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| 1 | How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes显示文摘在学习 mRNA 表示的一个关键假设是它在蛋白质表示的预言是增进知识的。然而,仅仅有限的研究在酵母探索了 mRNA 蛋白质表示关联或人的纸巾和结果是相对不一致的。我们从 30 个无关的女人在刚孤立的人的传播单核白血球在 mRNA 蛋白质表情上执行了关联分析。为 71 基因的表示蛋白质被确定并且由结合的 2-D 电气泳动识别了集体 spectrometry。相应 mRNA 表达式被 Affymetrix 基因芯片确定。重要关联(r=0.235, P < 0.0001 ) 包括所有学习基因和所有样品为整个数据集被观察。关联在基因本体论的不同生物范畴变化了。例如,最高的关联以细胞的部件为细胞外的区域的基因被完成(r=0.643, P < 0.0001 ) 并且最低关联为规定的基因被获得(r=0.099, P=0.213 ) 以生物过程。在染色体,样品的一半证明为 71 基因的重要积极关联和重要关联在所有样品在平均 mRNA 和平均蛋白质表示层次之间被发现(r=0.296, P < 0.01 ) 。在学习组水平,然而,仅仅五学习基因越过所有样品有重要积极关联。我们的结果显示出在 mRNA 和蛋白质表示层次之间的全面积极关联。然而,中等、变化的关联建议那 mRNA 表情可能有时是有用的,但是远非当然在预言蛋白质表示层次完善。 | Yanfang Guo Peng Xiao Shufeng Lei Feiyan Deng Gary Guishan Xiao Yaozhong Liu Xiangding Chen Liming Li Shan Wu Yuan Chen Hui Jiang Lijun Tan Jingyun Xie Xuezhen Zhu Songping Liang Hongwen Deng | 2008 | Acta Biochimica et Biophysica Sinica2008,40,5: | 7 |
| 2 | Rapid Detection of Wheat Blast Pathogen Magnaporthe oryzae Triticum Pathotype Using Genome-Specific Primers and Cas12a-mediated Technology显示文摘Wheat blast,caused by the fungus Magnaporthe oryzae Triticum(MoT)pathotype,is a devastating disease persistent in South America and Bangladesh.Since MoT generally fails to cause visual symptoms in wheat until the heading stage when the infection would have advanced,disease control by fungicide application solely based on the detection of visual symptoms is ineffective.To develop an accurate and sensitive method to detect MoT at the seedling and vegetative stages for disease control,we sequenced the genomes of two MoT isolates from Brazil and identified two DNA fragments,MoT-6098 and MoT-6099,that are present in the MoT genome but not in the genome of the rice-infecting Magnaporthe oryzae Oryzae(MoO)pathotype.Using polymerase chain reaction(PCR),we confirmed the specificity of the two markers in 53 MoT and MoO isolates from South America and Bangladesh.To test the efficiency of the two markers,we first established a loop-mediated isothermal amplification(LAMP)method to detect MoT at isothermal conditions,without the use of a PCR machine.Following this,we used the Cas12a protein and guide RNAs(gRNAs)to target the MoT-6098 and MoT-6099 sequences.The activated Cas12a showed indiscriminate single-stranded deoxyribonuclease(ssDNase)activity.We then combined targetdependent Cas12a ssDNase activation with recombinase polymerase amplification(RPA)and nucleic acid lateral flow immunoassay(NALFIA)to develop a method that accurately,sensitively,and cost-effectively detects MoT-specific DNA sequences in infected wheat plants.This novel technique can be easily adapted for the rapid detection of wheat blast and other important plant diseases in the field. | Houxiang Kang Ye Peng Kangyu Hua Yufei Deng Maria Bellizzi Dipali Rani Gupta Nur Uddin Mahmud Alfredo S.Urashima Sanjoy Kumar Paul Gary Peterson Yilin Zhou Xueping Zhou Md Tofazzal Islam Guo-Liang Wang | 2021 | Engineering2021,7,9: | 4 |
| 3 | KIAP, a Novel Member of the Inhibitor of Apoptosis Protein Family显示文摘 | Jiing-Huey Lin Gary Deng Qihong Huang John Morser | 2000 | Biochemical and Biophysical Research Communications2000,,3: | 1 |
