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| 1 | Passive micromixer for applications in the microreactor andμTAS fields显示文摘 | HARDT S DRESE K S HESSEL F | 2005 | Microfluidics and Nanofluidics2005，1，2： | 1 |
| 2 | Immediate and chronic effects of AV delay optimization in patients with cardiac resynchronization therapy 显示文摘 | HARDT S E YAZDI S H BAUER A | 2007 | Int J Cardiol2007，115，： | 1 |
| 3 | The Spirituality Questi onnaire:Core Dimensions of Spirituality显示文摘 | Hardt J Schultz S Xander C | 2012 | Psychology2012，，3： | 1 |
| 4 | A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties 显示文摘 | Ali S S Hardt J I Quick K L Kim-Han J S Erlanger B F H uang T T | 2004 | Free Radic Biol Med2004，37，： | 1 |
| 5 | Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer)显示文摘 | Lee JS yon der Hardt S Ruseh MA | | 0，，： | 1 |
| 6 | Evaporation model for interfacial flows based on a continuum-field representation of the source terms 显示文摘 | HARDT S WONDRA F | 2008 | Journal of Computational Physics2008，227，11： | 1 |
| 7 | Faecal tumour M2 pyruvate kinase : a new, sensitive screening tool for colorectal cancer 显示文摘 | Hardt PD Mazurek S Toepler M | 2004 | Br J Cancer2004，91，5： | 1 |
| 8 | High-capacity cathodes for lithium-ion batteries from nanostructured LiFePO4 synthesized by high/y-flexible and scalable flame spray pyrolysis 显示文摘 | Hamid N A Wennig S Hardt S | 2012 | Journal of Power Sources2012，216，： | 1 |
| 9 | High-temperature fatigue damage mechanisms in near α titanium alloy IMI834显示文摘 | HARDT S MAIER H J CHRIST H J | 1999 | International Journal of Fatigue1999，21，8： | 1 |
| 10 | The proteomes of human pa-rotid and submandibular/sublingual gland salivas collected as the ductal secretions 显示文摘 | DENNY P HAGEN F K HARDT M LIAO L YAN W ARELLANNO M BASSILIAN S | 2008 | J Proteome Res2008，7，5： | 1 |
| 11 | High-temperature fatigue damage mechanisms in near-ct titanium alloy IMI 834 显示文摘 | Hardt S Maier H J Christ H J | 1999 | Interna- tional Journal of Fatigue1999，21，8： | 1 |
| 12 | Comparison of color flow Doppler sonography (CFDS) and immunohistologic detection of microvessels for the assessment of the malignancy of thyroid nodules 显示文摘 | Sancak S Hardt A Gartner A | 2010 | Horm Metab Res2010，42，9： | 1 |
| 13 | Hypothesis:Beta-adrenergic receptor blockers and weight gain:a systematic analysis显示文摘 | Sharma AM Pischon T Hardt S | 2001 | Hypertension2001，37，： | 1 |
| 14 | Helical flows and chaotic mixing in curved microchannels显示文摘 | Jiang F Drese K S Hardt S Kupper M Schonfeld F | 2004 | AIChEJournal2004，50，： | 1 |
| 15 | Effects of processing parameters on the micro-channels replication in microfluidic devices fabricated by micro injection molding显示文摘 | FuG Tor S B Hardt D E | 2011 | Microsystem Technologies2011，17，12： | 1 |
| 16 | Simulation of helical flows in microchannels 显示文摘 | SchSnfeld F Hardt S | 2004 | AIChEJournal2004，50，： | 1 |
| 17 | Helical flows and chaotic mixing in curved micro channels显示文摘 | JIANG F DRESE K S HARDT S | | 0，，9： | 1 |
| 18 | Simulation of helical flows in microchannels显示文摘 | SCHONFELD F HARDT S | | 0，，4： | 1 |
| 19 | 人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。 | J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) | 2009 | 世界临床医学2009，，12： | 1 |
| 20 | Hypothesis:Beta-adrenergic receptor blockers and weight gain:A systematic analysis显示文摘 | Sharma AM Pischon T Hardt S | 2001 | Hypertension2001，37，： | 1 |
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