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| 1 | GENETIC DIVERSITY AMONG CHINESE SIKA DEER (CERVUS NIPPON) POPULATIONS AND RELATIONSHIPS BETWEEN CHINESE AND JAPANESE SIKA DEER显示文摘Sika deer (Cervus nippon) is a cervid endemic to mainland and insular Asia and endan-gered. We analyzed variation in the mitochondrial DNA (mtDNA) control region for four subspecies to understand the genetic diversity, population structure and evolutionary history in China. 335 bp were se-quenced and eight haplotypes were identified based on 25 variable sites among the populations. Sika deer in China showed lower genetic diversity, sug-gesting a small effective population size due to habi-tat fragmentation, a low number of founder individu-als, or the narrow breeding program. AMOVA analy-sis indicated that there was significant genetic subdi-vision among the four populations, but no correlation between the genetic and geographic distance. Phy-logenetic analyses also revealed that Chinese sika deer may be divided into three genetic clades, but the genetic structure among Chinese populations was inconsistent with subspecies designations and pre-sent geographic distribution. Including the sequence data of Japanese sika deer, the results indicated that Chinese populations were more closely related to Southern Japanese populations than to the Northern Japanese one, and the Taiwan population was closer to populations of Northeastern China and Sichuan than to those of Southern China. | Lü Xiaoping WEI Fuwen LIMing YANG Guang LIU Hai | 2006 | Chinese Science Bulletin2006，51，4： | 7 |
| 2 | Chinese medicine formulas for nonalcoholic fatty liver disease: Overview of systematic reviews显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)affects more than one-quarter of the global population.Due to the lack of approved chemical agents,many patients seek treatment from traditional Chinese medicine(TCM)formulas.A variety of systematic reviews have been published regarding the effectiveness and safety of TCM formulas for NAFLD.AIM To critically appraise available systematic reviews and sort out the high-quality evidence on TCM formulas for the management of NAFLD.METHODS Seven databases were systematically searched from their inception to 28 February 2020.The search terms included“non-alcoholic fatty liver disease,”“Chinese medicines,”“systematic review,”and their synonyms.Systematic reviews involving TCM formulas alone or in combination with conventional medications were included.The methodological quality and risk of bias of eligible systematic reviews were evaluated by using A Measure Tool to Assess Systematic Reviews 2(AMSTAR 2)and Risk of Bias in Systematic Review(ROBIS).The quality of outcomes was assessed by the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system.RESULTS Seven systematic reviews were ultimately included.All systematic reviews were conducted based on randomized controlled trials and published in the last decade.According to the AMSTAR 2 tool,one systematic review was judged as having a moderate confidence level,whereas the other studies were rated as having a low or extremely low level of confidence.The ROBIS tool showed that the included systematic reviews all had a high risk of bias due to insufficient consideration of identified concerns.According to the GRADE system,only two outcomes were determined as high quality;namely,TCM formulas with the HuoXueHuaYu principle were better than conventional medications in ultrasound improvement,and TCM formulas were superior to antioxidants in alanine aminotransferase normalization.Other outcomes were downgraded to lower levels,mainly because of heterogeneity among studies,not meeting optimal information sample size,and inclusion of excessive numbers of small sample studies.Nevertheless,the evidence quality of extracted outcomes should be further downgraded when applying to clinical practice due to indirectness.CONCLUSION The quality of available systematic reviews was not satisfactory.Researchers should avoid repeatedly conducting systematic reviews in this area and focus on designing rigorous randomized controlled trials to support TCM formula applications. | Liang Dai Wen-Jun Zhou Linda L D Zhong Xu-Dong Tang Guang Ji | 2021 | World Journal of Clinical Cases2021，9，1： | 3 |
| 3 | QTL effects and epistatic interaction for flowering time and branch number in a soybean mapping population of Japanese×Chinese cultivars显示文摘Flowering time and branching type are important agronomic traits related to the adaptability and yield of soybean. Molecular bases for major flowering time or maturity loci, E1 to E4, have been identified. However, more flowering time genes in cultivars with different genetic backgrounds are needed to be mapped and cloned for a better understanding of flowering time regulation in soybean. In this study, we developed a population of Japanese cultivar(Toyomusume)×Chinese cultivar(Suinong 10) to map novel quantitative trait locus(QTL) for flowering time and branch number. A genetic linkage map of a F_2 population was constructed using 1 306 polymorphic single nucleotide polymorphism(SNP) markers using Illumina Soy SNP8 ki Select Bead Chip containing 7 189(SNPs). Two major QTLs at E1 and E9, and two minor QTLs at a novel locus, qFT2_1 and at E3 region were mapped. Using other sets of F_2 populations and their derived progenies, the existence of a novel QTL of qFT2_1 was verified. qBR6_1, the major QTL for branch number was mapped to the proximate to the E1 gene, inferring that E1 gene or neighboring genetic factor is significantly contributing to the branch number. | YANG Guang ZHAI Hong WU Hong-yan ZHANG Xing-zheng LüShi-xiang WANG Ya-ying LI Yu-qiu HU Bo WANG Lu WEN Zi-xiang WANG De-chun WANG Shao-dong Kyuya Harada XIA Zheng-jun XIE Fu-ti | 2017 | Journal of Integrative Agriculture2017，16，9： | 3 |
