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您的检索式：作者名="Guangjun Ge"
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| 1 | LDPC Coding Scheme for Improving the Reliability of Multi-Level-Cell NAND Flash Memory in Radiation Environments显示文摘Utilizing commercial off-the-shelf(COTS) components in satellites has received much attention due to the low cost. However, commercial memories suffer severe reliability problems in radiation environments. This paper studies the low-density parity-check(LDPC) coding scheme for improving the reliability of multi-level-cell(MLC) NAND Flash memory in radiation environments. Firstly, based on existing physical experiment works, we introduce a new error model for heavyion irradiations; secondly, we explore the optimization of writing voltage allocation to maximize the capacity of the storage channel; thirdly, we design the degree distribution of LDPC codes that is specially suitable for the proposed model; finally, we propose a joint detection-decoding scheme based on LDPC codes, which estimates the storage channel state and executes an adaptive log-likelihood ratio(LLR) calculation to achieve better performance. Simulation results show that, compared with the conventional LDPC coding scheme, the proposed scheme may almost double the lifetime of the MLC NAND Flash memory in radiation environments. | Guangjun Ge Liuguo Yin | 2017 | China Communications2017，14，8： | 1 |
| 2 | The“1+1”Therapy for Drug Addicts显示文摘The“1+1”TherapyforDrugAddicts￥GEGUANGJUNNarcoticsareamajorhazardaroundtheworld,oneoftheleadingkillersofpeople,togetherwithAID... | GE GUANGJUN | 1996 | China Today1996，45，12： | 0 |
| 3 | Immunogenic cell death effects induced by doxorubicin improved chemo-immunotherapy via restoration of granzyme B activity显示文摘Chemotherapy remains one of the irreplaceable treatments for cancer therapy.The use of immunogenic cell death(ICD)-inducing chemotherapeutic drugs offers a practical strategy for killing cancer cells,simultaneously eliciting an antitumor immune response by promoting the recruitment of cytotoxic immune cells and production of granzyme B(GrB).However,numerous malignant cancers adaptively acquired the capacity of secreting serpinb9(Sb9),a physiological inhibitor of GrB,which can reversibly inhibit the biological activity of GrB.To circumvent this dilemma,in this study,an integrated tailor-made nanomedicine composed of tumor-targeting peptide(Arg-Gly-Asp,RGD)decorated liposome,doxorubicin(DOX,an effective ICD inducer),and the compound 3034(an inhibitor of Sb9),is developed(termed as D3RL)for breast cancer chemo-immunotherapy.In vitro and in vivo studies show that D3RL can directly kill tumor cells and trigger the host immune response by inducing ICD.Meanwhile,D3RL can competitively relieve the inhibition of Sb9 to GrB.The restored GrB can not only effectively induce tumor immunotherapy,but also degrade matrix components in the tumor microenvironment,consequently improving the infiltration of immune cells and the penetration of nanomedicines,which in return enhance the combined antitumor effect.Taken together,this work develops an integrated therapeutic solution for targeted production and restoration of GrB to achieve a combined chemo-immunotherapy for breast cancer. | Tao Huang Xiaofan Sun Yingqiu Qi Xi Yang Linyao Fan Mengdie Chen Yale Yue Hong Ge Yiye Li Guangjun Nie Huan Min Xianfu Sun | 2023 | Nano Research2023，16，12： | 0 |
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