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| 1 | Gastric low-grade mucosal-associated lymphoid tissue-lymphoma: Helicobacter pylori and beyond显示文摘The stomach is the most frequently involved site for extranodal lymphomas,accounting for nearly two-thirds of all gastrointestinal cases.It is widely accepted that gastric B-cell,low-grade mucosal-associated lymphoid tissue(MALT)-lymphoma is caused by Helicobacter pylori(H.pylori)infection.MALT-lymphomas may engender different clinical and endoscopic patterns.Often,diagnosis is confirmed in patients with only vague dyspeptic symptoms and without macroscopic lesions on gastric mucosa.H.pylori eradication leads to lymphoma remission in a large number of patients when treatment occurs at an early stage(Ⅰ-Ⅱ1).Neoplasia confined to the submucosa,localized in the antral region of the stomach,and without API2-MALT1 translocation,shows a high probability of remission following H.pylori eradication.When both bacterial infection and lymphoma recur,further eradication therapy is generally effective.Radiotherapy,chemotherapy and,in selected cases,surgery are the available therapeutic options with a high success rate for those patients who fail to achieve remission,while data on immunotherapy with monoclonal antibodies (rituximab)are still scarce.The 5-year survival rate is higher than 90%,but careful,long-term follow-up is required in these patients since lymphoma recurrence has been reported in some cases. | Angelo Zullo Cesare Hassan Francesca Cristofari Francesco Perri Sergio Morini | 2010 | World Journal of Gastrointestinal Oncology2010，2，4： | 21 |
| 2 | Effects of Helicobacter pylori Eradication on Early Stage Gastric Mucosa–Associated Lymphoid Tissue Lymphoma显示文摘 | Angelo Zullo Cesare Hassan Francesca Cristofari Alessandro Andriani Vincenzo De Francesco Enzo Ierardi Silverio Tomao Manfred Stolte Sergio Morini Dino Vaira | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 3 |
| 3 | Effects of Helicobacter pylori Eradication on Early Stage Gastric Mucosa–Associated Lymphoid Tissue Lymphoma显示文摘 | Angelo Zullo Cesare Hassan Francesca Cristofari Alessandro Andriani Vincenzo De Francesco Enzo Ierardi Silverio Tomao Manfred Stolte Sergio Morini Dino Vaira | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 1 |
| 4 | Tumour necrosis factor alpha down-regulation parallels inflammatory regression in ulcerative colitis patients treated with infliximab显示文摘 | C. Hassan E. Ierardi O. Burattini V. De Francesco A. Zullo G. Stoppino C. Panella S. Morini | 2007 | Digestive and Liver Disease2007，，9： | 1 |
| 5 | Helicobacter pylori eradication with either quadruple regimen with lactoferrin or levofloxacin-based triple therapy: A multicentre study显示文摘 | A. Zullo V. De Francesco G. Scaccianoce G. Manes C. Efrati C. Hassan G. Maconi D. Piglionica C. Cannaviello C. Panella S. Morini E. Ierardi | 2007 | Digestive and Liver Disease2007，，9： | 1 |
| 6 | The impact of the Factor V Leiden mutation on pregnancy 显示文摘 | Vincezo Spins Vincezo Aleandri Francesco Morini | 2000 | Human Reproduction Updates2000，6，3： | 1 |
| 7 | Influence of the thermal energy storage on the profitability of micro-CHP systems for residential building applications显示文摘 | Enrico Saverio Barbieri Francesco Melino Mirko Morini | 2012 | Applied Energy2012，，： | 1 |
| 8 | Phenotypie and genotypie Helicobacter pylori clarithromycin resistance and therapeutic outcome: benefits and limits 显示文摘 | De Francesco V Zullo A lerardi E Giorgio F Perna F Hassan C Morini S Panella C Vaira D | 2010 | Journal of antimicrobial chemotherapy2010，65，2： | 1 |
| 9 | The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells显示文摘 | Sabrina Prudente Eleonora Morini Jay Larmon Francesco Andreozzi Natalia Di Pietro Angela Nigro Ernest V. Gervino Gaia Chiara Mannino Simonetta Bacci Thomas H. Hauser Emanuele Bellacchio Gloria Formoso Fabio Pellegrini Vittoria Proto Claudia Menzaghi Lucia | 2011 | Atherosclerosis2011，，2： | 1 |
| 10 | Relationship between p-catenin expression and epithelial cell proliferation in gastric mucosa with intestinal metaplasia显示文摘AIM: To investigate β-catenin expression in patients with intestinal metaplasia, and to look for a possible relationship between β-catenin expression and either epithelial proliferation values or Helicobacter pylori ( H pylori) infection.METHODS: Twenty patients with complete type intestinal metaplasia were studied. β-Catenin expression and epithelial cell proliferation in antral mucosa were assessed using an immunohistochemical analysis. Hpylori infectionwas detected by histology and a rapid urease test.RESULTS: Reduced β-catenin expression on the surface of metaplastic cells was detected in 13 (65%) out of 20 patients. Moreover, in eight (40%) patients intranuclear expression of β-catenin was found. When patients were analyzed according to Hpylori infection, the prevalence of both β-catenin reduction at the cell surface and its intranuclear localization did not significantly differ between infected and uninfected patients. Cell proliferation was higher in patients with intranudear β-catenin expression as compared to the remaining patients, although the difference failed to reach the statistical significance (36±8.9 vs 27.2±11.4, P = 0.06). On the contrary, a similar cell proliferation value was observed between patients with reduced expression of β-catenin on cell surface and those with a normal expression (28.1±11.8 vs26.1±8.8, P= 0.7).Hpyloriinfection significantly increased cell proliferation (33.3±10.2% vs 24.6±7.4%, respectively, P= 0.04).CONCLUSION: Both cell surface reduction and intranuclear accumulation of β-catenin were detected in intestinal metaplasia. The intranuclear localization of β-catenin increases cell proliferation. H pylori infection does not seem to play a direct role in β-catenin alterations, whilst it significantly increases cell proliferation. | Adriana Romiti Angelo Zullo Francesco Borrini Ida Sarcina Cesare Hassan Simon Winn Silverio Tomao Aldo Vecchione Sergio Morini Pietro Mingazzini | 2005 | World Journal of Gastroenterology2005，11，28： | 1 |
| 11 | Tumour Necrosis Factor Alpha in Segmental Colitis Associated with Diverticula显示文摘 | Enzo Ierardi Gianmichele Meucci Cesare Hassan Angelo Zullo Gianni Imperiali Vincenzo Francesco Carmine Panella Sergio Morini Giorgio Minoli | 2008 | Digestive Diseases and Sciences2008，，7： | 1 |
| 12 | Effects of Helicobacter pylori Eradication on Early Stage Gastric Mucosa–Associated Lymphoid Tissue Lymphoma显示文摘 | Angelo Zullo Cesare Hassan Francesca Cristofari Alessandro Andriani Vincenzo De Francesco Enzo Ierardi Silverio Tomao Manfred Stolte Sergio Morini Dino Vaira | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 1 |
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