| 4 | A 3D Geological Model Constrained by Gravity and Magnetic Inversion and its Exploration Implications for the World-class Zhuxi Tungsten Deposit, South China显示文摘The Zhuxi tungsten deposit in Jiangxi Province,South China,contains a total W reserve of about 2.86 Mt at an average grade of 0.54 wt%WO3,representing the largest W deposit in the world.Numerous studies on the metallogeny of the deposit have included its timing,the ore-controlling structures and sedimentary host rocks and their implications for mineral exploration.However,the deep nappe structural style of Taqian-Fuchun metallogenic belt that hosts the W deposit,and the spatial shape and scale of deeply concealed intrusions and their sedimentary host rocks are still poorly defined,which seriously restricts the discovery of new deposits at depth and in surrounding areas of the W deposit.Modern 3 D geological modeling is an important tool for the exploration of concealed orebodies,especially in brownfield environments.There are obvious density contrast and weak magnetic contrast in the ore-controlling strata and granite at the periphery of the deposit,which lays a physical foundation for solving the 3 D spatial problems of the ore-controlling geological body in the deep part of the study area through gravity and magnetic modeling.Gravity data(1:50000)and aeromagnetic data(1:50000)from the latest geophysical surveys of 2016-2018 have been used,firstly,to carry out a potential field separation to obtain residual anomalies for gravity and magnetic interactive inversion.Then,on the basis of the analysis of the relationship between physical properties and lithology,under the constraints of surface geology and borehole data,human-computer interactive gravity and magnetic inversion for 18 cross-sections were completed.Finally,the 3 D geological model of the Zhuxi tungsten deposit and its periphery have been established through these 18 sections,and the spatial shape of the intrusions and strata with a depth of 5 km underground were obtained,initially realizing―transparency‖for ore-controlling bodies.According the analysis of the geophysical,geochemical,and geological characteristics of the Zhuxi tungsten deposit,we discern three principles for prospecting and prediction in the research area,and propose five new exploration targets in its periphery. | YAN Jiayong LÜ Qingtian QI Guang FU Guangming ZHANG Kun LAN Xueyi GUO Xin WEI Jin LUO Fan WANG Hao WANG Xu | 2020 | Acta Geologica Sinica(English Edition)2020，94，6： | 3 |
| 5 | Composi tion and preservation of the Cheng jiang fauna-lower Cambrian soft-bodied biota显示文摘 | Hou Xian guang Ramskold L Bergstrom J | 1991 | Zoologica Scripta1991，20，： | 1 |
| 6 | Synthesis,characterization and biological activity of lanthanum(Ⅲ) complexes containing 2-methylene-1,10-phenanthroline units bridged by aliphatic diamines显示文摘 | FENG H L HAl L | 2006 | Journal of Inorganic Biochemistry2006，100，： | 1 |
| 7 | Effect of aluminum and calcium on growth of wheat seedlings and germination of seeds 显示文摘 | Shen Z G Wang J L Guang H Y | 1993 | J Plant Nutr1993，16，： | 1 |
| 8 | An exploratory study of the corrosion of Mg al- loys during interrupted salt spray testing 显示文摘 | Ming C Patrik S Samuel Br Ming L Guang L An- drej A | 2009 | Corrosion Science2009，51，6： | 1 |
| 9 | A meshless local point collocation method for free vibration analysis of laminated composite plates显示文摘 | Song X Guang C L Wei H | 2011 | Composite Structures2011，93，2： | 1 |
| 10 | A comparative dosimetric study for treating left-sided breast cancer for small breast size using five different radiotherapy techniques: convention nal tangential filed- in-filed, tangential-lMRT, multi-beam IMRT and VMAT显示文摘 | GUANG H JIN L X CHEN X W | 2013 | Radiol Oncol2013，4，8： | 1 |
| 11 | Reconstruction Plates to bridge mandibular defect s:a clinicai and experimental investigation in biomechanical a speets 显示文摘 | Yi Z Jian G Guang Y Ling L Fu Y Guo C | 1999 | Int J Oral Maxi I 10fac Surg1999，28，6： | 1 |
| 12 | Role of epidermal growth factor receptor over expression, K-ras point mutation and ernyc amplification in the carcinogenesis of non-small cell lung cancer 显示文摘 | SEKINE L TAKAMI S GUANG S G | 1998 | Oncol Rep1998，5，2： | 1 |
| 13 | Synthesis and characterization of poly-α,β--g-poly(glycolide)amphiphilic graft copolymers as potential drug carriers显示文摘 | Tao P Jing S Guang L | 2006 | Colloid Polym Sci2006，284，83： | 1 |
| 14 | Role of epidermal growth factor receptor overexpression, K-ras point mutation and c-myc amplification in the carcinogenesis of non-small cell lung cancer 显示文摘 | Sekine L Takami S Guang SG | 1998 | Oncol Rep1998，5，2： | 1 |
| 15 | Enema reduction of intussusception by hydrostatic pressure under ultrasound guidance: a report of 377 cases显示文摘 | Guang da W Shoujun L | 1988 | J Pediatr Surg1988，23，9： | 1 |
| 16 | Artificial neural network power system stabilizer trained with an improved BP algorithm显示文摘 | Guang L Cheng S Zhou R | 1996 | IEE Proceedings1996，143，2： | 1 |
| 17 | Vitamin A deficiency and child feeding in Beijing and Guizhou,China显示文摘 | JING X J LIANG M L GUANG L L | 2008 | J World Pediatr2008，4，1： | 1 |
| 18 | Highly uniform Gd203 hollow microspheres: template -directed synthe- sis and luminescence properties 显示文摘 | Guang J Hong P Y Kai L | 2010 | Langmuir2010，26，7： | 1 |
| 19 | Facile synthesis and lu- minescence properties of highly uniform MF/YV04 : Ln3+ ( Ln = Eu, Dy, and Sin) composite microspheres 显示文摘 | Guang J Kai L Yu H Z | 2009 | Crystal Growth & Design2009，9，： | 1 |
| 20 | Dimerization,DNA binding and transactivation properties of hypoxia-induced factor 1 显示文摘 | Jiang BH Elizabeth Rue Guang L | 1996 | J Biol Chem1996，271，17： | 1 |
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