| 1 | A portable X-pinch design for x-ray diagnostics of warm dense matter显示文摘We describe the design and x-ray emission properties(temporal,spatial,and spectral)of Dry Pinch I,a portable X-pinch driver developed at Imperial College London.Dry Pinch I is a direct capacitor discharge device,30033003700 mm3 in size and∼50 kg in mass,that can be used as an external driver for x-ray diagnostics in high-energy-density physics experiments.Among key findings,the device is shown to reliably produce 1.1±0.3 ns long x-ray bursts that couple∼50 mJ of energy into photon energies from 1 to 10 keV.The average shot-to-shot jitter of these bursts is found to be 10±4.6 ns using a combination of x-ray and current diagnostics.The spatial extent of the x-ray hot spot from which the radiation emanates agrees with previously published results for X-pinches-suggesting a spot size of 10±6μm in the soft energy region(1–10 keV)and 190±100μm in the hard energy region(>10 keV).These characteristics mean that Dry Pinch I is ideally suited for use as a probe in experiments driven in the laboratory or at external facilities when more conventional sources of probing radiation are not available.At the same time,this is also the first detailed investigation of an X-pinch operating reliably at current rise rates of less than 1 kA/ns. | J.Strucka J.W.D.Halliday T.Gheorghiu H.Horton B.Krawczyk P.Moloney S.Parker G.Rowland N.Schwartz S.Stanislaus S.Theocharous C.Wilson Z.Zhao T.A.Shelkovenko S.A.Pikuz S.N.Bland | 2022 | Matter and Radiation at Extremes2022，7，1： | 0 |
| 2 | C-reactive protein and telomerase reverse transcriptase(TERT)associate with chronic disease markers in a sample from low-income neighborhoods in Detroit,Michigan显示文摘Racial and ethnic minorities in economically deprived inner cities experience high rates of chronic diseases compared to neighborhoods with higher socioeconomic status(SES).However,these economically deprived populations are understudied in terms of biomarkers associated with chronic disease risk which include C-reactive protein(CRP),telomerase reverse transcriptase(TERT),and glycosylated hemoglobin(A1C).We examined relationships between CRP and TERT and chronic disease indicators(body mass index[BMI]and A1C)in two lowincome,predominantly African American(AA)neighborhoods in Detroit,Michigan.Sixty-nine adults(43 females,26 males,mean age 46 years[y],standard deviation[SD]=15.9)completed a health survey,anthropometry,and finger stick blood tests.A1C was measured using A1CNow test strips,and CRP and TERT levels were measured using enzyme-linked immunosorbent assay(ELISA)with samples extracted from dried blood spots.We examined CRP(mean=4.9,SD=3.1),TERT(mean=32.5,SD=15.1),and A1C(mean=5.4,SD=1.0)by BMI category.We fitted restricted maximum likelihood regression models to evaluate associations between CRP,TERT,BMI,and A1C,after adjustment for demographics and inclusion of a random effect for the neighborhood.In this predominantly AA sample(91%,63/69),68%had levels of CRP(means=4.8 mg/L,SD=3.0 for AAs;6.4 mg/L,SD=3.9 for all others)indicative of chronic inflammation(CRP greater than 3 mg/L).BMI was significantly associated with CRP(p=0.004)and TERT(p=0.026).TERT levels indicate that being overweight is associated with markers of chromosome remodeling,suggestive of chronic disease.CRP followed a similar trend with overweight individuals having higher inflammation and risk of chronic disease.Our findings warrant further exploration of additional factors that may influence CRP and TERT.Furthermore,examining populations in a more ethnically and/or economically diverse,yet still high proportion minority,sample will fill a knowledge gap in this understudied field. | David P.Ferguson Eric C.Leszczynski Teresa H.Horton Karin A.Pfeiffer Joseph Gardiner Amber L.Pearson | 2022 | Sports Medicine and Health Science2022，4，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员