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| 1 | Is aggressive intravenous fluid resuscitation beneficial in acute pancreatitis? A meta-analysis of randomized control trials and cohort studies显示文摘BACKGROUND There is conflincting evidence on the intravenous fluid(IVF)strategy for acute pancreatitis(AP).We perform a metaanalysis of the available evidence.AIM To investigate if aggressive IVF therapy in AP patients is beneficial to decrease mortality and improve outcomes.METHODS Metaanalysis of available randomized controlled trials and cohort studies comparing aggressive IVF vs non-aggressive IVF resuscitation.RESULTS There was no significant difference in mortality between the aggressive(n=1229)and non-aggressive IVF(n=1397)patients.Patients receiving aggressive IVF therapy had higher risk for acute kidney injury and acute respiratory distress syndrome.There also was no significant difference in the overall incidence of systemic inflammatory response syndrome,persistent organ failure,pancreatic necrosis when comparing both study groups.CONCLUSION Early aggressive IVF therapy did not improve mortality.Moreover,aggressive IVF therapy could potentially increase the risk for acute kidney injury and pulmonary edema leading to respiratory failure and mechanical ventilation.Studies are needed to investigate which subset of AP patients could benefit from aggressive IVF therapy. | Mohamed M Gad C.Roberto Simons-Linares | 2020 | World Journal of Gastroenterology2020,26,10: | 18 |
| 2 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017,23,38: | 15 |
| 3 | 显示文摘 | Hamed A M El-Sharkawy I I | 2001 | Rene wable Energy2001,22,4: | 1 |
| 4 | Water content, organic carbon and dry bulk density in flooded sediments显示文摘 | Avnimelech Y Gad R Leon E M | 2001 | Aquacultural engineering2001,25,: | 1 |
| 5 | Ascorbic acid enhances arsenic trioxide induced cytotoxicity inmuhiplemyeloma cells显示文摘 | Gad M Bahlis N J Reis I | | 0,,: | 1 |
| 6 | The use of wood pulp and radiation modified starch in wastewater treatment显示文摘 | Abdel Aal S E Gad Y Dessouki A M | 2006 | J Appl Polym Sci2006,99,5: | 1 |
| 7 | Could heat shock transcription factors function as hydrogen peroxide sensors in plants显示文摘 | Gad M Ron M | 2006 | Annals of Botany2006,98,: | 1 |
| 8 | Analysis of longitudinal data with intermittent missing values using the stochastic EM algorithm显示文摘 | Gad A M Ahmed A S | 2005 | Computational Statistics and Data Analysis2005,50,10: | 1 |
| 9 | Axis development:the mouse becomes a dachshund显示文摘 | Gad J M Tam P P | 1999 | Curr Biol1999,9,20: | 1 |
| 10 | The spatial and temporal expression patterns of netrin receptors,DCC and Neogenin,in the developing mouse retina显示文摘 | Gad J M Keeling S L Shu T | 2000 | Exp Eye Res2000,70,6: | 1 |
| 11 | Water content,organic carbon and dry bulk density in flooded sediments 显示文摘 | Avnimelech Y Gad R Leon E M | 2001 | Aquacultural engineering2001,25,1: | 1 |
| 12 | Cord blood re-sistin and adiponectin in term newborns of diabetic moth-ers显示文摘 | Mohamed M H Gad G I Ibrahim HY | 2010 | Arch Med Sci2010,6,4: | 1 |
| 13 | Thermal and thermooxidative degradation of poly(ethylene oxide)-metal salt complexes显示文摘 | Costa L Gad A M Camino G | 1992 | Macromolecules1992,25,: | 1 |
| 14 | Preoperative segmental localization of hepatic metastases:utility of three-dimensional CT during arterial portography显示文摘 | Soyer P Roche A Gad M | 1991 | Radiology1991,180,3: | 1 |
| 15 | Radiologically assessed testicular changes in infertile males with varicocele 显示文摘 | Hassan A Gad H M Mostafa T | 2011 | Andrologia2011,43,5: | 1 |
| 16 | Modal analysis of steelframed residential structures for application to seismic design 显示文摘 | Gad E F Chandler A M | 2001 | Journal of Vibration and Control2001,17,1: | 1 |
| 17 | The fluid mechanics of microdevices- the Freeman scholar lecture 显示文摘 | M Gad el Hak | 1999 | ASME Journal of Fluids Engineering1999,121,: | 1 |
| 18 | Elasticand shear modul of single - walled carbon nanotube ropes 显示文摘 | Salvetat J P Briggs GAD Bonard J M | 1999 | Physical Review Letters1999,82,5: | 1 |
| 19 | Thiamin confers enhanced tolerance to oxidative stress in Arabidopsis 显示文摘 | Meral T-O Gad M Luhua S | 2009 | Plant Physiology2009,151,1: | 1 |
| 20 | Protective role of nitric oxide in indomethacin-induced gastric ulceration by a mechanism independent of gastric acid secretion 显示文摘 | Khattab M M Gad M Z Abdallah D | 2001 | Pharmacol Res2001,43,: | 1 |