|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Micro RNA expression in hepatitis C virus-related malignancies: A brief review显示文摘Not only is chronic hepatitis C virus(HCV) infection a major public health problem,but also it can cause hepatocellular carcinoma and,more rarely,nonHodgkin's lymphoma.These characteristics mean that HCV is the only virus infecting humans that is able to cause two different cancers.The fine pathogenetic and molecular mechanisms by which HCV induces these two malignancies are not completely clear.In the last decade,it has been shown that microRNAs(miRNAs),a class of 21-23-nucleotide molecules modulating posttranscriptional gene expression,make an important contribution to the pathogenesis of several cancers and are also considered highly promising biomarkers.Here,we briefly describe the current knowledge about microRNAs' involvement in HCV-related molecular oncogenesis.We decided to focus our attention on studies fully conducted on ex vivo samples with this specific etiology,and on cultured cell lines partially or completely expressing the HCV genome.Some of the results reported in this review are controversial,possibly because of methodological issues,differences in sampling size and features,and ethnicity of patients.What is certain is that miRNAs play a remarkable role in regulating gene expression during oncogenetic processes and in viral infection.A clear understanding of their effects is fundamental to elucidating the mechanisms underlying virus-induced malignancies. | Laura Gragnani Alessia Piluso Elisa Fognani Anna Linda Zignego | 2015 | World Journal of Gastroenterology2015，21，28： | 2 |
| 2 | Extrahepatic manifestations of chronic hepatitis C virus infection显示文摘 | Patrice Cacoub Laura Gragnani Cloe Comarmond Anna Linda Zignego | 2014 | Digestive and Liver Disease2014，，： | 2 |
| 3 | Is there an ideal animal model to study hypertrophic scarring? 显示文摘 | RAMOS M L GRAGNANI A FERRE | 2008 | J Burn Care Res2008，29，2： | 1 |
| 4 | Sensory involvement in spinal-bulbar muscular atrophy (Kennedy's disease) 显示文摘 | Antonini G Gragnani F Romaniello A | 2000 | Muscle Nerve2000，23，： | 1 |
| 5 | Myasthenia gravis in the elderly 显示文摘 | Antonini G Morino S Gragnani F | 1996 | Acta Neurol Stand1996，93，： | 1 |
| 6 | On thedominance of filamentous cyanobacteria in shallow,turbid lakes 显示文摘 | Scheffer M Rinaldi S Gragnani A | 1997 | Ecology1997，78，1： | 1 |
| 7 | Resid hydrocracker produces low-sulfur diesel from difficult feeds显示文摘 | S Putek A Gragnani | 2006 | Hydrcarbon Processing May2006，85，5： | 1 |
| 8 | Topical tamoxifen therapy in hypertrophic scars or keloids in burns 显示文摘 | Gragnani A Warde M Furtado F | 2010 | Arch Dermatol Res2010，302，1： | 1 |
| 9 | Thermolysin in human cul-tured keratinocyte isolation显示文摘 | Gragnani A Sobral CS Ferreira LM | | 0，，01： | 1 |
| 10 | The hepatitis C virus infection as a systemic disease显示文摘 | Anna Linda Zignego Laura Gragnani Carlo Giannini Giacomo Laffi | 2012 | Internal and Emergency Medicine2012，，3： | 1 |
| 11 | Myasthenia gravis in the elderly显示文摘 | Antonini G Morino S Gragnani F | 1996 | Acta Neurol Scand1996，93，： | 1 |
| 12 | Myasthenia gravis in the elderly:a hospital based study显示文摘 | Antonini G Morino S Gragnani F | 1996 | Acta Neurol Scand1996，93，4： | 1 |
| 13 | Obsessions andcompulsions : normative data on the Padua Inventory from an Italiannon - clinical adolescent sample 显示文摘 | Mancini F Gragnani A Orazi F Pietrangeli M G | 1999 | Behaviour Research and Thera-py1999，37，： | 1 |
| 14 | Sensory involvement in spinal-bulbar muscular atrophy (Kennedy's disease) 显示文摘 | Antonini G Gragnani F Romaniello A etal | 2000 | Muscle Nerve2000，23，2： | 1 |
| 15 | Pollution control policies and natural resource dynamics 显示文摘 | Rinaldi S Sanderson W Gragnani A | 1996 | Journal of Environmental Management1996，48，4： | 1 |
| 16 | Experimental model for fibroblast culture 显示文摘 | Keira S M Ferreira L M Gragnani A | 2004 | Acta Cir Bras2004，19，： | 1 |
| 17 | The effect of increasing fluence on the treatment of actinic keratosis and photodamage by photodynamic therapy with 5-aminolevulinic acid and intense pulsed light显示文摘 | Haddad A Santos ID Gragnani A | 2011 | Photomed Laser Surg2011，29，6： | 1 |
| 18 | EU Regulation 1151/2012 on Quality Schemes for Agricultural Products and Foodstuffs 显示文摘 | Gragnani M | 2013 | European Food & Feed Law Review2013，8，6： | 1 |
| 19 | On the dominance of filamentous cyanobacteria in shallow, turbid lakes显示文摘 | Scheffer M Rinaldi S Gragnani A | 1997 | Eco|ogy1997，78，1： | 1 |
| 20 | Sensory involvement in spinal -bulbar muscular atrophy( Kennedy's disease) 显示文摘 | Antonlni G Gragnani F Romaniello A | 2000 | Mus- cle Nerve2000，23，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员