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4篇 您的检索式:作者名="Guo Baoxin"
    题名 作者 年代 出处 被引量
1Heavy oil component characterization with multi-dimensional unilateral NMR显示文摘Heavy oil is a complicated mixture and a potential resource and has attracted much attention since the end of last century. It is important to characterize the composition of heavy oil to enhance its recovery efficiency. A designed unilateral Nuclear Magnetic Resonance (NMR) sensor with a Larmor frequency of 20 MHz and a well-defined constant gradient of 23.25 T/m was employed to acquire three-dimensional (3D) data for three heavy oil samples. The highly-constant gradient is advantageous for diffusion coefficient measurement of heavy oil. A fast data-implementation procedure including specially designed 3D pulse sequence and Inversion Laplace Transform (ILT) algorithm was adopted to process the data and extract 3D T1-D-T2 probability function. It indicates that NMR relaxometry and diffusometry are useful to characterize the components of heavy oil samples. NMR results were compared with independent measurements of fractionation and gas chromatography analysis.Liu Huabing Xiao Lizhi Guo Baoxin Zhang Zongfu Zong Fangrong Deng Feng Yu Huijun V.Anferov S.Anferova 2013Petroleum Science2013,10,3:4
2Particle Sizes and Antibacterial Activity of Radix Astragalus and Radix Isatidis Ultrafine Powders显示文摘Using 9200 laser particle size analyzer and KYKY-2800 scanning electron microscope,particle sizes and cellular morphology of Radix Astragalus and Radix Isatidis ultrafine powders were observed. According to the results,the particle size of 89.1% of Radix Astragalus ultrafine powders ranged from 1.729 μm to 44. 938 μm,D_(50)=4.368 μm; t he particle size of 93.411% of Radix Isatidis ultrafine powders ranged from 1. 510 μm to 44. 938 μm,D50= 8.726 μm. Radix Astragalus and Radix Isatidis ultrafine powders were pulverized completely without intact cellular morphology. The antibacterial activity of Radix Astragalus and Radix Isatidis ultrafine powders against chicken-derived E. coli(O78) w as investigated. The results indicated that Radix Astragalus and Radix Isatidis ultrafine powders exhibited higher antibacterial activity against chicken-derived E. coli(O78) c ompared with the corresponding coarse powders. This study laid a solid foundation for the development and application of Chinese medicine ultrafine powder preparations.Qiumei SHI Xinhua SHAO Xiumin WANG Xia MENG Xiaoqiao HOU Baoxin YANG Leiyu GUO Jinglong GAO 2016Agricultural Biotechnology2016,5,4:1
3HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway显示文摘Chronic hepatitis B virus(HBV)infection is one of the leading causes of hepatocellular carcinoma(HCC).The HBV genome is prone to mutate and several variants are closely related to the malignant transformation of liver disease.G1896A mutation(G to A mutation at nucleotide 1896)is one of the most frequently observed mutations in the precore region of HBV,which prevents HBeAg expression and is strongly associated with HCC.However,the mechanisms by which this mutation causes HCC are unclear.Here,we explored the function and molecular mechanisms of the G1896A mutation during HBV-associated HCC.G1896A mutation remarkably enhanced the HBV replication in vitro.Moreover,it increased tumor formation and inhibited apoptosis of hepatoma cells,and decreased the sensitivity of HCC to sorafenib.Mechanistically,the G1896A mutation could activate ERK/MAPK pathway to enhanced sorafenib resistance in HCC cells and augmented cell survival and growth.Collectively,our study demonstrates for the first time that the G1896A mutation has a dual regulatory role in exacerbating HCC severity and sheds some light on the treatment of G1896A mutation-associated HCC patients.Baoxin Zhao Hongxiu Qiao Yan Zhao Zhiyun Gao Weijie Wang Yan Cui Jian Li Zhanjun Guo Xia Chuai Sandra Chiu 2023Virologica Sinica2023,38,5:0
4Steering CO_(2)electrolysis selectivity by modulating the local reaction environment:An online DEMS approach for Cu electrodes显示文摘Electrochemical CO_(2)reduction is a typical surface-mediated reaction,with its reaction kinetics and product distributions largely dependent on the dynamic evolution of reactive species at the cathode–catholyte interface and on the resultant mass transport within the hydrodynamic boundary layer in the vicinity of the cathode.To resolve the complex local reaction environment of branching CO_(2)reduction pathways,we here present a dif-ferential electrochemical mass spectroscopic(DEMS)approach for Cu electrodes to investigate CO_(2)mass trans-port,the local concentration gradients of buffering anions,and the Cu surface topology effects on CO_(2)electrolysis selectivity at a temporal resolution of~400 ms.As a proof of concept,these tuning knobs were validated on an anion exchange membrane electrolyzer,which delivered a Faradaic efficiency of up to 40.4%and a partial current density of 121 mA cm^(-2)for CO_(2)-to-C_(2)H_(4)valorization.This methodology,which bridges the study of fundamental surface electrochemistry and the upgrading of practical electrolyzer performance,could be of general interest in helping to achieve a sustainable circular carbon economy.Ke Ye Guiru Zhang Baoxin Ni Liang Guo Chengwei Deng Xiaodong Zhuang Changying Zhao Wen-Bin Cai Kun Jiang 2023eScience2023,3,4:0
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