization,expenses,and complications.Mortality,auditory complications,seizures,enamel dysplasia,ocular motility disorders,athetosis,motor,and language development were evaluated during follow-up at age of 3 years.Results:A total of 1164 patients were included in this study.After PSM,296 patients in the IPT only group and 296 patients in the IPT plus ET group were further divided into the low-,medium-,and high-risk subgroups with 188,364,and 40 matched patients,respectively.No significant differences were found between the IPT only and IPT plus ET groups in terms of morbidity,complications,and sequelae.Hospitalization duration and expenses were lower in the low-and medium-risk subgroups in the IPT only group.Conclusions:In this study,our results suggest that IPT is a safe and effective treatment for extreme hyperbilirubinemia.The indication of ET for patients with hyperbilirubinemia could be stricter.However,it is necessary to have a contingency plan for emergency ET as soon as IPT is commenced especially for infants with risk factors.If IPT can be guaranteed and proved to be therapeutic,ET should be avoided as much as possible. | Meng Zhang Yang He Jun Tang Wenbin Dong Yong Zhang Benjin Zhang Hong Wan Quanmin Deng Lirong Guan Bin Xia Zhong Chen Min Ge Jing Zhao Wenxing Li Jingjun Pei Yi Qu Dezhi Mu | 2022 | Chinese Medical Journal2022，，5： | 7 |
| 4 | Natural vegetation restoration of Liaodong oak(Quercus liaotungensis Koidz.) forests rapidly increased the content and ratio of inert carbon in soil macroaggregates显示文摘The lack of clarity of how natural vegetation restoration influences soil organic carbon(SOC) content and SOC components in soil aggregate fractions limits the understanding of SOC sequestration and turnover in forest ecosystems.The aim of this study was to explore how natural vegetation restoration affects the SOC content and ratio of SOC components in soil macroaggregates(>250 μm), microaggregates(53–250 μm), and silt and clay(<53 μm) fractions in 30-, 60-, 90-and 120-year-old Liaodong oak(Quercus liaotungensis Koidz.) forests, Shaanxi, China in 2015.And the associated effects of biomasses of leaf litter and different sizes of roots(0–0.5, 0.5–1.0, 1.0–2.0 and >2.0 mm diameter) on SOC components were studied too.Results showed that the contents of high activated carbon(HAC), activated carbon(AC) and inert carbon(IC) in the macroaggregates, microaggregates and silt and clay fractions increased with restoration ages.Moreover, IC content in the microaggregates in topsoil(0–20 cm) rapidly increased;peaking in the 90-year-old restored forest, and was 5.74 times higher than AC content.In deep soil(20–80 cm), IC content was 3.58 times that of AC content.Biomasses of 0.5–1.0 mm diameter roots and leaf litter affected the content of aggregate fractions in topsoil, while the biomass of >2.0 mm diameter roots affected the content of aggregate fractions in deep soil.Across the soil profiles, macroaggregates had the highest capacity for HAC sequestration.The effects of restoration ages on soil aggregate fractions and SOC content were less in deep soil than in topsoil.In conclusion, natural vegetation restoration of Liaodong oak forests improved the contents of SOC, especially IC within topsoil and deep soil.The influence of IC on aggregate stability was greater than the other SOC components, and the aggregate stability was significantly affected by the biomasses of litter, 0.5–1.0 mm diameter roots in topsoil and >2.0 mm diameter roots in deep soil.Natural vegetation restoration of Liaodong oak forests promoted SOC sequestration by soil macroaggregates. | SUN Lipeng HE Lirong WANG Guoliang JING Hang LIU Guobin | 2019 | Journal of Arid Land2019，11，6： | 5 |
| 5 | The soil configuration on granite residuals affects Benggang erosion by altering the soil water regime on the slope显示文摘A permanent collapsing gully,locally called Benggang,formed on slopes with deep granite red soil and is a type of unique gully erosion widely prevalent in southern China.Three different soil configurations(SC),ie,red-transition-sandy(SC I,the transition is the soil layer between the red soil and the sandy soil layer),transition-sandy(SC II)or sandy(SC III)are usually present in the soil profile of the Benggang slope.However,little attention has been paid to impacts of SCs on the triggering of Benggang erosion.In this study,we aimed to explore the relationships between soil water content(SWC)and triggering of Benggang erosion under different SC conditions.The soil properties of different soil layers were measured and the SWC at depths of 20,40,60,and 80 cm were monitored at 5-min intervals along a typical Benggang(SC I)during 2016-2018.The