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1篇 您的检索式:作者名="Gavin R. SCREATON"
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1Following a TRAIL: Update on a ligand and its five receptors显示文摘Identification of tumour necrosis factor apoptosis inducing ligand (TRAIL), a TNF family ligand, sparked a torrent of research, following an initial observation that it could kill tumour cells, but spare normal cells. Almost a decade after its discovery, and with five known receptors, the true physiological role of TRAIL is still debated and its anti-tumorigenic properties limited by potential toxicity. This review takes a comprehensive look at the story of this enigmatic ligand, addressing its remaining potential as a therapeutic and providing an overview of the TRAIL receptors themselves.Fiona C. KIMBERLEY Gavin R. SCREATON 2004Cell Research2004,14,5:26
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