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| 1 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 2 | Association of nonalcoholic fatty liver disease with type 2 diabetes: clinical features and independent risk factors in diabetic fatty liver patients显示文摘Nonalcoholic fatty liver disease(NAFLD) is a common chronic liver disease in China, of which diabetic fatty liver (DFL) accounts for a large proportion in clinic. DFL is a disease without specific clinical features and lacking of confirmatory laboratory tests, and the etiology of hepatic steatosis remains poorly understood. The aim of this paper was to explore the clinical characteristics and to determine associated risk factors in type 2 diabetes patients with fatty liver. METHODS: A total of 166 patients, 53 in DFL group and 113 in NDFL(diabetes without fatty liver) group participated in this study. Serum fasting blood glucose (FBG), alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphate (AKP), gamma glutamyl transpeptidase (GGT), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) were measured in both groups. And these variables were analyzed by using Student’ s t test and logistic regression model. RESULTS:A progressive increase in the level of FBG, ALT, AST, AKP, GGT, TG( P<0.05) and a decrease of HDL-C(P<0.01)were observed from DFL group to NDFL group. And there was no statistical difference in the level of TC between the two groups. CONCLUSIONS:Dyslipidemia, dysglycemia and elevation of liver enzyme can be seen more frequently in the DFL patients than in the NDFL patients. The successive escalation of serum ALT and TG levels and the lower HDL-C level are the independent risk factors of DFL. | Department of Digestive Medicine, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Jin HB, Gu ZY, Yu CH and Li YM) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 3 | 环境铅暴露与血压的关系:2003-2010美国健康和营养调查显示文摘在铅暴露逐渐降低的环境下,该文通过分析2003-2010美国健康和营养调查资料,旨在研究血铅与血压、高血压的关系。纳入研究对象12 725人,其中非洲裔21.1%,西语裔20.5%,白人58.4%,女性48.7%。与非非洲裔比较,非洲裔的血压[126.5/71.9比123.9/69.6mm Hg(1mm Hg=0. | Hara A Thijs L Asayama K Gu YM Jacobs L Zhang ZY Liu YP Nawrot TS Staessen JA 刘莉 叶鹏 | 2014 | 中华高血压杂志2014，22，10： | 3 |
| 4 | NGF promotes collateral sprouting of cholinergic fibers in the septo-hippocampal cholinegic system of aged rats with fimbria transection显示文摘 | He YS Yao ZB Gu YM | 1992 | Brain Res1992，586，： | 2 |
| 5 | NGF promotes collateral prouting of cholinergic fibers in the septohippocampal cholinergic system of aged rats with fimbria transection 显示文摘 | HE YS Yao ZB Gu YM | 1992 | Brain Res1992，586，： | 1 |
| 6 | Transcathter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model显示文摘 | Gu X Han YM Titus JL | 2000 | Catheter Cardiovasc Interv2000，50，2： | 1 |
| 7 | Transcatheter closure ofmembranous ventricular septal defects with a new nitinol prosthesis in a natural swine model显示文摘 | Gu XP Han YM Titus TL | 2000 | Catheter Cardiovasc Interv2000，50，4： | 1 |
| 8 | Fabrication and properties of a porous chitin/chitosan conduit for nerve regeneration显示文摘 | Yang YM Gu XS Tan RX | 2004 | Biotechnol Lett2004，26，23： | 1 |
| 9 | Transeatheter closure of membranous ventricular septal defects with a nitinol prosthesis in a natural swine model 显示文摘 | Gu X Han YM Titus JL | 2000 | Cather Cardiovasc Intervent2000，50，2： | 1 |
| 10 | Injury potential to venous valves from Amplatz thrombectomy device 显示文摘 | Sharafuddin MJ Gu X Han YM | 1999 | J Vasc Intervent Radiol1999，10，1： | 1 |
| 11 | Nerve growth factor promotes collateral sprouting of cholinergic filbers in the septohippocampal cholinergic system of aged rats with fimbria transaction 显示文摘 | He YS Yao ZB Gu YM | 1992 | Brain Res1992，586，1： | 1 |
| 12 | The controlling biodeg-radation of chitosan fibers by N-acetylation in vitro and in vivo显示文摘 | Yang YM Hu W Wang XD Gu XS | 2007 | J Mater Sci Mater Med2007，18，11： | 1 |
| 13 | Injury potential to venous valves from the Amplatz thrombectomy device 显示文摘 | Sharafuddin MA Gu X Han YM | 1999 | J Vasc Interv Radiol1999，10，1： | 1 |
| 14 | Transcatheter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model 显示文摘 | Gu XP Han YM Titws X | 2000 | Cathet Cardiovasc Intervnet2000，50，： | 1 |
| 15 | Transcatheter closure of atrial septal defect oceluder显示文摘 | Han YM Titus JL | 1999 | Catheter Cardiovase Interv1999，50，： | 1 |
| 16 | Transcatheter closure of membranous ventricular septal defects with a nitinol prosthesis in a natural swine model 显示文摘 | Gu X Han YM Titus JL | 2000 | Cathet Cardiovasc Intervent2000，50，2： | 1 |
| 17 | NGF promotes collateral sproutingof cholinergic fibers in the septo-hippocampal cholinegic systemof aged rats with fimbria transection 显示文摘 | He YS Yao ZB Gu YM | 1992 | Brain Res1992，586，： | 1 |
| 18 | Therapeutic efficacy observation on acupuncture plus medication for rheumatoid arthritis显示文摘 | Liang YY Guo YM Gu JQ | 2012 | J Acupunct Tuina Sci2012，10，4： | 1 |
| 19 | Transcatheter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model显示文摘 | Gu X Han YM Titus JL | 2000 | Catheter Cardiovasc Interv2000，50，4： | 1 |
| 20 | Transcatheter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model显示文摘 | Gu XP Han YM Titus TL | 2000 | Catheter Cardiovasc Interv2000，50，4： | 1 |
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