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| 1 | Clp Protease and OR Directly Control the Proteostasis of Phytoene Synthase, the Crucial Enzyme for Carotenoid Biosynthesis in Arabidopsis显示文摘Phytoene synthase (PSY ) 是在类胡萝卜素 biosynthetic 小径的关键 plastidial 酶。然而,它的 translational 以后规定留下逃犯。同样, Clp 朊酶组成质体朊酶网络的中央部分,但是它为降级的底层不是众所周知的。在这研究,我们报导 PSY 是 Clp 朊酶的底层。PSY 被揭开身体上与各种各样的 Clp 朊酶子单元交往(即, ClpS1, ClpC1,和 ClpD ) 。在 clpc1, clpp4,和 clpr1-2 异种的 PSY 和几另外的 carotenogenic 酶蛋白质 overaccumulate 高级。overaccumulated PSY 被发现部分酶地活跃。在 clpc1 的 Clp 活动的缺陷导致 PSY 蛋白质周转的减少的率,进一步在降级的 PSY 支持 Clp 朊酶的角色蛋白质。在另一方面, ORANGE (或) 蛋白质,有 holdase 女伴活动的 PSY 的一个主要 translational 以后管理者,提高 PSY 蛋白质稳定性并且在 clpc1 增加 PSY 的酶地活跃的比例, counterbalancing 在维持 PSY 蛋白质动态平衡的调停 Clp 的解朊作用。一起,这些调查结果提供新奇卓见进质体局部性的蛋白质的质量控制并且建立迄今未辩别出的 translational 以后在在植物的 modulating 类胡萝卜素生合成的 carotenogenic 酶的规章的机制。 | Ralf Welsch Xiangjun Zhou Hui Yuan Daniel Alvarez Tianhu Sun Dennis Schlossarek Yong Yang Guoxin Shen Hong Zhang Manuel Rodriguez-Concepcion Theodore W. Thannhauser Li Li | 2018 | Molecular Plant2018，11，1： | 10 |
| 2 | Ordered mesoporous NiFe_2O_4 with ultrathin framework for low-ppb toluene sensing显示文摘Highly sensitive and selective detection against specific target gases,especially at low-ppb(part per billion)level,remain a great number of challenges in gas sensor applications.In this paper,we first present an ordered mesoporous NiFe_2O_4 for highly sensitive and selective detection against low-ppb toluene.A series of mesoporous NiFe_2O_4 materials were synthesized by templating from mesoporous silica KIT-6 and its framework thickness was reduced from 8.5 to 5 nm by varying the pore size of KIT-6 from 9.4 to 5.6 nm,accompanied with the increase of the specific surface area from 134 to 216 m^2g^(-1).The ordered mesoporous NiFe_2O_4 with both ultrathin framework of 5 nm and large specific surface area of up to 216 m^2g^(-1)exhibits a highest response(R_(gas)/R_(air)-1=77.3)toward 1,000 ppb toluene at 230℃ and is nearly 7.3 and 76.7 times higher than those for the NiFe_2O_4 replica with thick framework and its bulk counterpart respectively,which also possesses a quite low limit of detection(<2 ppb),and good selectivity. | Xiaoyong Lai Kun Cao Guoxin Shen Ping Xue Dan Wang Fang Hu Jianli Zhang Qingfeng Yang Xiaozhong Wang | 2018 | Science Bulletin2018，63，3： | 3 |
| 3 | Design and experimental performance verification of a thermal property test-bed for lunar drilling exploration显示文摘Chinese Chang'e lunar exploration project aims to collect and return subsurface lunar soil samples at a minimum penetration depth of 2 m in 2017. However, in contrast to those on the Earth, automated drilling and sampling missions on the Moon raise the risk of burning bits.Test-beds are required for testing the thermal properties of drill tools in a lunar environment. In this paper, a novel temperature measuring method based on thermocouples and a slip ring was proposed. Furthermore, a data acquisition system for a drilling process was designed. A vacuous,cryogenic, and anhydrous soil environment simulating the lunar surface was established. A drilling test-bed that can reach a depth of 2.2 m was developed. A control strategy based on online monitoring signals was proposed to improve the drilling performance. Vacuum and non-vacuum experiments were performed to test the temperature rising effect on drill tools. When compared with the non-vacuum experiment, the vacuum temperature rise resulted in a 12 °C increase. These experimental results provide significant support for Chinese lunar exploration missions. | Zhang Tao Zhao Zeng Liu Shuting Li Jinglin Ding Xilun Yin Shen Wang Guoxin Lai Xiaoming | 2016 | Chinese Journal of Aeronautics2016，29，5： | 3 |
| 4 | Influence of lunar regolith compressibility on sampling performance of thick wall spiral drills显示文摘A 2 m class robotic drill was sent to the Moon and successfully collected and returned regolith samples in late 2020 by China.It was a typical thick wall spiral drill(TWSD)with a hollow auger containing a complex coring system to retain subsurface regolith samples.Before the robotic drill was launched,a series of laboratory tests were carried out to investigate and predict the possible drilling loads it may encounter in the lunar environment.This work presents how the sampling performance of the TWSD is affected by the regolith compressibility.Experiments and analysis during the drilling and sampling process