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| 1 | Tumor-associated myeloid cells:diversity and therapeutic targeting显示文摘Myeloid cells in tumor tissues constitute a dynamic immune population characterized by a non-uniform phenotype and diverse functional activities.Both tumor-associated macrophages(TAMs),which are more abundantly represented,and tumor-associated neutrophils(TANs)are known to sustain tumor cell growth and invasion,support neoangiogenesis and suppress anticancer adaptive immune responses.In recent decades,several therapeutic approaches have been implemented in preclinical cancer models to neutralize the tumor-promoting roles of both TAMs and TANs.Some of the most successful strategies have now reached the clinic and are being investigated in clinical trials.In this review,we provide an overview of the recent literature on the evergrowing complexity of the biology of TAMs and TANs and the development of the most promising approaches to target these populations therapeutically in cancer patients. | Alberto Mantovani Federica Marchesi Sebastien Jaillon Cecilia Garlanda Paola Allavena | 2021 | Cellular & Molecular Immunology2021，18，3： | 9 |
| 2 | Tumor associated macrophages and neutrophils in cancer显示文摘 | Maria Rosaria Galdiero Eduardo Bonavita Isabella Barajon Cecilia Garlanda Alberto Mantovani Sébastien Jaillon | 2013 | Immunobiology2013，，： | 2 |
| 3 | Pathways connecting in-flammation and cancer显示文摘 | Allavena P Garlanda C Borrello MG | 2008 | Curr Opin Genet Dev2008，18，1： | 1 |
| 4 | Pentraxins and atheros-clerosis :the role of PTX3 显示文摘 | Garlanda C Bottazzi B Moalli F | 2011 | Curr Pharm Des2011，17，1： | 1 |
| 5 | The interleukin-1 family : back to the future显示文摘 | Garlanda C Dinarello CA Mantovani A | 2013 | Immunity2013，39，6： | 1 |
| 6 | Pentraxins in innateimmunity:fromC-reactive protein to the long pentraxin PTX3显示文摘 | Mantovani Garlanda DonI | 2008 | Clinlmmunoi2008，28，1： | 1 |
| 7 | Pentraxins at the crossroads be- tween innate immunity, inflammation, matrix deposition, and female fertili-ty显示文摘 | Garlanda C Bottazzi B Bastone A | 2005 | Annual review of immunology2005，23，4： | 1 |
| 8 | The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance显示文摘 | Allavena P Sica A Garlanda C | 2008 | Immunol Rev2008，222，： | 1 |
| 9 | Membrane and soluble pattern recognition receptors: unique functions of the long pentraxin PTX3 显示文摘 | MONTOVANI A GARLANDA C OTERO K | 2004 | Clin Exp All Rev2004，2，4： | 1 |
| 10 | Inflammation-mediated promotion of invasion and metastasis显示文摘 | Graziella Solinas Federica Marchesi Cecilia Garlanda Alberto Mantovani Paola Allavena | 2010 | Cancer and Metastasis Reviews2010，，2： | 1 |
| 11 | Non-redundant role of the long pentraxin 3 PTX3 in anti-fungal innate immune response显示文摘 | Garlanda C Hirsch E Bozza S | 2002 | Nature2002，420，： | 1 |
| 12 | Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family 显示文摘 | Garlanda C Riva F Polentarutti N | 2004 | Proe Natl Aead Sei USA2004，101，10： | 1 |
| 13 | Pentraxin 3, a non-redundant sol- uble pattern recognition receptor involved in innate immunity显示文摘 | Mantovani A Garlanda C Bottazzi B | 2001 | Vac- cine2001，21，2： | 1 |
| 14 | The long pentraxin FFX3 : a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases 显示文摘 | Norata GD Garlanda C Catapano AL | 2010 | Trends Cardiovasc Med2010，20，1： | 1 |
| 15 | Central role for G pro- tein-coupled phosphoinositide 3-kinase gamma in inflammation显示文摘 | Hirsch E Katanaev VL Garlanda C | 2000 | Sci- ence2000，287，5455： | 1 |
| 16 | Pentraxins at the crossroads between innate immunity,inflammation,matrix deposition,and female fertility显示文摘 | Garlanda C Bottazzi B Bastone A | 2005 | Annu Rev Immunol2005，23，： | 1 |
| 17 | The long pentraxin PTX3 :a modulator of the immunoinflammatory response in atheroscle-rosis and cardiovascular diseases 显示文摘 | Norata GD Garlanda C Catapano AL | 2010 | Trends Cardiovasc Med2010，20，2： | 1 |
| 18 | Increased susceptibility to colitis-associatedcancer of mice lacking TIR8,an inhibitory member of the in-terleukin-1 receptor family显示文摘 | Garlanda C Riva F Veliz T Polentarutti N Pasqualini F Radaelli E Sironi M Nebuloni M Zorini EO Scanziani E Mantovani A | 2007 | Cancer Res2007，67，13： | 1 |
| 19 | The long pentraxin PTX3 : a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases 显示文摘 | Norata GD Garlanda C Catapano AL | 2010 | Trends Cardiovasc Med2010，20，2： | 1 |
| 20 | The long pentraxin PTX3:a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases显示文摘 | Norata GD Garlanda C Catapano AL | 2010 | Trends Cardiovasc Med2010，20，2： | 1 |
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