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| 1 | Incremental value of magnetic resonance neurography of Lumbosacral plexus over non-contributory lumbar spine magnetic resonance imaging in radiculopathy: A prospective study显示文摘AIM: To test the incremental value of 3T magnetic resonance neurography(MRN) in a series of unilateral radiculopathy patients with non-contributory magnetic resonance imaging(MRI).METHODS: Ten subjects(3 men,7 women; mean age54 year and range 22-74 year) with unilateral lumbar radiculopathy and with previous non-contributory lumbar spine MRI underwent lumbosacral(LS) plexus MRN over a period of one year. Lumbar spine MRI performed as part of the MRN LS protocol as well as bilateral L4-S1 nerves,sciatic,femoral and lateral femoral cutaneous nerves were evaluated in each subject for neuropathy findings on both anatomic(nerve signal,course and caliber alterations) and diffusion tensor imaging(DTI)tensor maps(nerve signal and caliber alterations).Minimum fractional anisotropy(FA) and mean apparent diffusion coeffcient(ADC) of L4-S2 nerve roots,sciatic and femoral nerves were recorded.RESULTS: All anatomic studies and 80% of DTI imaging received a good-excellent imaging quality grading. In a blinded evaluation,all 10 examinations demonstrated neural and/or neuromuscular abnormality corresponding to the site of radiculopathy. A number of contributory neuropathy findings including double crush syndrome were observed. On DTI tensor maps,nerve signal and caliber alterations were more conspicuous. Although individual differences were observed among neuropathic appearing nerve(lower FA and increased ADC) as compared to its contralateral counterpart,there were no significant mean differences on statistical comparison of LS plexus nerves,femoral and sciatic nerves(P > 0.05).CONCLUSION: MRN of LS plexus is useful modality for the evaluation of patients with non-contributory MRI of lumbar spine as it can incrementally delineate the etiology and provide direct objective and non-invasive evidence of neuromuscular pathology. | Avneesh Chhabra Sahar J Farahani Gaurav K Thawait Vibhor Wadhwa Allan J Belzberg John A Carrino | 2016 | World Journal of Radiology2016，8，1： | 4 |
| 2 | 3T magnetic resonance neurography of pudendal nerve with cadaveric dissection correlation显示文摘AIM: To evaluate the pudendal nerve segments that could be identified on magnetic resonance neurography(MRN) before and after surgical marking of different nerve segments.METHODS: The hypothesis for this study was that pudendal nerve and its branches would be more easily seen after the surgical nerve marking. Institutional board approval was obtained. One male and one female cadaver pelvis were obtained from the anatomy board and were scanned using 3 Tesla MRI scanner using MR neurography sequences. All possible pudendal nerve branches were identified. The cadavers were then sent to the autopsy lab and were surgically dissected by a peripheral nerve surgeon and an anatomist to identify the pudendal nerve branches. Radiological markers were placed along the course of the pudendal nerve and its branches. The cadavers were then closed and rescanned using the same MRN protocol as the premarking scan. The remaining pudendal nerve branches were attempted to be identified using the radiological markers. All scans were read by an experienced musculoskeletal radiologist.RESULTS: The pre-marking MR Neurography scans clearly showed the pudendal nerve at its exit from the lumbosacral plexus in the sciatic notch, at the level of the ischial spine and in the Alcock's Canal in both cadavers. Additionally, the right hemorrhoidal branch could be identified in the male pelvis cadaver. The perineal and distal genital branches could not be identified. On post-marking scans, the markers were used as identifiable structures. The location of the perineal branch, the hemorroidal branch and the dorsal nerve to penis(in male cadaver)/clitoris(in female cadaver) could be seen. However, the visualization of these branches was suboptimal. The contralateral corresponding nerves were poorly seen despite marking on the surgical side. The nerve was best seen on axial T1W and T2W SPAIR images. The proximal segment could be seen well on 3D DW PSIF sequence. T2W SPACE was not very useful in visualization of this small nerve or its branches.CONCLUSION: Proximal pudendal nerve is easily seen on MR neurography, however it is not possible to identify distal branches of the pudendal nerve even after surgical marking. | Avneesh Chhabra Courtney A McKenna Vibhor Wadhwa Gaurav K Thawait John A Carrino Gary P Lees A Lee Dellon | 2016 | World Journal of Radiology2016，8，7： | 3 |