| 4 | Single-crystal sapphire fiber-based strain sensor for high-temperature applications显示文摘 | Hai xiao Jiangdong Deng Gary Pickrell | 2003 | Journal of Lightwave Technology2003,21,10: | 1 |
| 5 | Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation显示文摘 | Valdeci da Cunha Doris M. Tham Baby Martin-McNulty Gary Deng Jerrick J. Ho Dennis W. Wilson John C. Rutledge Ronald Vergona Mark E. Sullivan Yi-Xin (Jim) Wang | 2004 | Atherosclerosis2004,,1: | 1 |
| 6 | KIAP, anovel member of the apotosis protein Family 显示文摘 | Jiing-Huey Lin Gary Deng Qihong Huang | 2000 | Biochemical and Biophysical Research Communications2000,279,: | 1 |
| 7 | The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation显示文摘 | Kazuhisa Nakashima Xin Zhou Gary Kunkel Zhaoping Zhang Jian Min Deng Richard R. Behringer Benoit de Crombrugghe | 2002 | Cell2002,,1: | 1 |
| 8 | A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects显示文摘 | Gary Deng Hong Lin Andrew Seidman Monica Fornier Gabriella D'Andrea Kathleen Wesa Simon Yeung Susanna Cunningham-Rundles Andrew J. Vickers Barrie Cassileth | | Journal of Cancer Research and Clinical Oncology0,,: | 1 |
| 9 | Explaining spatial convergence of China's industrial productivity 显示文摘 | Deng Paul Gary Jefferson | 2011 | Oxford Bulletin of Eco- nomics and Statistics2011,73,6: | 1 |
| 10 | A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients:immunological effects显示文摘 | DENG GARY LIN HONG | 2009 | J Cancer Res Clin Oneol2009,135,: | 1 |
| 11 | Characterization of a small molecule PAI-1 inhibitor, ZK4044显示文摘 | Amy Liang Faye Wu Kathy Tran Steven W. Jones Gary Deng Bin Ye Zhuchun Zhao R. Michael Snider William P. Dole John Morser Qingyu Wu | 2004 | Thrombosis Research2004,,4: | 1 |
| 12 | Laparoscopic linear cutting stapler failure显示文摘 | Donna Y Deng Maxwell V Meng Hiep T Nguyen Gary C Bellman Marshall L Stoller | 2002 | Urology2002,,3: | 1 |
| 13 | Single crystal sapphire fiber based strain sensor for high temperature applications显示文摘 | Hai Xiao Jiang-dong Deng Gary P ickrell | 2003 | Journal of Lightwave Technology2003,21,10: | 1 |
| 14 | A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects显示文摘 | Gary Deng Hong Lin Andrew Seidman Monica Fornier Gabriella D’Andrea Kathleen Wesa Simon Yeung Susanna Cunningham-Rundles Andrew J. Vickers Barrie Cassileth | 2009 | Journal of Cancer Research and Clinical Oncology2009,,9: | 1 |
| 15 | A phase I/II trial ofa polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects显示文摘 | Gary Deng Hong Lin Andrew Seidman | 2009 | Journal of Cancer Research and Clinical Oncology2009,135,: | 1 |
| 16 | KIAP, a Novel Member of the Inhibitor of Apoptosis Protein Family显示文摘 | Jiing-Huey Lin Gary Deng Qihong Huang John Morser | 2000 | Biochemical and Biophysical Research Communications2000,,3: | 1 |
| 17 | Composition-tailored synthesis of gradient transition metal precursor particles for lithium-ion battery cathode materials 显示文摘 | GARY M K LLIAS B DENG H X | 2011 | Journal of Chemistry Materials2011,23,7: | 1 |
