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| 1 | Interferon-Gamma Release Assay is Not Appropriate for the Diagnosis of Active Tuberculosis in High-Burden Tuberculosis Settings: A Retrospective Multicenter Investigation显示文摘 | Wan-Li Kang Gui-Rong Wang Mei-Ying Wu Kun-Yun Yang Er-Tai A Shu-Cai Wu Shu-Jun Geng Zhi-Hui Li Ming-Wu Li Liang Li Shen-Jie Tang | 2018 | Chinese Medical Journal2018，，3： | 30 |
| 2 | Pharmacokinetics of the prototype and hydrolyzed carboxylic forms of ginkgolides A, B, and K administered as a ginkgo diterpene lactones meglumine injection in beagle dogs显示文摘Ginkgo diterpene lactones meglumine injection(GDLI)is a commercially available product used for neuroprotection.However,the pharmacokinetic properties of the prototypes and hydrolyzed carboxylic forms of the primary components in GDLI,i.e.,ginkgolide A(GA),ginkgolide B(GB),and ginkgolide K(GK),have never been fully evaluated in beagle dogs.In this work,a simple,sensitive,and reliable method based on ultra-fast liquid chromatography-tandem mass spectrometry(UFLC-MS/MS)was developed,and the prototypes and total amounts of GA,GB,and GK were determined in beagle dog plasma.The plasma concentrations of the hydrolyzed carboxylic forms were calculated by subtracting the prototype concentrations from the total lactone concentrations.For the first time,the pharmacokinetics of GA,GB,and GK were fully assessed in three forms,i.e.,the prototypes,the hydrolyzed carboxylic forms,and the total amounts,after intravenous administration of GDLI in beagle dogs.It was shown that ginkgolides primarily existed in the hydrolyzed form in plasma,and the ratio of hydrolysates to prototype forms of GA and GB decreased gradually to a homeostatic ratio.All of the three forms of the three ginkgolides showed linear exposure of AUC to the dosages.GA,GB,and GK showed a constant half-life approximately 2.7,3.4,and 1.2 h,respectively,which were consistent for the forms at three dose levels(0.3,1.0,and 3.0 mg·kg^(-1))and after a consecutive injection of GDLI for 7 days(1.0 mg·kg^(-1)). | WANG Shu-Yao A Ji-Ye FEI Fei GENG Jian-Liang PENG Ying OUYANG Bing-Chen WANG Pei JIN Xiao-Liang ZHAO Yu-Qing WANG Jian-Kun GENG Ting LI Yan-Jing HUA NG Wen-Zhe WANG Zhen-Zhong XIAO Wei WANG Guang-Ji | 2017 | Chinese Journal of Natural Medicines2017，15，10： | 9 |
| 3 | Reaction decoupling in thermochemical fuel conversion and technical progress based on decoupling using fluidized bed显示文摘Thermochemical conversion of fuels via pyrolysis/carbonization,cracking,gasification and combustion has to involve a number of individual reactions called attribution reactions to form an intercorrelated reaction network for any conversion process.By separating one or some attribution reactions from the others to decouple their interactions existing in the reaction network,the so-called reaction decoupling enables a better understanding of the complex thermal conversion process and further the optimization of the conditions for attribution reactions as well as the entire conversion process to realize advanced performances.The dual bed conversion and two-stage conversion are the two representative types of fuel conversion technologies developed in recent years based on reaction decoupling.Many technical advantages have been proven for such decoupling fuel conversion technologies,such as poly-generation of products,low-cost production of high-grade products,elimination of undesirable products or pollutants,easy operation and control,and so on.The treated fuels with decoupling conversion technologies mainly include solid biomass and coal,as well as liquid petroleum oil.This paper is devoted to reiteration of the reaction decoupling concept and further to reviewing the research,developments and successful applications of several decoupling fuel conversion technologies of two such types by using fluidized bed as their major reactors. | Zhennan Han Sulong Geng Xi Zeng Shipei Xu a Ping An Jiguang Cheng Jun Yang Feng Li Suyi Zhang Miao Liu Guoqing Guan Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，2： | 8 |
