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| 1 | C_(19)-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities显示文摘Eight new C_(19)-diterpenoid alkaloid arabinosides, named aconicarmichosides E–L(1–8), were isolated from an aqueous extract of the lateral roots of Aconitum carmichaelii(Fu Zi). Their structures were determined by spectroscopic and chemical methods including 2D NMR experiments and acid hydrolysis. Compounds 1–8, together with the previously reported four neoline 14-O-arabinosides from the same plant, represent the only examples of glycosidic diterpenoid alkaloids so far. At a dose of 1.0 mg/kg(i.p.), as compared with the black control, compounds 1, 2, and 4–6 exhibited analgesic effects with 465.6% inhibitions against acetic acid-induced writhing of mice. Structure–activity relationship was also discussed. | Qinglan Guo Huan Xia Xianhua Meng Gaona Shi Chengbo Xu Chenggen Zhu Tiantai Zhang Jiangong Shi | 2018 | Acta Pharmaceutica Sinica B2018，8，3： | 12 |
| 2 | Effectiveness of a microabrasion technique using 16% HCL with manual application on fluorotic teeth: A series of studies显示文摘BACKGROUND Dental fluorosis is caused by excessive fluoride ingestion during tooth formation.As a consequence,there is a higher porosity on the enamel surface,which causes an opaque look.AIM The aim of this study was to identify a dental intervention to improve the smile in patients with tooth fluorosis.Additional aims were to relate the stain size on fluorotic teeth with the effectiveness of stain removal,enamel loss and procedure time using a manual microabrasion technique with 16%hydrochloric acid(HCL).METHODS An experimental study was carried out on 84 fluorotic teeth in 57 adolescent patients,33 females and 24 males,with moderate to severe fluorosis.The means,standard deviations and percentages were analyzed using nonparametric statistics and ArchiCAD 15 software was used for the variables including stain size and effectiveness of stain removal.RESULTS The average enamel loss was 234μm and was significantly related to the procedure time categorized as 1-4 min and 4.01-6 min,resulting in a P>0.000.The microabrasion technique using 16%HCL was effective in 90.6%of patients and was applied manually on superficial stains in moderate and severe fluorosis.Procedure time was less than 6 min and enamel loss was within the acceptable range.CONCLUSION Microabrasion is a first-line treatment;however,the clinician should measure the average enamel loss to ensure that it is within the approximate range of 250μm in order to avoid restorative treatment. | Martina Nevárez-Rascón Nelly Molina-Frechero Edith Adame Ethel Almeida Uriel Soto-Barreras Enrique Gaona Alfredo Nevárez-Rascón | 2020 | World Journal of Clinical Cases2020，8，4： | 2 |
| 3 | Reactivation of herpes virus-6 in a chronic myeloyd leukemia (CML) patient during treatment with dasatinib 显示文摘 | Garcia-Munoz R Ruiz de Gaona E Rodriguez-Otero P | 2007 | Haematologica2007，92，2： | 1 |
| 4 | The lactation curve in the Mediterranean buffallo and its crosses显示文摘 | BRAMMER GAONA J H PEREIRA C S DE V J | 1986 | Anim Breed Abstr1986，，： | 1 |
| 5 | The-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagu- lated patients 显示文摘 | MONTES R RUIZ DE GAONA E MARTINEZ-GONZALEZ M A | 2006 | Br J Haematol2006，133，2： | 1 |
| 6 | Algebraic decision diagrams and their applications 显示文摘 | Bachar R I Frohm E A Gaona C M Hachtel G D Macii E Pardo A Somenzi F | 1997 | Formal Methods in Systems Design1997，10，23： | 1 |
| 7 | Distribution of mast cells in mammary gland stroma,during the active and inactive periods in the bitch显示文摘 | Gaona H V Lavielle R E Arce S R A | 1999 | Veterinaria Mexico1999，30，4： | 1 |
| 8 | Nanostructured Titania/Hydroxyapatite Composite Coatings Deposited by High Velocity Oxy-fuel (HVOF) Spraying显示文摘 | GAONA M LIMA R S MARPLE B R | 2007 | Materials Science and Engineering A2007，458，12： | 1 |
| 9 | Algebraic decision diagrams and their applications 显示文摘 | Bahar B I Frohm E A Gaona C M | 1997 | Formal Methods in System Design1997，10，23： | 1 |
| 10 | Location and detection of explosive-contaminated human fingerprints on distant targets using standoff laser-induced breakdown spectrosco- py显示文摘 | Lucena P Gaona I Moros J | 2013 | Spectrochimica Acta Part B2013，85，： | 1 |
| 11 | Positive effects on game species of top predators by controlling smaller predator populations:an example with lynx,mongooses,and rabbits显示文摘 | Palomares F Gaona P Ferreras P | | 0，，： | 1 |
| 12 | Phylogenetic and structural information on glyceraldehyde-3-phosphate dehydrogenase (G3PDH) in Plasmodium provides functional insights显示文摘 | Sheila Akinyi Jenny Gaona Esmeralda V.-S. Meyer John W. Barnwell Mary R. Galinski Vladimir Corredor | 2007 | Infection, Genetics and Evolution2007，，2： | 1 |
| 13 | Prenatal diagnosis of neurofibromatosis type I: From flanking RFLPs to intragenic microsatellite markers显示文摘 | Lazaro C Gaona A Ravella A | 1995 | Prenat Diagn1995，15，2： | 1 |
| 14 | Spatiotemporal dyna- mics of electrocorticographic high gamma activity during overt and covert word repetition 显示文摘 | Pei X Leuthardt EC Gaona CM | 2011 | Neuroimage2011，54，： | 1 |
| 15 | Neurofibromatosis type 1 due to germ-line mosaicism in a clinically normal father显示文摘 | L(a)zaro C Ravella A Gaona A | | 0，，21： | 1 |
| 16 | Distribution of mast cells in mammary gland stroma,during the active and inactive periods in the bitch显示文摘 | Gaona H V Lavielle R E Arce S R A | 1999 | Veterinaria Mexico1999，30，4： | 1 |
| 17 | Algebraic decision diagrams and their applications显示文摘 | BACHAR R I FROHM E A GAONA C M | 1997 | Formal Methods in Systems Design1997，10，23： | 1 |
| 18 | Characterization of the Azotobacter vinelandii algC gene involved in alginate and lipopolysaccharide production 显示文摘 | GAONA G NUAEZ C GOLDBERG J B | 2004 | FEMS Microbiology Letters2004，238，： | 1 |
| 19 | Corrosion Behaviour of a New Low-Nickel Stainless Steel Reinforcement: A Study in Simulated Pore Solutions and in Fly Ash Mortars显示文摘 | M. Criado S. Fajardo J. M. Bastidas Citlalli Gaona Tiburcio | 2012 | International Journal of Corrosion2012，，： | 1 |
| 20 | Determination of mercury in polluted soils surrounding a chlor alkali plant Direct speciation by X-ray absorption speetros copy techniques and preliminary geochemical characterisa tion of the area显示文摘 | Anna Bernaus Xavier Gaona Derk van Ree | 2006 | Analytica Chimica Aeta2006，565，： | 1 |
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