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| 1 | Application of retrievable Solitaire AB stents in the endovascular treatment of acute ischemic stroke显示文摘Purpose: Retrievable stents are widely used in acute ischemic stroke(AIS); however, the results remain unclear in Chinese patients. This study aimed to explore the usefulness of Solitaire AB stents in AIS. Materials and Methods: Seventy-three AIS patients treated with Solitaire AB stents for thrombectomy of large artery occlusion of anterior circulation in January 2014-June 2015 were retrospectively evaluated. Recanalization was assessed with the Thrombolysis In Cerebral Ischemia(TICI) scale. Clinical outcomes were assessed according to the National Institute of Health Stroke Scale(NIHSS) and the modified Rankin Scale(mRS). Operation-related complications were recorded. The main factors affecting successful recanalization with Solitaire AB were analyzed. Results: The 73 patients enrolled included 39 males and 34 females(median age of 59 [31-78] years); 77 Solitaire AB stents were used. The initial recanalization rate with Solitaire AB as the first thrombectomy method was 53.42%(39/73; recanalization group). Among the 34 patients with failed stent retrieval, 32 underwent other treatments; the final arterial recanalization rate was 89.04%(65/73). Perioperative embolization events and symptomatic intracranial hemorrhage(sICH) occurred in 5 and 8 patients, respectively. The mean NIHSS score was 9.12±3.86 one week after thrombectomy, significantly lower compared with admission values. In 31 patients(42.47%), NIHSS score decreased by >8. Good functional independence(mRS score≤2) was achieved in 39 patients(53.42%) at 90 days; 12 patients(16.44%) died. Compared with the recanalization group, the remaining patients showed lower AF and higher LAA percentages. Conclusion: Solitaire AB stents are useful in the endovascular treatment of AIS. | Teng-Fei Zhou Liang-Fu Zhu Tian-Xiao Li Zi-Liang Wang Wei-Xing Bai Jiang-Yu Xue Guang Feng Li Li Ying-Kun He Li-Heng Wu Bu-Lang Gao | 2018 | Journal of Interventional Medicine2018，1，2： | 21 |
| 2 | The Impact of Haze Weather on Health: A view to Future显示文摘In January 2013,China suffered large-scale haze weather four times,affecting 30 cities in all.The average number of haze weather days in many regions was higher than the same period in every year since 1961.PM2.5,which is defined as fine particulate matter with an aerodynamic diameter of2.5 micrometers or less,is the main health hazard in the context of haze weather.It can carry large amounts of poisonous and harmful substances,and penetrate deep into the lungs and blood circulation through the respiratory tract,thereby affecting human health.The Global Burden of Disease Study 2010 | LU Kai QIN Yu HE Guang Xue George F.GAO | 2013 | Biomedical and Environmental Sciences2013，26，12： | 15 |
| 3 | Transformation of surface water and groundwater and water balance in the agricultural irrigation area of the Manas River Basin,China显示文摘Calculation of the water balance is very important to relieve the pressure on water resources in arid agricultural irrigation areas.This research focused on irrigation water balance calculations in the Manas River Basin of the southern margin of the Junggar Basin of China,and aimed to analyze the groundwater level dynamic trend and response characteristics of the basin water cycle under water-saving irrigation measures.The surface water and groundwater coupling model of MIKE 11-Visual MODFLOW was used to simulate rainfall runoff in mountainous areas,and quantify the contribution of water balance components in the plain irrigation area.Convergence of the delayed watershed in the mountain area was obvious,and when the river runoff exceeded 200 m^(3)/s,the error in the runoff simulation was large.The water balance in the plain agricultural irrigation area