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3篇 您的检索式:作者名="Fogel E.L."
    题名 作者 年代 出处 被引量
1原位肝移植术后成功进行内镜下吻合口狭窄治疗:胆总管狭窄的复发率Alazmi W.M. Fogel E.L. Watkins J.L. G. Lehman 程妍 2006世界核心医学期刊文摘(胃肠病学分册)2006,0,11:2
2内镜下十二指肠乳头套扎切除术治疗十二指肠乳头肿瘤Sherman S. Fogel E.L. 李翔 2005世界核心医学期刊文摘(胃肠病学分册)2005,0,4:0
3特发性胰腺炎ERCP的检查结果:囊性纤维化基因阳性及阴性患者显示文摘Abstract Abstract Background: Our series of patients with idiopathic pancreatitis (IP) found a cystic fibrosis (CF) gene abnormality in 19% compared with 3.5% in patients without pancreatitis. Objective: The objective was to determine whether the CF gene predicts more severe ERP findings. Design: This was a retrospective case-control study. Setting and Patients: From July 1998 to August 2004, CF gene analysis was performed in 819 patients with IP via Genzyme Genetics. The panel tests for 70 to 87 alleles and has a detection rate of more than 90% of the cases. Sixty-nine patients (8.4% ) who had at least one CF gene positive mutation were the study cohort. A total of 218 patients with IP and negative CF gene mutation were randomly selected from our database to be in the control group. Main Outcome Measurements: Pancreatograms were evaluated for chronic pancreatitis (CP) based on Cambridge criteria. The results of the gene analysis were not available at the time of pancreatogram interpretation. Results: Among patients positive for the CF gene, 42 (61% ) were women. The mean age at intervention was 40 years (range 14-80 years), and 48 patients (70% ) had cholecystectomy. Among patients who were negative for the CF gene, 147 (67% ) were women. The mean age at intervention was 41 years (range 9-89 years), and 125 patients (57% ) had cholecystectomy. Compared with controls, cases had higher incidence of CP (62% vs. 48% , p = 0.05), grade III CP (35% vs. 18% , p = 0.004), pseudocysts (12% vs. 4% , p = 0.036) and pancreatic strictures (20% vs. 8% , p = 0.008). Limitations: The limitations of the study were (1) retrospective design and (2) the panel used tests only for 70 to 87 alleles (of approximately, 900 CF transmembrane conductance regulator genes known). Conclusions: The mean age at intervention in both groups was similar. CP, grade III CP, pseudocysts, and pancreatic strictures were more common among patients who were CF gene positive.Alazmi W.M. Fogel E.L. Schmidt S. G.A. Lehman 张欣 2006世界核心医学期刊文摘(胃肠病学分册)2006,2,5:0
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