SWC of Benggang slopes with different SCs were simulated by VADOSE/W model.Results showed that the red soil layer had a higher water retention capacity and shear strength than the sandy soil layer.Even if the SWC is higher(e.g.,0.42 cm^(3)/cm^(3))at red soil layer or transition layer,the corresponding shear strength is greater than that of sandy soil layer with a lower SWC(e.g.,032 cm^(3)/cm^(3)).Relationships between shear strength and SWC of different soil layers indicate that Benggang erosion is triggered by an increase in the SWC in the deep sandy layer.Results also showed that differences exist in the SWC distribution among the different SCs.The SWC is higher in topsoil than in deeper soil in SC I and SC II,while in SC III,the opposite trend is observed.These results revealed that the presence of the red soil or transition layer can reduce the infiltration of rainwater into the deep sandy layer,thus can reduce the possibility of collapse.Our results show that the SC affects the stability of the headwall,and results provide great significances to guide the mitigation of Benggang erosion. | Xiaoqian Duan Yusong Deng Yu Tao Yangbo He Lirong Lin Jiazhou Chen | 2021 | International Soil and Water Conservation Research2021，9，3： | 4 |
| 6 | Interferon as a Mucosal Adjuvant for an Influenza Vaccine in Pigs显示文摘Interferon,a natural protein that is produced by a variety of cells during viral infection,activates the transcription of multiple functional genes in cells,regulates synergy among various signaling pathways,and mediates many biological functions such as antiviral activity,immune regulation,and cell growth.However,clinical research on interferon in livestock is lacking.In this study,recombinant porcine interferon(PoIFNα)was used as an adjuvant,in combination with inactivated influenza virus,to vaccinate 6-week-old pigs via nasal infusion.The transcription of target genes was then monitored and the functions of PoIFNαwere determined with respect to the activation of mucosal immunity.We found that a combination of low-dose PoIFNαand in activated influenza virus could significantly up-regulate the expression of immunoregulatory cytokines such as IL-2,IL-1β,IFN-γ,IL-6,and IL-10 by real-time PCR,suggesting the induction of a strong mucosal innate immune response after administration.In addition,low-dose PoIFNαcan significant enhancing the transcription of genes encoding homing factors including CCR9 and CCR10(P<0.001),thereby resulting in the induction of higher levels of HA-specific antibodies(P<0.05),which can be determined by ELISA and IFA.Post-immunization challenges with H1N1 virus demonstrated that PoIFNot,combined with inactivated influenza virus,could alleviate clinical signs in pigs during the early stages of viral infection.These studies reveal low-dose PoIFNαas a potential mucosal adjuvant for influenza virus in pigs. | Lirong Liu Wenhui Fan He Zhang Shuang Zhang Liang Cui Meng Wang Xiaoyuan Bai Wenxian Yang Lei Sun Limin Yang Wenjun Liu Jing Li | 2019 | Virologica Sinica2019，34，3： | 3 |
| 7 | Uniform single atomic Cu_(1)-C_(4)sites anchored in graphdiyne for hydroxylation of benzene to phenol显示文摘For single-atom catalysts(SACs),the catalyst supports are not only anchors for single atoms,but also modulators for geometric and electronic structures,which determine their catalytic performance.Selecting an appropriate support to prepare SACs with uniform coordination environments is critical for achieving optimal performance and clarifying the relationship between the structure and the property of SACs.Approaching such a goal is still a significant challenge.Taking advantage of the strong d-πinteraction between Cu atoms and diacetylenic in a graphdiyne(GDY)support,we present an efficient and simple strategy for fabricating Cu single atoms anchored on GDY(Cu_(1)/GDY)with uniform Cu_(1)-C_(4)single sites under mild conditions.The Cu atomic structure was confirmed by combining synchrotron radiation X-ray absorption spectroscopy,X-ray photoele ctron spectroscopy and density functional theory(DFT)calculations.The as-prepared Cu1/GDY exhibits much higher activity than state-of-the-art SACs in direct benzene oxidation to phenol with H_(2)O_(2)reaction,with turnover frequency values of 251 h^(-1)at room temperature and 1889 h^(-1)at 60℃,respectively.Furthermore,even with a high benzene conversion of86%,high phenol sele ctivity(96%)is maintaine d,which can be ascribed to the hydrophobic and oleophyllic surface nature of Cu1/GDY for benzene adsorption and phenol desorption.Both experiments and DFT calculations indicate that Cu_(1)-C_(4)single sites are more effective at activating H_(2)O_(2)to form Cu=O bonds,which are important active intermediates for benzene oxidation to phenol. | Jia Yu Changyan Cao Hongqiang Jin Weiming Chen Qikai Shen Peipei Li Lirong Zheng Feng He Weiguo Song Yuliang Li | 2022 | National Science Review2022，9，9： | 3 |