was in a negative equilibrium state,and the difference between recharge and discharge was−2.65 billion m^(3).The evapotranspiration was 24.49 billion m^(3) under drip irrigation,accounting for only approximately 51%of the total discharge.The lateral discharge of the unsaturated and saturated aquifers was 15.38 billion m^(3),accounting for approximately 32%of the total discharge.The main reason for the groundwater decline in the irrigation area was closely related to the extraction of groundwater,because the amount of recharge and discharge in the natural state was approximately identical.The MIKE 11-Visual MODFLOW model produced accurate results,and the research method provided a new exploration technique to quantify the effect of water supply mode on the groundwater table.The model is suitable for the management of water resources in arid areas. | Yang Guang He Xinlin Li Xiaolong Long Aihua Xue Lianqing | 2017 | International Journal of Agricultural and Biological Engineering2017，10，4： | 10 |
| 4 | The Lyman-alpha Solar Telescope(LST) for the ASO-S mission——Ⅱ. design of LST显示文摘As one of the three payloads for the Advanced Space-based Solar Observatory(ASO-S)mission,the Lyman-alpha(Lyα)Solar Telescope(LST)is composed of three instruments:a Solar Corona Imager(SCI),a LyαSolar Disk Imager(SDI)and a full-disk White-light Solar Telescope(WST).When working in-orbit,LST will simultaneously perform high-resolution imaging observations of all regions from the solar disk to the inner corona up to 2.5 R⊙(R⊙stands for the mean solar radius)with a spatial resolution of 4.8′′and 1.2′′for coronal and disk observations,respectively,and a temporal resolution of 30–120 s and 1–120 s for coronal and disk observations,respectively.The maximum exposure time can be up to20 s due to precise pointing and image stabilization function.Among the three telescopes of LST,SCI is a dual-waveband coronagraph simultaneously and independently observing the inner corona in the HI Lyα(121.6±10 nm)line and white light(WL)(700±40 nm)wavebands by using a narrowband Lyαbeam splitter and has a field of view(FOV)from 1.1 to 2.5 R⊙.The stray-light suppression level can attain<10^-6 B⊙(B⊙is the mean brightness of the solar disk)at 1.1 R⊙and≤5×10^-8 B⊙at 2.5 R⊙.SDI and WST are solar disk imagers working in the Lyαline and 360.0 nm wavebands,respectively,which adopt an off-axis two-mirror reflective structure with an FOV up to 1.2 R⊙,covering the inner coronal edge area and relating to coronal imaging.We present the up-to-date design for the LST payload. | Bo Chen Hui Li Ke-Fei Song Quan-Feng Guo Pei-Jie Zhang Ling-Ping He Shuang Dai Xiao-Dong Wang Hai-Feng Wang Chun-Long Liu Hong-Ji Zhang Guang Zhang Yunqi Wang Shi-Jie Liu Hong-Xin Zhang Lei Liu Shi-Lei Mao Yang Liu Jia-Hao Peng Peng Wang Liang Sun Yang Liu Zhen-Wei Han Yan-Long Wang Kun Wu Guang-Xing Ding Peng Zhou Xin Zheng Ming-Yi Xia Qing-Wen Wu Jin-Jiang Xie Ya Chen Shu-Mei Song Hong Wang Bo Zhu Chang-Bo Chu Wen-Gang Yang Li Feng Yu Huang Wei-Qun Gan Ying Li Jing-Wei Li Lei Lu Jian-Chao Xue Bei-Li Ying Ming-Zhe Sun Cheng Zhu Wei-Min Bao Lei Deng Zeng-Shan Yin | 2019 | Research in Astronomy and Astrophysics2019，19，11： | 6 |
| 5 | Atomically Smooth Ultrathin Films of Topological Insulator Sb_(2)Te_(3)显示文摘The growth and characterization of single-crystalline thin films of topological insulators(TIs)is an important step towards their possible applications.Using in situ scanning tunneling microscopy(STM)and angle-resolved photoemission spectroscopy(ARPES),we show that moderately thick Sb_(2)Te_(3)films grown layer-by-layer by molecular beam epitaxy(MBE)on Si(111)are atomically smooth,single-crystalline,and intrinsically insulating.Furthermore,these films were found to exhibit a robust TI electronic structure with their Fermi energy lying within the energy gap of the bulk that intersects only the Dirac cone of the surface states.Depositing Cs in situ moves the Fermi energy of the Sb_(2)Te_(3)films without changing the electronic band structure,as predicted by theory.We found that the TI behavior is preserved in Sb_(2)Te_(3)films down to five quintuple layers(QLs). | Guang Wang Xiegang Zhu Jing Wen Xi Chen Ke He Lili Wang Xucun Ma Ying Liu Xi Dai Zhong Fang Jinfeng Jia Qikun Xue | 2010 | Nano Research2010，3，12： | 5 |
