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| 1 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019,11,2: | 2 |
| 2 | Relation- ship between chest compression rates and outcomes from cardiac arrest显示文摘 | Idris A H Guffey D Aufderheide T P | 2012 | Circulation2012,125,24: | 1 |
| 3 | Relationship between chest compression rates and outcomes from cardiac arrest显示文摘 | Idris AH Guffey D Aufderheide TP | 2012 | Circulation2012,125,24: | 1 |
| 4 | Relationshipbetween chest compression rates and outcomes from cardiac arrest显示文摘 | Idris AH Guffey D Aufderheide TP | 2012 | Circulation2012,125,24: | 1 |
| 5 | Relationship between chest compression rates and outcomes from cardiac arrest 显示文摘 | Idris AH Guffey D Aufderheide TP et 8/ | 2012 | Circulation2012,125,24: | 1 |
| 6 | Analysis of oil shale retort production stream gases for sulfur species 显示文摘 | GUFFEY F D BARBOUR F A CUMMINGS R E | 1983 | Liquid Fuels Technology1983,1,4: | 1 |
| 7 | Thermal Pretreatment of Low-ranked Coal for Control of Mercury Emissions 显示文摘 | Guffey F D Bland A E | 2004 | Fuel Process Technology2004,85,67: | 1 |
| 8 | Direct Bankruptcy Costs:Evidence from the Trucking Industry 显示文摘 | W Moore | 1991 | Financial Review1991,,26: | 1 |
| 9 | Artificial Neural Networks for Identification of Beam Pump Dynamometer Load Cards显示文摘 | Rogers J D Guffey G G Oldham W J B | | 0,,23: | 1 |
| 10 | Hypoglycaemia and hyper- glycaemia are associated with unfavourable outcome in infants with hypoxic ischaemic encephalopathy: a post hoc analysis of the CoolCap Study 显示文摘 | Basu SK Kaiser JR Guffey D | 2015 | Arch Dis Child Fetal Neonatal Ed2015,,: | 1 |
| 11 | Gender Differences in Determining the Ethical Sensitivity of Future Accounting Profes- sionals显示文摘 | Ameen E C D M Guffey J J McMillan | 1996 | Journal of Business Ethics1996,15,5: | 1 |
| 12 | Relationship between chest compression rates and outcomes from cardiac arrest 显示文摘 | Idris AH Guffey D Aufderheide TP | 2012 | Circulation2012,125,24: | 1 |
| 13 | Relationship between chest\compression rates and outcomes from cardiac arrest显示文摘 | Idris AH Guffey D Aufderheide TP | 2012 | Circuiati on2012,125,24: | 1 |
| 14 | Relationship between chest compression rates and outcomes from cardiac arrest 显示文摘 | Idris AH Guffey D Aufderheide TP | 2012 | Circulation2012,125,24: | 1 |
| 15 | Thermal pretreatment of low-ranked coal for control of mercury emissions 显示文摘 | GUFFEY F D BLAND A E | 2004 | Fuel Process Teehnol2004,85,67: | 1 |
| 16 | Information Conveyed in Announcements of Analyst Coverage 显示文摘 | Branson B D Guffey D Pagach | 1998 | Contemporary Accounting Research1998,,15: | 1 |
| 17 | Pyrolysis of waste poly- styrene in heavy oil显示文摘 | Marsh JA Cha C Y Guffey F D | 1994 | Chem Eng Comm1994,129,: | 1 |
| 18 | Thermal pretreatment of low-ranked coal for control of mercury emissions显示文摘 | GUFFEY F D BLAND A E | 2004 | Fuel Process Technol2004,85,67: | 1 |
| 19 | Pyrolysis of waste polystyrene in heavy oil显示文摘 | Marsh J A Chat C Y Guffey F D | 1994 | Chemical Engineering Communi- cations1994,,129: | 1 |
| 20 | Thermal pretreatment of low-ranked coal for control of mercury emissions 显示文摘 | Guffey F D Bland A E | 2004 | Fuel Processing Technology2004,85,: | 1 |