| 8 | Numerical investigation of airborne transmission of respiratory infections on the subway platform显示文摘Underground subway platforms are among the world’s busiest public transportation systems,but the airborne transmission mechanism of respiratory infections on these platforms has been rarely studied.Here,computational fluid dynamics(CFD)modeling is used to investigate the airflow patterns and infection risks in an island platform under two common ventilation modes:Mode 1-both sides have air inlets and outlets;Mode 2-air inlets are present at the two sides and outlets are present in the middle.Under the investigated scenario,airflow structure is characterized by the ventilation jet and human thermal plumes.Their interaction with the infector’s breathing jet imposes the front passenger under the highest exposure risk by short-range airborne route,with intake fractions up to 2.57%(oral breathing)or 0.63%(nasal breathing)under Mode 1;oral breathing of the infector may impose higher risks for the front passenger compared with nasal breathing.Pathogen are efficiently diluted as they travel further,in particular to adjacent crowds.The maximum and median value of intake fractions of passengers in adjacent crowds are respectively 0.093%and 0.016%(oral breathing),and 0.073%and 0.014%(nasal breathing)under Mode 1.Compared with Mode 1,the 2nd mode minimizes the interaction of ventilation jet and breathing jet,where the maximum intake fraction is only 0.34%,and the median value in the same crowd and other crowds are reduced by 23–63%.Combining published quanta generation rate data of COVID-19 and influenza infectors,the predicted maximum and median infection risks for passengers in the same crowds are respectively 1.46%–40.23%and 0.038%–1.67%during the 3–10 min waiting period,which are more sensitive to ventilation rate and exposure time compared with return air.This study can provide practical guidance for the prevention of respiratory infections in subway platforms. | Jianjian Wei Sirui Zhu Feiwu He Qianfang Guo Xinxin Huang Jianxiang Yu Lirong Zou Tao Jin Jie Wu | 2022 | Geoscience Frontiers2022，13，6： | 2 |
| 9 | Captive Breeding of the Four-eyed Turtle(Sacalia quadriocellata)显示文摘In 1998,a study on forty-five four-eyed turtles(Sacalia quadriocellata) was initiated to gather preliminary biological data of this species and to investigate the feasibility of its captive reproduction.In the following six years,no courtship behavior was found occurring in males and no oviposition in females.From 2004 to 2007,two successful techniques were applied to initiate reproductive behavior:1) injecting exogenous reproductive hormones;and 2) reducing the stress of living in captivity.As a result of the hormone treatments,courtship behavior and copulation were observed during September and October,2005.However,no courtship displays were seen from the CK males,which were not treated with hormones.Ovulation occurred between December and March,and the correlation was not significant between behavior of ovulation and food intake.Females laid only one clutch of eggs each year,with 2.47 eggs(n=34,range=1–4) at average,and 84 eggs were totally obtained,of which 13 were damaged,52 were infertile and 19 fertile.Of the fertile eggs,nine were hatched with mean incubation period of 105.9 days(n=9,range=89–122 days) at temperature ranging from 24 to 27℃. | HE Bin LIU Yuxiang SHI Haitao ZHANG Jie HU Maogui MA Yonggang FU Lirong HONG Meiling WANG Jichao Fong J.Jonathan Parham F.James | 2010 | Asian Herpetological Research2010，1，2： | 2 |
| 10 | Exposure to hazardous volatile organic compounds, PMx0 and CO while walking along streets in urban Guangzhou, China 显示文摘 | ZHAO Lirong WANG Xinming HE Qiusheng | 2004 | Atmos Environ2004，38，36： | 1 |
| 11 | Gene therapy for cancer through adenovirus vectormediated expression of the Ad5 early re- gion gene 1A based on loss of IGF2 imprinting显示文摘 | PAN Y HE B LIRONG Z | 2013 | Oncol Rep2013，30，4： | 1 |