| 6 | Comparing the Genotype and Drug Susceptibilities between Mycobacterium avium and Mycobacterium intracellulare in China显示文摘Objective Mycobacterium avium(M. avium) and Mycobacterium intracellulare(M. intracellulare) are the major causative agents of nontuberculous mycobacteria(NTM)-related pulmonary infections. However, little is known about the differences in drug susceptibility profiles between these two species. Methods A total of 393 NTM isolates were collected from Shanghai Pulmonary Disease Hospital. Sequencing of partial genes was performed to identify the strains at species level. The minimum inhibitory concentration(MIC) was used to evaluate the drug susceptibility against 20 antimicrobial agents. Variable number of tandem repeat(VNTR) typing was conducted to genotype these two species. Results A total of 173(44.0%) M. avium complex(MAC) isolates were identified, including 41(10.4%) M. avium isolates and 132(33.6%) M. intracellulare isolates. Clarithromycin and amikacin were the two most effective agents against MAC isolates. The Hunter-Gaston Discriminatory Index(HGDI) values for VNTR typing of M. avium and M. intracellulare isolates were 0.993 and 0.995, respectively. Levofloxacin resistance was more common among the unclustered strains than among the clustered strains of M. intracellulare. Conclusion M. intracellulare was the most common NTM species in China. Clarithromycin and amikacin had high antimicrobial activities against MAC. VNTR typing of MAC isolates revealed a high discriminatory power. Levofloxacin resistance was associated with unclustered strains of M. intracellulare. | ZHENG Hui Wen PANG Yu HE Guang Xue SONG Yuan Yuan ZHAO Yan Lin | 2017 | Biomedical and Environmental Sciences2017，30，7： | 4 |
| 7 | Follow-up Study of Retreatment TB Patients with Sputum Smear and/or Culture Positive Two Years after They were Declared Cured with First-line Anti-TB Drugs in Shandong Province显示文摘This study aimed to learn the recurrence rate in the retreatment TB patients with sputum smear and/or culture positive(ss+and/or c+)two years after they were declared cured,and to explore causes of recurrence in order to improve long-time treatment outcome.5 cities were selected as research locations.Recurrence of TB was judged by chest X-ray examination together with sputum smear and culture examination.Questionnaire | LI Fang SONG Chun Yan ZHAO Fei LIANG Ming Li LIU Zhi Min GUO Xiao Yan WANG Yu HE Guang Xue | 2015 | Biomedical and Environmental Sciences2015，28，2： | 3 |
| 8 | Epidemiological Characteristics of Notifiable Infectious Diseases among Foreign Cases in China,2004–2017显示文摘Objective We aimed to assess the features of notifiable infectious diseases found commonly in foreign nationals in China between 2004 and 2017 to improve public health policy and responses for infectious diseases.Methods We performed a descriptive study of notifiable infectious diseases among foreigners reported from 2004 to 2017 in China using data from the Chinese National Notifiable Infectious Disease Reporting System(NNIDRIS). Demographic, temporal-spatial distribution were described and analyzed.Results A total of 67,939 cases of 33 different infectious diseases were reported among foreigners.These diseases were seen in 31 provinces of China and originated from 146 countries of the world. The infectious diseases with the highest incidence number were human immunodeficiency virus(HIV) of18,713 cases, hepatitis B(6,461 