in a simulated lunar regolith environment were conducted.The compressibility of a typical lunar regolith simulant(LRS)was measured through unidirectional compression tests to study the relationship between its inner regolith stress and bulk density.A theoretical model was established to elucidate the cutting discharge behavior by auger flights based on the aforementioned relationship.Experiments were conducted with the LRS,and the results show that the sampling performance is greatly affected by the flux of the drilled cuttings into the spiral flight channels.This work helped in scheduling reasonable drilling parameters to promote the sampling performance of the robotic drill in the Chinese Chang’E 5 mission. | Yong PANG Tao ZHANG Hongyu WEI Ting ZENG Yinliang ZHANG Guidong MO Kun XU Shen YIN Guoxin WANG Xingwang ZHANG Xiaoming LAI Xilun DING | 2023 | Chinese Journal of Aeronautics2023，36，2： | 2 |
| 5 | Creating drought-and salt-tolerant cotton by overexpressing a vacuolar pyrophosphatase gene 显示文摘 | Hong Zhang Guoxin Shen Sundaram Kuppu | 2011 | Plant Signaling & Behavior2011，6，6： | 1 |
| 6 | A P2P-based Infrastructure for adaptive trustworthy and efficient communication in wide-area distributed systems显示文摘 | SHEN Haiying LIU Guoxin Gemmill J | 2014 | IEEE Transactions on Parallel and Distributed Systems2014，25，9： | 1 |
| 7 | Thermal stability, magnetic and mechanical properties of Fe–Dy–B–Nb bulk metallic glasses with high glass-forming ability显示文摘 | Jiawei Li Weiming Yang Diana Estévez Guoxin Chen Wenguang Zhao Qikui Man Yuanyun Zhao Zhidong Zhang Baolong Shen | 2014 | Intermetallics2014，，： | 1 |
| 8 | Clinical application of local ultrasound hyperthermia combined with systemic chemotherapy in oral maxillofacial-head and neck malignant tumors显示文摘 | Guoxin Ren Wei Guo Yazhu Chen Guofeng Shen Dongxia Ye Jingfeng Bai | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 1 |
| 9 | Increased levels of SLP-2 correlate with poor prognosis in gastric cancer显示文摘 | Dongning Liu Lei Zhang Zhiyong Shen Fei Tan Yanfeng Hu Jiang Yu Guoxin Li | 2013 | Gastric Cancer2013，，4： | 1 |
| 10 | Expression of an Arabidopsis vacuolar sodium/proton antiporter gene in cotton improves photosynthetic performance under salt conditions and increases fiber yield in the field显示文摘 | Cixin He Juqiang Yan Guoxin Shen | 2005 | Plant Cell Physiol2005，45，11： | 1 |
| 11 | Enhancing crop yield by using Rubisco activase to improve photosynthesis under elevated temperatures显示文摘With the rapid growth of world population,it is essential to increase agricultural productivity to feed the growing population.Over the past decades,many methods have been used to increase crop yields.Despite the success in boosting the crop yield through these methods,global food production still needs to be increased to be on par with the increasing population and its dynamic consumption patterns.Additionally,given the prevailing environmental conditions pertaining to the global temperature increase,heat stress will likely be a critical factor that negatively affects plant biomass and crop yield.One of the key elements hindering photosynthesis and plant productivity under heat stress is the thermo-sensitivity of the Rubisco activase(RCA),a molecular chaperone that converts Rubisco back to active form after it becomes inactive.It would be an attractive and practical strategy to maintain photosynthetic activity under elevated temperatures by enhancing the thermo-stability of RCA.In this context,this review discusses the need to improve the thermo-tolerance of RCA under current climatic conditions and to further study RCA structure and regulation,and its limitations at elevated temperatures.This review summarizes successful results and provides a perspective on RCA research and its implication in improving crop yield under elevated temperature conditions in the future. | Inosha Wijewardene Guoxin Shen Hong Zhang | 2021 | Stress Biology2021，1，1： | 0 |
