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278篇 您的检索式:作者名="Granger P"
    题名 作者 年代 出处 被引量
1针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) 2020英国医学杂志中文版2020,23,9:5
2胎盘生长因子抑制胎盘缺血引起的高血压显示文摘先兆子痫最有效的治疗是提前分娩出胎儿和胎盘。胎盘缺血的发生对先兆子痫发病有至关重要的影响,因为在动物或人类,子宫灌注压减少(reduced uterine perfusion pressure,RUPP)可诱发胎盘缺血/缺氧,刺激机体释放高血压胎盘因子进入母体循环。抗血管生成因子可溶性fms样酪氨酸激酶1(soluble fms-like tyrosine kinase-1,sFlt-1)可拮抗和减少有生物活性的血管内皮生长因子( vascular endothelial growth factor, VEGF)和胎盘生长因子( placental growth factor, PIGF),研究发现在RUPP大鼠和先兆子痫患者中,sFlt-1水平升高。刘莉 叶鹏 Spradley FT Tan AY Joo WS Daniels G Kussie P Karumanchi SA Granger JP 2016中华高血压杂志2016,24,2:2
3An emerging role for inflammatory cytokines in hypertension 显示文摘GRANGER J P 2006Am J Physiol Heart Circ Physiol2006,290,:1
4Cosmogenic nuclide burial ages and provenance of the Xigeda paleo-lake: Implicatiom for evolution of the Middle Yangtze River 显示文摘Kong P Granger D E Wu F Y 2009Earth and Planetary Science Letters2009,278,:1
5Patho- physiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction 显示文摘Granger J P AlexanderB T LlinasM T 2001Hypertension2001,38,3:1
6The role of reactive oxygen metabolites in platelet activating factor induced increases in intestinal microvasculature and mucosal permeability 显示文摘Kubes P Granger D N 1990Gastroenterol- ogy1990,98,:1
7Yeast wall protein 1 of Candida albicans 显示文摘Granger B L Flenniken M L Davis D A Mitchell A P Cutler JE 2005Microbiology2005,151,:1
8Cosmogenic nuclide burial ages and provenance of the Xigeda paleo-lake: Implications for evolution of the Middle Yangtze River显示文摘Kong P Granger D E Wu F Y Caffee M W Wang Y ] Zhao X T Zheng Y 2009Earth and Planetary Science Letters2009,278,:1
9The acute respiratory management of cervical spinal cord injury in the first 6 weeks after injury : a systematic review 显示文摘BERNEY S BRAGGE P GRANGER C 2011Spinal Cord2011,49,1:1
10A systematic review and me-ta-analysis of clinicopathologic factors linked to intravesical recur-rence after radical nephroureterectomy to treat upper tract urothelialcarcinoma 显示文摘Seisen T Granger B Colin P 2015Eur Urol2015,67,6:1
11Impact of hospitalization for acute coronary events on subsequent mortality in patients with chronic heart failure显示文摘Abrahamsson P Dobson J Granger CB 2009Eur Heart J2009,30,3:1
12Forecasting transformed series显示文摘Granger CW Newbold P 1976Journal of Royal Statistical Society Series B1976,30,:1
13Fluorine containing beta-cyclodextrin:a new class of amphiphilic carriers显示文摘Granger C E Felix C P Parrot-Lopez H P 2000Tetrahedron Letters2000,41,48:1
14Direct quantification of protein partitioning in oil-in-water emulsion by front-face fluorescence:Avoiding the need for centrifugation显示文摘GRANGER C BAREY P TOUTAIN J 2005Colloids and Surfaces B:Biointerfaces2005,43,:1
15The role of reactive oxygen metabolites in platelet activating factor-induced increases in intestinal microvasculature and mucosal permeability显示文摘Kubes P Granger DN 1990Gastroenterology1990,98,:1
16Accelerator mass spectrometry in geologic research 显示文摘Muzikar P Elmore D Granger D E 2003GSA Bulletin2003,115,6:1
17Surface recon- struction of supported Pd on LaCoO3 : consequences on the catalytic properties in the decomposition of N2O 显示文摘Dacquin J P Dujardin C Granger P 2008J Catal2008,253,1:1
18Spurious Regressions in Economet- rics显示文摘Granger C W J P Newbold 1974Journal of Econometrics1974,12,:1
19Nitric oxide:an endogenous modulator of leukocyteadhesion显示文摘Kubes P Suzuki M Granger DN 1991Prec Natl Acad Sci USA1991,88,11:1
20A systematic review and Meta-analysis of clinicopathologic factors linked to in- travesical recurrence after radical nephroureterectomy to treat upper tract urothelial carcinoma显示文摘Seisen T Granger B Colin P 2014Eur Urol2014,,01:1
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