cases), hand, foot, and mouth disease(6,327 cases). Yunnan province had the highest number of notifiable infectious diseases in foreigners. There were different trends of the major infectious diseases among foreign cases seen in China and varied among provinces.Conclusions This is the first description of the epidemiological characteristic of notifiable infectious diseases among foreigners in China from 2004 to 2017. These data can be used to better inform policymakers about national health priorities for future research and control strategies. | WU Yue LI Zhen Jun YU Shi Cheng CHEN Liang WANG Ji Chun QIN Yu SONG Yu Dan George F.GAO DONG Xiao Ping WANG Li Ping ZHANG Qun HE Guang Xue | 2020 | Biomedical and Environmental Sciences2020，33，6： | 3 |
| 9 | Antimicrobial Susceptibility Testing and Molecular Characterization of Mycobacterium fortuitum Isolates in China显示文摘We performed molecular identification of clinical isolates of Mycobacterium fortuitum(M. fortuitum) and conducted drug susceptibility testing to analyze the in vitro susceptibility of clinical M. fortuitum isolates and potential molecular mechanism conferring resistance to fluoroquinolone and macrolide drugs. The results showed that moxifloxacin had the highest in vitro activity against M. fortuitum, and most M. fortuitum isolates were resistant to clarithromycin and linezolid in China. The loss of genetic mutation in clarithromycin-and amikacin-resistant isolates indicates that some other intrinsic mechanism conferring clarithromycin and amikacin resistance plays an essential role in M. fortuitum infection. | ZHENG Hui Wen PANG Yu HE Guang Xue SONG Yuan Yuan ZHAO Yan Lin | 2017 | Biomedical and Environmental Sciences2017，30，5： | 2 |
| 10 | Prevalence of Tuberculosis among Close Contacts of Index Cases in 27 Universities in Beijing,China,2017-2018显示文摘The World Health Organization(WHO)launched the‘End TB Strategy’,which aims to reduce the mortality and incidence rate of tuberculosis(TB)by 95% and 90% by 2035,respectively,compared with the levels in 2015.To achieve these targets and milestones,the strategy set three pillars and 10 indicators,one of which is systematic screening of contacts and high-risk groups[1]. | ZHAO Fei ZHANG Zhi Guo MA Shu Bo YANG Zhen HE Yan Ping WANG Lu Qin OWITI Philip MA Chao LI Tao DU Xin ZHANG Can You CHENG Jun WANG Li Xia HE Guang Xue ZHANG Hui LI Ke Xin | 2020 | Biomedical and Environmental Sciences2020，33，10： | 2 |
| 11 | Genetic Diversity and Drug Susceptibility of Mycobacterium tuberculosis Isolates in a Remote Mountain Area of China显示文摘Objective We determined the genetic diversity of Mycobacterium tuberculosis(MTB) in a remote mountainous area of southwest China and evaluated the resolving ability of single nucleotide polymorphism(SNP) genotyping combined with variable number tandem repeat(VNTR) genotyping for Beijing family strains in association with drug resistance status.Methods Three hundred thirty-one MTB strains were isolated from patients living in mountainous regions of southwest China,and 8-loci SNP,VNTR-15 genotyping assays,and drug susceptibility testing of 9 drugs were performed.Results A total of 183 [55.29%(183/331)] strains were classified into the Beijing family.Of the 183 strains,111(60.66%) were defined as modern Beijing strains.The most predominant modern Beijing sub-lineage and ancient Beijing sub-lineage were Bmyc10 [39.34%(72/183)] and Bmyc25 [20.77%(38/183)],respectively.Of the isolates,19.64%(65/331) were resistant to at least 1 of the 9 anti-TB drugs and 17 [4.98%(17/331)] MTB isolates were multi-drug resistant tuberculosis(MDR-TB).Two hundred sixty-one isolates showed a clustering rate of 14.18%(37/261) and a discriminatory index of 0.9990.The Beijing lineage exhibited a significantly higher prevalence of MDR-TB,as well as resistance to isoniazid(INH),rifampin(RIF),and para-aminosalicylic acid(PAS) when