| 12 | Physiological and Proteomic Analyses Reveal Effects of Putrescine-Alleviated Aluminum Toxicity in Rice Roots显示文摘The effects of putrescine on improving rice growth under aluminum(Al)toxicity conditions have been previously demonstrated,however,the underlying mechanism remains unclear.In this study,treatment with 50 pmol/L Al significantly decreased rice root growth and whole rice dry weight,inhibited Ca2+uptake,decreased ATP syn thesis,and in creased Al,H2O2 and malon dialdehyde(MDA)con tents,whereas the application of putrescine mitigated these negative effects.Putrescine increased root growth and total dry weight of rice,reduced total Al content,decreased H2O2 and MDA contents by increasing antioxidant enzyme(superoxide dismutase,peroxidase,catalase and glutathione S・transferase)activities,increased Ca2+uptake and energy product!oru Proteomic analyses using data-independent acquisition successfully identified 7934 proteins,and 59 representative proteins exhibiting fold-change values higher than 1.5 were randomly selected.From the results of the proteomic and biochemical analyses,we found that putrescine significantly inhibited ethylene biosynthesis and phosphorus uptake in rice roots,increased pectin methylation,decreased pectin content and apoplastic Al deposit!on in rice roots.Putrescine also alleviated Al toxicity by repairing damaged DNA and increasing the proteins involved in maintaining plasma membra ne integrity and normal cell proliferation.These fin dings improve our understanding of how putrescine affects the rice response to Al toxicity,which will facilitate further studies on environmental protection,crop safety,in novations in rice performance and real-world producti on. | ZHU Chunquan HU Wenjun CAO Xiaochuang ZHU Lianfeng KONG Yali JIN Qianyu SHEN Guoxin WANG Weipeng ZHANG Hui ZHANG Junhua | 2021 | Rice science2021，28，6： | 0 |
| 13 | Hypoglycemic mechanism of Tegillarca granosa polysaccharides on type 2 diabetic mice by altering gut microbiota and regulating the PI3K-akt signaling pathwaye显示文摘Type 2 diabetes mellitus(T2DM)is a complex metabolic disease threatening human health.We investigated the effects of Tegillarca granosa polysaccharide(TGP)and determined its potential mechanisms in a mouse model of T2DM established through a high-fat diet and streptozotocin.TGP(5.1×10^(3) Da)was composed of mannose,glucosamine,rhamnose,glucuronic acid,galactosamine,glucose,galactose,xylose,and fucose.It could significantly alleviate weight loss,reduce fasting blood glucose levels,reverse dyslipidemia,reduce liver damage from oxidative stress,and improve insulin sensitivity.RT-PCR and Western blotting indicated that TGP could activate the phosphatidylinositol-3-kinase/protein kinase B signaling pathway to regulate disorders in glucolipid metabolism and improve insulin resistance.TGP increased the abundance of Allobaculum,Akkermansia,and Bifidobacterium,restored the microbiota abundance in the intestinal tracts of mice with T2DM,and promoted short-chain fatty acid production.This study provides new insights into the antidiabetic effects of TGP and highlights its potential as a natural hypoglycemic nutraceutical. | Qihong Jiang Lin Chen Rui Wang Yin Chen Shanggui Deng Guoxin Shen Shulai Liu Xingwei Xiang | 2024 | Food Science and Human Wellness2024，13，2： | 0 |
| 14 | Early Diagnosis and Prevention of Osteodystrophy in Perinatal Cow显示文摘Hydroxyproline is the main component of collagen,accounting for 20% or so of collagen,and metabolic changes in bone collagen directly affect the level of hydroxyproline in the blood.So inspecting the content of hydroxyproline is very important for pathogenesis and prophylactico-therapeutic measures on osteodystrophy of dairy cows.This experiment monitored and studied the change regularity of serum calcium,serum phosphorus and serum free hydroxyproline of perinatal cow in Hebei Province,and discussed a new and early diagnosis way for osteodystrophy.Thus,effective control measures could be implemented before the bone became deformed without any clinical symptom.The paper provided a theoretical foundation for early diagnosis of perinatal cow. | Shen Guoxin Xue Xiaoling | 2016 | Animal Husbandry and Feed Science2016，8，3： | 0 |
| 15 | Extraction of uranium (VI) from nitric acid with N-decanoylpyrrolidine (DPOD) in toluene显示文摘The extraction behaviors of uranium (VI) from nitric acid by N-decanoylpyrrolidine (DPOD) in toluene has been studied at varying concentrations of nitric acid, extractant, salting out agent LiNO3 and at different temperatures. The mechanism of extraction is discussed in the light of the results obtained. | HAN Jingtian SUN Guoxin BAO Borong (Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences, Shanghai 201800) CHEN Shufeng SHEN Yunxiu (Binzhou Medical College, Binzhou 256603) | 1999 | Nuclear Science and Techniques1999，10，1： | 0 |
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