| 4 | 血清netrin-1增加与缺血性脑卒中预后改善相关显示文摘先前的实验研究表明,血清netrin-1与缺血性脑卒中进展相关。进一步了解缺血性脑卒中患者中netrin-1的变化可能为缺血性脑卒中的预后评估提供新的思路。该研究旨在探讨血清netrin-1与缺血性脑卒中预后的关系。研究人员测定3346例中国急性缺血性脑卒中抗高血压试验(China antihypertensive trial in acute ischemic stroke,CATIS)中缺血性脑卒中患者基线血清netrin-1水平,所有患者均在脑卒中发病后3个月进行随访。主要观察指标是脑卒中发病后3个月内死亡和严重残疾(改良Rankin 量表评分≥3)。 | 刘莉 叶鹏 Guo D Zhu Z Zhong C Peng H Wang A Xu T Peng Y Xu T Chen CS Li Q Ju Z Geng D Chen J Zhang Y He J | 2019 | 中华高血压杂志2019，27，5： | 6 |
| 5 | Fast multipole method for scattering from an arbitrary PEC target above or buried in a lossy halfspace 显示文摘 | A Sullivan and L Carin | 2001 | IEEE Trans AP2001，49，5： | 1 |
| 6 | Precise muhibeam acoustic ba- thymetry显示文摘 | GENG Xueyi ZIELINSKI A | 1999 | Marine Geodesy1999，，22： | 1 |
| 7 | An improved method to knock out the asd gene of Salmonella enterica serovar Pul- lorum显示文摘 | GENG S Z JIAO X A PAN Z M | 2009 | J Biomed Biotechnol2009，2009，： | 1 |
| 8 | UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic acidanalogues from Artemisia capillaris as a traditional Chinese herb for the treatment of hepatitis显示文摘 | Zhao Y Geng C A Ma Y B | 2014 | Journal of Ethnopharmaeolo gy2014，156，28： | 1 |
| 9 | Expression and characterization of a novel metagenome-derived cellulase Exo2band its application to improve cellulase activity in Trichoderma reesei显示文摘 | Geng A L Zou G Yan X | 2012 | Appl Microbiol Biotechnol2012，96，4： | 1 |
| 10 | Rapid improvement in cortical neuronal integrity in amyotrophic lateral sclerosis detected by proton magnetic resonance spectroscopic imaging显示文摘 | Kalra S Tai P Genge A | 2006 | J Neurol2006，253，8： | 1 |
| 11 | A comparison of the proximal femoral nail antirotation device and dynamic hip screw in the treatment of unstable pertrochanteric fracture显示文摘 | Xu YZ Geng DC Mao HQ et a/ | 2010 | J Int Med Res2010，38，4： | 1 |
| 12 | Durham adaptive optics real-time controller显示文摘 | Basden A Geng D Myers R | 2010 | Applied Optics2010，49，32： | 1 |
| 13 | Time - domain Simulation and Nonlinear Analysis on Ride Performance of Four - wheel Vehicles显示文摘 | Wang Y S He H Geng A L | 2008 | Journal of Physics:2008，96，： | 1 |
| 14 | Effects of dietary L-cami- tine and coenzyme Q10 supplementation on performance and ascites mortality of broilers显示文摘 | Geng A L Guo Y M Yuan J M | 2004 | Archives of Animal Nu- trition2004，58，： | 1 |
| 15 | The effects of ox-l,DL in hu- man atherosclerosis may be mediated in part via the toll-like re- ceptor 4 pathway显示文摘 | Geng H Wang A Rong G | 2010 | Mo| Cell Biochem2010，342，12： | 1 |
| 16 | Stable carbon isotopic fractionation of individual n-alkanes accompanying primary migration: Evidence from hydrocarbon generation-expulsion simulation of selected terrestrial source rocks显示文摘 | l iao Y H Geng A S | 2009 | Applied Geochemistry2009，24，： | 1 |
| 17 | Fast multipole method for scattering from an arbitrary PEC target above or buried in a lossy half space 显示文摘 | Geng N Sullivan A Carin L | 2001 | IEEE Transactions on Antennas and Propagation2001，49，5： | 1 |
| 18 | Kinetic-simulating experiment combined with GC-IRMS analysis: Application to identification and assessment of coal-derived methane from Zhongba Gas Field(Sichuan Basin, China) 显示文摘 | Xiong Y Q Geng A S Liu J Z | 2004 | Chem Geol2004，213，4： | 1 |
| 19 | A Sender - Receiver Framework for Knowledge Transfer显示文摘 | Lin L Geng X Whinston A B | 2005 | MIS Quarterly2005，29，2： | 1 |
| 20 | Effects of dietary coenzyme Q10 supplementation on hepatic mitochondrial function and the activities of respiratory chainrelated enzymes in ascitic broiler chickens显示文摘 | Geng A L Guo Y M | 2005 | Br Poult Sci2005，46，5： | 1 |
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