analyzed independently(P = 0.005,P = 0.017,P = 0.014,and P = 0.006 respectively).The Beijing lineage was not associated with genetic clustering or resistance to any drug.In addition,genetic clustering was not associated with drug resistance.Conclusion MTB strains demonstrate high genetic diversity in remote mountainous areas of southwest China.Beijing strains,especially modern Beijing strains,are predominant in remote mountainous area of China.The combination of 8-loci SNPs and VNTR-15 genotyping is a useful tool to study the molecular epidemiology of MTB strains in this area. | ma ai jing wang sheng fen fan jia le zhao bing he guang xue zhao yan lin | 2018 | Biomedical and Environmental Sciences2018，31，5： | 2 |
| 12 | The Current Status and Challenges Regarding Tuberculosis Infection Control in Health Care Facilities in China显示文摘Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis(TB).The TB prevention and treatment staff in health care facilities are responsible for the identification,diagnosis,treatment,supervision,and management of | ZHAO Fei CHENG Jun CHENG Shi Ming ZHANG Hui ZHAO Yan Lin ZHANG Can You HU Dong Mei FAN Hai Ying HUANG Fei QU Yan HE Guang Xue WANG Li Xia | 2015 | Biomedical and Environmental Sciences2015，28，11： | 2 |
| 13 | Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘 | Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia | 2012 | Glob Change Biol2012，，3： | 1 |
| 14 | The performance of BAF using natural zeolite as filter media under conditions of low tempe- rature and ammonium shock load显示文摘 | He Shengbing Xue Guang Kong Hainan | 2007 | Journal of Hazardous Materials2007，143，12： | 1 |
| 15 | Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘 | Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia | 2012 | Glob Change Biol2012，，3： | 1 |
| 16 | Superconductivity in One-atomic-layer Metal Films显示文摘Superconductivity is a peculiar quantum phenomenon which originates from the pairing of conduction electrons, followed by phase coherent condensation. Since the discovery by K. Onnes in 1911, superconductivity has been one of the hottest topics in physics for an entire century, and still attracts people's great interest. One of the intriguing issues is | ZHANG Tong CHENG Peng LI Wenjuan SUN Yujie WANG Guang ZHU Xiegang HE Ke WANG Lili MA Xucun CHEN Xi WANG Yayu LIU Ying LIN Haiqing JIA Jinfeng XUE Qikun | 2011 | Bulletin of the Chinese Academy of Sciences2011，25，4： | 1 |
| 17 | Effects of timing and duration under brackish water mulch drip irrigation on cotton yield in northern Xinjiang,China显示文摘The brackish water is an important potential water source and has frequently been utilized to drip-irrigate cotton due to the water shortage in the arid region of Xinjiang,northwestern of China.The brackish water is usually saline water with salinity ranging from 1 g/L to 5 g/L,which is widely distributed in this area,so the reasonable use of that brackish water may not only play a vital role in the local agricultural production,but also save plenty of freshwater.However,irrigation with brackish water usually causes the reduction of crop yield and soil salinization which can negatively impact plants through three major components:osmotic,nutritious and toxic stresses.Therefore,a field experiment,with eight different time-series irrigation modes using brackish water(3.5±0.2)g/L and freshwater(<1 g/L),beneath a combined film and drip-irrigation system was carried out to study the changes of soil salt content and cotton yield aiming to search for a balanced method during the 2 cotton growing seasons in 2012 and 2013.The results indicated that the time-series irrigation modes determined the soil salinity and moisture distribution based on observed spatio-temporal distribution of water content and electric conductivity,and soil salinity generally gathered at the depth of 0-10 cm and 60 cm of soil with the increase of irrigation quota.Moreover,the results demonstrated that the yields of cotton which was grown using brackish water and freshwater were better than those only using freshwater and the soil salinity with reasonable irrigation timing was not accumulated obviously. | Wang Chunxia Yang Guang Li Junfeng He Xinlin Xue Lianqing Long Aihua | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 1 |