| 3 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 4 | Impact at nalysis of biodiesel on engine performance : A review 显示文摘 | Gaurav Dwivedi J Siddharth A M P Sharm | 2011 | Re1 ble and Sustainable Energy Reviews2011，15，46： | 1 |
| 5 | A comparative study of tolerance analysis methods显示文摘 | HEN Zhengshu GAURAV A JAMI J S | 2005 | Journal of Computing and Information Science in Engineering2005，5，3： | 1 |
| 6 | Quantitative structure activity relationship and design of phenyl alkyl ketone derivatives as in- hibitors of phosphodiesterase 4 显示文摘 | Gaurave A Gautam V Singh R | 2014 | Current Enzyme Inhibition2014，10，1： | 1 |
| 7 | A review on development of solid phase microextraction fibers by sol-gel methods and their applications显示文摘 | Kumar A Gaurav Malik AK | 2008 | Anal Chim Acta2008，610，1： | 1 |
| 8 | Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial显示文摘 | John J Bissler J Christopher Kingswood El?bieta Radzikowska Bernard A Zonnenberg Michael Frost Elena Belousova Matthias Sauter Norio Nonomura Susanne Brakemeier Petrus J de Vries Vicky H Whittemore David Chen Tarek Sahmoud Gaurav Shah Jeremie Lincy David | 2013 | The Lancet . 2013 (9869)2013，，： | 1 |
| 9 | State of the art in hard turning显示文摘 | BARTARY A Gaurav CHOUDHURY S K | 2012 | International Journal of Machine Tools & Manufacture2012，，53： | 1 |
| 10 | Cardiovascular dysfunc- tionin symptomatic pfimaryhyperparathyroidism and its re- versalafter curative parathyroidectomy : Results of a prospective case controlstudy 显示文摘 | Gaurav A Gitika N Aditya K | 2013 | Surgery2013，154，： | 1 |
| 11 | Beam type hexapod structure based six component force-torque sensor显示文摘 | DWARAKANATH T A GAURAV B | 2011 | Mechatronics2011，21，8： | 1 |
| 12 | Water enhancement of COz conversion on silver in 1-ethyl-3-methylimidazolium tetrafluoroborate 显示文摘 | Brian A R Wei Zhu Gaurav K | 2013 | Journal of The Electrochemical Society2013，160，2： | 1 |
| 13 | CanJiac resynchronization in patients with atrial fibrillation : A Meta-analysis of prospective cohort studies 显示文摘 | Gaurav A Niteebh K | 2008 | J Am Coll Cardiol2008，52，： | 1 |
| 14 | 3D-QSAR studies of 4-quinolone derivatives as high-affinity ligands at the benzodiazepine site of brain GABAA receptors显示文摘 | Gaurav A Yadav MR Giridhar R | 2011 | Med Chem Res2011，20，2： | 1 |
| 15 | Predictive factor analysisfor successful performance of iris recognition-assisted dynamicrotational eye tracking during laser in situ keratomileusis 显示文摘 | Gaurav P Dhivya AK Amar A | 2010 | Am J Ophthalmol2010，149，： | 1 |
| 16 | A review development of solid phase micro extraction fibers by sol-gel method and their applications显示文摘 | Kaurav A Gaurav Malik A K | 2008 | Analytica Chimica Acta2008，610，1： | 1 |
| 17 | Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial显示文摘 | David Neal Franz Elena Belousova Steven Sparagana E Martina Bebin Michael Frost Rachel Kuperman Olaf Witt Michael H Kohrman J Robert Flamini Joyce Y Wu Paolo Curatolo Petrus J de Vries Vicky H Whittemore Elizabeth A Thiele James P Ford Gaurav Shah Helene | 2012 | The Lancet2012，，： | 1 |
| 18 | Calcitriol decreases expression of importin ɑ3 and attenuates relA translocation in human bronchial amooth muscle cells显示文摘 | Tanuprlya A Gaurav KG Devendra KA | 2012 | J Clin Immunol2012，32，9： | 1 |
| 19 | Effect of Polymer Blending on the Release of Ganeielovir from PLGA Microspheres 显示文摘 | Duvvuri Gaurav Janoria K Mitra A K | 2005 | Pharm Res2005，6，： | 1 |
| 20 | Decision framework for the analysis of green supply chain contracts: An evolutionary game approach 显示文摘 | SIKHAR BARARI GAURAV AGARWAL ZHANG W J A | 2012 | Expert Systems with Applica- tions2012，，39： | 1 |
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