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| 1 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 2 | A study on the friction and wear characteristics of brake pads for Al MMC brake disc 显示文摘 | Kwon S J Goo B C | 2000 | KeyEng Mat2000，183，1： | 2 |
| 3 | A study on the friction and wear characteristics of brake pads for Al MMC brake disc显示文摘 | Goo B C | 2000 | Key Eng Mat2000，183，1： | 1 |
| 4 | Response of spring wheat to nitrogen fertilizers of different nitrification rates显示文摘 | Goos R J Schimelfenig J A Bock B R | 1999 | Agronomy Journal1999，91，2： | 1 |
| 5 | The formation and growth of bulblets from bulblet sections with swollen basal plate in Lilium oriental hybrid ‘Casa Blanca' 显示文摘 | HAN B H YAE B W GOO D H | 1999 | J Korean Soc Hort Sci1999，40，6： | 1 |
| 6 | Atypical pulmonary metastases:spectrum of radioIogic findings显示文摘 | Seo J B Im J G Goo J M | 2001 | Radiographics2001，21，2： | 1 |
| 7 | Treatment of enlarged pores with the quasi long-pulsed versus Q-switched 1 064 run Nd : YAG lasers: A split-face, comparative, controlled study 显示文摘 | Roh M Goo B Jung J | 2011 | Laser Ther2011，20，： | 1 |
| 8 | A study on the effect of weld- ing residual stress and weld bead profiles on fatigue behavior显示文摘 | Goo B C Kim J Seo J W | 2004 | Key Engineering Materials2004，，： | 1 |
| 9 | Transcatheter arterial embolization of pulmonary sequestration in neonates:long-term followup results显示文摘 | Lee K H Sung K B Yoon H K Ko G Y Yoon C H Goo H W | | 0，，： | 1 |
| 10 | Effects of growth regulators and light on the formation and proliferation of bulblets with swollen basal plate from in vitro culture of bulbscales in Lilium oriental hybrid 'Casa Blanca'显示文摘 | HAN B H YAE B W GOO D H | 1999 | J Korean Soc Hort Sci1999，40，4： | 1 |
| 11 | Design and Experiment of a3DOF Parallel Micro-Mechanism Utilizing Flexure Hinges显示文摘 | Byung JY Heung YN Goo B C etc | 2002 | IEEE International conference on Robotics and Automation2002，，： | 1 |
| 12 | Development of limitload solutions for corroded gas pipelines 显示文摘 | CHOI J B GOO B K KIM J C | 2003 | InternationalJournal of Pressure Vessels and Piping2003，80，： | 1 |
| 13 | Compressibility effect on the gas flow and heat transfer in a microtube 显示文摘 | Goo Z Y Wu X B | 1997 | International Journal of Heat Mass Transfer1997，40，13： | 1 |
| 14 | Re-emergence of potato and tomato late blight in the United States 显示文摘 | FRY W E GOO DWIN S B | 1997 | Plant Disease1997，81，12： | 1 |
| 15 | Development of compacted vermicular graphite cast iron for railway brake discs 显示文摘 | Lim C H Goo B C | 2011 | Metals and Materials International2011，17，2： | 1 |
| 16 | Evaluation of impact dam- age and residual compression strength after impact of glass/epoxy laminate composites for lightweight bogie frame induced by ballast -flying phenomena 显示文摘 | Goo J S Shin K B Kim J S | 2012 | Jour- nal of the Korean Society for Railway2012，15，2： | 1 |
| 17 | Development of limit load solutions for corroded gas pipelines显示文摘 | CHOI J B GOO B K KIM J C | 2003 | International Journal of Pressure Vessels and Piping2003，80，： | 1 |
| 18 | Development of limit load solutions for corroded gas pipelines 显示文摘 | J B Choi B K Goo J C Kim | 2003 | International Journal of Pressure Vessels and Piping2003，80，： | 1 |
| 19 | Immunotherapy of malignant melanoma with tumor lysate-pulsed autologous monocyte-derived dendritic cells 显示文摘 | Kim DS Kim DH Goo B | 2011 | Yonsei Med J2011，52，6： | 1 |
| 20 | Effect of ammonium thiosulfate and dicyandiamide on residual ammonium in fertilizer bands显示文摘 | Goos R J Johnson B E | 1992 | Communications in Soil Acience and Plant Analysis1992，23，： | 1 |
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