| 18 | A 3‐year prospective study of the epidemiology of acute respiratory viral infections in hospitalized children in Shenzhen, China显示文摘 | Ying He Guang‐Yu Lin Qiong Wang Xiao‐Ying Cai Yin‐Hui Zhang Chuang‐Xing Lin Chang‐Dong Lu Xue‐Dong Lu | 2014 | Influenza Other Respi Viruses2014，，4： | 1 |
| 19 | Genotyping Characteristics of Human Fecal Escherichia coli and Their Association with Multidrug Resistance in Miyun District, Beijing显示文摘Objective To explore the genotyping characteristics of human fecal Escherichia coli(E. coli) and the relationships between antibiotic resistance genes(ARGs) and multidrug resistance(MDR) of E. coli in Miyun District, Beijing, an area with high incidence of infectious diarrheal cases but no related data.Methods Over a period of 3 years, 94 E. coli strains were isolated from fecal samples collected from Miyun District Hospital, a surveillance hospital of the National Pathogen Identification Network. The antibiotic susceptibility of the isolates was determined by the broth microdilution method. ARGs,multilocus sequence typing(MLST), and polymorphism trees were analyzed using whole-genome sequencing data(WGS).Results This study revealed that 68.09% of the isolates had MDR, prevalent and distributed in different clades, with a relatively high rate and low pathogenicity. There was no difference in MDR between the diarrheal(49/70) and healthy groups(15/24).Conclusion We developed a random forest(RF) prediction model of TEM.1 + baeR + mphA + mphB +QnrS1 + AAC.3-IId to identify MDR status, highlighting its potential for early resistance identification. The causes of MDR are likely mobile units transmitting the ARGs. In the future, we will continue to strengthen the monitoring of ARGs and MDR, and increase the number of strains to further verify the accuracy of the MDR markers. | ZHANG Wei Wei ZHU Xiao Lin DENG Le Le HAN Ya Jun LI Zhuo Wei WANG Jin Long CHEN Yong Liang WANG Ao Lin TIAN Er Li CHENG Bin XU Lin Hua CHEN Yi Cong TIAN Li Li HE Guang Xue | 2023 | Biomedical and Environmental Sciences2023，36，5： | 0 |
| 20 | Effects of Nb Addition on Charpy Impact Properties of TiVTa Refractory High‑Entropy Alloy显示文摘In the present study,the effects of Nb addition on Charpy impact properties of TiVTa refractory high-entropy alloy with high strength-ductility trade-off were systematically studied by using the instrumented Charpy impact testing machine.The experimental results showed that the impact toughness was remarkably improved by Nb addition in TiVTa to form TiVTaNb alloy.The crack initiation energy and propagation energy of TiVTaNb were 67.3%and 24.9%higher than that of TiVTa,indicating that Nb addition simultaneously reinforced the resistance to crack initiation and propagation.The impact fracture of TiVTaNb exhibited larger bending degree of shear lips,deeper dimples and more secondary cracks which effectively dissipated more impact energy.The deformation mechanism of TiVTa alloy was dominated by dislocation activities.While in TiVTaNb,the deformation mechanism was synergized by dislocation activities and deformation twinning,which were the main contributors for the improved impact properties and the stronger crack resistance of TiVTaNb alloy under impact loading. | Xue Yin Yan‑Kun Dou Xin‑Fu He Ke Jin Cheng‑Long Wang Ya‑Guang Dong Cun‑Yong Wang Yun‑Fei Xue Wen Yang | 2023 | Acta Metallurgica Sinica(English Letters)2023，36，3： | 0 |
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