| 12 | Diffusionless-Like Transformation Unlocks Pseudocapacitance with Bulk Utilization: Reinventing Fe_(2)O_(3) in Alkaline Electrolyte显示文摘Energy density can be substantially raised and even maximized if the bulk of an electrode material is fully utilized.Transition metal oxides based on conversion reaction mechanism are the imperative choice due to either constructing nanostructure or intercalation pseudocapacitance with their intrinsic limitations.However,the fully bulk utilization of transition metal oxides is hindered by the poor understanding of atomic-level conversion reaction mechanism,particularly it is largely missing at clarifying how the phase transformation(conversion reaction)determines the electrochemical performance such as power density and cyclic stability.Herein,α-Fe_(2)O_(3) is a case provided to claim how the diffusional and diffusionless transformation determine the electrochemical behaviors,as of its conversion reaction mechanism with fully bulk utilization in alkaline electrolyte.Specifically,the discharge productα-FeOOH diffusional from Fe(OH)2 is structurally identified as the atomic-level arch criminal for its cyclic stability deterioration,whereas the counterpartδ-FeOOH is theoretically diffusionless-like,unlocking the full potential of the pseudocapacitance with fully bulk utilization.Thus,such pseudocapacitance,in proof-of-concept and termed as conversion pseudocapacitance,is achieved via diffusionless-like transformation.This work not only provides an atomic-level perspective to reassess the potential electrochemical performance of the transition metal oxides electrode materials based on conversion reaction mechanism but also debuts a new paradigm for pseudocapacitance. | Taowen Dong Wencai Yi Ting Deng Tingting Qin Xianyu Chu He Yang Lirong Zheng Seung Jo Yoo Jin-Gyu Kim Zizhun Wang Yan Wang Wei Zhang Weitao Zheng | 2023 | Energy & Environmental Materials2023，6，1： | 1 |
| 13 | Jigsaw-like mini-pillar platform for multi-mode biosensing显示文摘The multiple sensing provides booming options to eliminate interference and ensure the accuracy of detection by mutually coupling and validating multiple data sets.Here,we integrate the jigsaw-like multifunctional mini-pillar platform to perform multi-mode(electrochemical,fluorescence,surface-enhanced Raman scattering(SERS)and colorimetric)sensing in individual microdroplets.Each mini-pillar connector can parallelize together by specific concave-convex interface to form integrated jigsaw-like platform for multi-mode sensing,and each specific mini-pillar can be modified into the individual sensing unit to read the prescribed signals.We successfully implemented electrochemical,fluorescence,SERS and colorimetric detection by multiple signals coupling to reduce the false positive analysis.Such platform brings a promising clue of in-situ analysis and point-of-care testing for disease diagnosis and health monitoring. | Yongchao Song Dongdong Wang Zehua Li Lirong Wang Chuan Fan Xuecheng He Tailin Xu Xueji Zhang | 2022 | Chinese Chemical Letters2022，33，8： | 1 |
| 14 | Modification of collagen with a natural cross-linker,procyanidin显示文摘 | He Lirong Mu Changdao Shi Jiabo | 2011 | International Journal of Biological Macromolecules2011，48，： | 1 |
| 15 | Effects of in- duction/inhibition of endogenous heme oxygenase-lon lip- id metabolism, endothelial function, and atherosclerosis in rabbits on a high fat die 显示文摘 | Danan Liu Zuoyun He Lirong Wu | 2012 | Journal of Pharmacologi- cal Sciences2012，，118： | 1 |
| 16 | Application of a polycapillary x-ray optics in high pressure XAFS显示文摘 | Yude Li Xiaoyan Lin Shigang Liu Lirong Zheng Jinlong He Fei Guo Tianxi Sun | 2013 | Journal of Optics2013，，7： | 1 |
| 17 | Selective catalytic reduction of NO with NH3 over iron titanate catalyst: catalytic performance and characterization 显示文摘 | Liu Fudong He Hong Zhang Changbin Feng Zhaochi Zheng Lirong Xie Yaning Hu Tiandou | 2010 | Applied CatalysisB: Environmental2010，96，34： | 1 |
| 18 | Exposure to hazardous volatile organic compounds,PM10 and CO while walking along streets in urban Guangzhou,China显示文摘 | Zhao Lirong Wang Xinming He Qiusheng | | 0，，36： | 1 |
| 19 | Expo- sure to hazardous volatile organic compounds, PMl0 and CO while walking along streets in urban Guangzhou, China显示文摘 | ZHAO Lirong WANG Xinning HE Qiusheng | 2004 | Atmospheric Environment2004，38，36： | 1 |
| 20 | In situ FTIR spectroscopic studies of CO adsorption on electrodes of nanometer-thin layer of Pt-Ru and Pt-Pd surface alloys显示文摘CO adsorption on nanometer-thin layer of surface alloys of Pt-Ru and Pt-Pd prepared by electrochemical codeposition has been studied using in situ FTIR spectroscopy. Abnormal infrared effects (AIREs) that consist of the enhancement of IR absorption by adsorbed CO on different surface sites and the inversion of IR band direction have been observed on the thin-layer prepared. The results also demonstrate the considerable significance of Pt-Ru and Pt-Pd surface alloys in electrocatalysis applications. | Guoqiang Lu Lirong Cai Shigang Sun Junxiang He | 1999 | Chinese Science Bulletin1999，44，16： | 1 |
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