| 18 | Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant显示文摘It has been more than 3 years since the novel coronavirus(SARS-CoV-2)pandemic raged globally.The coronavirus disease 2019(COVID-19)has greatly influenced human society.According to data from the World Health Organization(WHO),there were over 656 million confirmed cases of COVID-19 in the world as of January 1,2023,including over 6.6 million deaths[1]. | Rong-Meng Jiang Zheng-De Xie Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-Xiao Shang Bao-Ping Xu Zhi-Sheng Liu Gen Lu Ji-Kui Deng Guang-Hua Liu Xiao-Chuan Wang Jian-She Wang Lu-Zhao Feng Wei Liu Yi Zheng Sai-Nan Shu Min Lu Wan-Jun Luo Miao Liu Yu-Xia Cui Le-Ping Ye A-Dong Shen Gang Liu Li-Wei Gao Li-Juan Xiong Yan Bai Li-Kai Lin Zhuang Wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao Jian-Bo Shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-Ling Shen | 2024 | World Journal of Pediatrics2024,20,3: | 0 |
| 19 | Nanocomposite membranes with high-charge and size-screened phosphorylated nanocellulose fibrils for CO_(2)separation显示文摘In this study,cellulose nanofibrils(CNF)of high charge(H-P-CNF)and screened size(H-P-CNF-S)were fabricated by increasing the charge of phosphorylated cellulose nanofibrils(P-CNFs)during the pre-treatment step of CNF production.Results show that the H-P-CNF have a significantly higher charge(3.41 mmol g^(-1))compared with P-CNF(1.86 mmol g^(-1)).Centrifugation of H-P-CNF gave a supernatant with higher charge(5.4 mmol g^(-1))and a reduced size(H-P-CNF-S).These tailored nanocelluloses were added to polyvinyl alcohol(PVA)solutions and the suspensions were successfully coated on porous polysulfone(PSf)supports to produce thin-film nanocomposite membranes.The humid mixed gas permeation tests show that CO_(2)permeability increases for membranes with the addition of H-P-CNF-S by 52%and 160%,compared with the P-CNF/PVA membrane and neat PVA membrane,respectively. | Ragne Marie Lilleby Helberg Jonathan Ø.Torstensen Zhongde Dai Saravanan Janakiram Gary Chinga-Carrasco Øyvind W.Gregersen Kristin Syverud Liyuan Deng | 2021 | Green Energy & Environment2021,6,4: | 0 |
| 20 | Global Pediatric Pulmonology Alliance(GPPA)proposal for COVID-19 vaccination in children显示文摘Coronavirus disease 2019(COVID-19)remains a global epidemic.As of August 18,2021,the number of reported cases has exceeded 207 million globally,with more than 4.3 million deaths.COVID-19 has brought devastating losses to human society.The overall crude mortality rate is 1-3%.Although pediatric deaths from COVID-19 are rare,they do occur,as over 9,000 children have died from COVID-19 globally to date[1].With the gradual and broad application of COVID-19 vaccines around the world,the rising proportion of cases among children and unvaccinated young adults demands attention.According to World Health Organization surveillance data. | Lance E.Rodewald Kun-Ling Shen Yong-Hong Yang Gary Wing-Kin Wong Leyla Namazova-Baranova Lanny J.Rosenwasser Adel S.Alharbi Anne B.Chang Jim Buttery Basil Elnazir Ruth A.Etzel Anne Goh Hilary Hoey Rosemary Home Eitan Kerem Antonella Muraro Chris O’Callaghan Kazunobu Ouchi Varinder Singh Jiu-Yao Wang Spencer Li Yu Guanon Yue-Jie Zheng Zhengde Xie Gen Lu Yi Jiang Xing-Wang Li Rong-Meng Jiang Xiao-Chuan Wang Ji-Kui Deng Xiao-Xia Lu Bao-Ping Xu Zhuang Wei Lu-Zhao Feng Zheng-Yan Zhao the Global Pediatric Pulmonology Alliance(GPPA)Counci Global Pediatric Pulmonology Alliance(GPPA)Expert Panel on Infectious Diseases and COVID-19 | 2021 | World Journal of Pediatrics2021,17,5: | 0 |