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| 1 | An Update on Abscisic Acid Signaling in Plants and More显示文摘 | Aleksandra Wasilewsk.a Florina Vlad Caroline Sirichandra Yulia Redko Fabien Jammes Christiane Valon Nicolas Frei dit Frey Jeffrey Leung | 2008 | Molecular Plant2008,1,2: | 46 |
| 2 | Novel mutation in the ligand-binding domain of the androgen receptor gene (1790p) associated with complete androgen insensitivity syndrome显示文摘在基因在敏感症候群(AIS ) 引起雄激素的 X 连接雄激素受体(AR ) 的变化,在 46 导致损害的胚胎的性区别, XY 基因人。在敏感(CAIS ) 的完全的雄激素生产女外部显型,而有在敏感(白族) 的部分雄激素的盒子有生殖器的各种各样的歧义。在敏感(MAIS ) 的温和雄激素被 undermasculinization 和男子女性型乳房描绘。这里,我们描述 2-month-old 46, XY 女病人,与所有 CAIS 的特征。在睾丸激素(T) 和二氢睾酮(DHT ) 合成背叛被排除。AR 基因定序在 790 上在鳕鱼的第二个库在 6 一 T 上在前显示出存在到 C 转变,核苷酸位置 2369,在 AR 蛋白质的 ligand 有约束力的域引起一个新奇错误感觉 Leu790Pro 变化。在有 CAIS 的一个女孩的一个新奇 AR 变化的鉴定在 AR 的 ligand 有约束力的领域由于错误感觉变化的重要性提供重要信息,它能在雄激素绑定能力,活跃符合构造的稳定,或和激活剂的相互作用导致功能的畸形。 | Florina Raicu Rossella Giuliani Valentina Gatta Chiara Palka Paolo Guanciali Franchi Pierluigi Lelli-Chiesa Stefano Tumini Liborio Stuppia | 2008 | Asian Journal of Andrology2008,10,4: | 4 |
| 3 | Post-operative computed tomography scan – reliable tool for quality assessment of complete mesocolic excision显示文摘BACKGROUND Quality control in colon cancer surgery is an ongoing debate ever since standardization proved to be highly efficient in improving survival in rectal cancer. Complete mesocolic excision(CME) is widely acclaimed as the new goldstandard in colon cancer resections, thus it is imperative to establish quality criteria of CME in order to make it easily understood and verified by surgeons worldwide. One simple and reproducible tool could be the measurement of arterial stumps postoperatively and a straightforward way to test its reliability is to test it in a comparative study between CME and non-CME surgery.AIM To validate arterial stump measurement as a surgical quality tool by comparing CME with conventional radical colectomies.METHODS This was a retrospective study, carried out on a prospective database. We collected data from two groups of patients, divided according to standard CME with D2 central vascular ligation(group A) and non-standardized surgery(group B). The two groups were compared with regard to the arterial stump length after right-and left-sided colectomies for colon cancer. The actual stump lengths of the ileocolic artery(ICA) and inferior mesenteric artery(IMA) were compared with their theoretical best D2 position of predicted ligation levels(D2 PLLs) for calculating the potential for improvement. Measurements on follow-up computed tomography scans were carried out by three observers. Pathological data were recorded(specimen length, lymph node yield) and correlated with stump length.RESULTS We analysed 58 colectomies. The stump lengths(mean ± SD) in group A were16.97 ± 4.77 mm for ICA and 31.70 ± 15.71 mm for IMA, whereas group B had 49.93 ± 20.29 mm for ICA and 67.24 ± 28.71 mm for IMA. Shorter lengths were obtained in group A, by a mean difference of 35.66 mm(χ~2 = 27.38, P < 0.001),which was significant for all types of colectomies. Except for a 5.85 ± 4.71 mm difference for right colectomies, all the ligations from group A significantly reached their potential height(0.26 ± 12.18 mm from D2 PLL; χ~2 = 0.005, P = 0.944).Apart from three left colectomies, group B failed to reach D2 PLL, by a mean difference of 32.14 ± 26.15 mm(χ~2 = 21.77, P < 0.001). The calculated improvement potentials were significantly shorter in group A than in group B, by a mean of 31.88 mm(χ~2= 22.13, P < 0.001). The large spread of results in group B showed that there is significant variability(P = 0.004) when compared to standard surgery. Significant correlations were found between stump length, specimen length and number of lymph nodes(P = 0.018 and P = 0.008 respectively). No statistical difference was found between observers' measurements(P = 0.866).CONCLUSION Arterial stump monitoring is a significant step in defining surgical quality, as longer stumps contain residual mesocolic tissue and correlate with major prognostic factors. | Cristian Livadaru Stefan Morarasu Tudor Cristian Frunza Florina A Ghitun Elena Florina Paiu-Spiridon Florina Sava Cristina Terinte Dan Ferariu Sorinel Lunca Gabriel Mihail Dimofte | 2019 | World Journal of Gastrointestinal Oncology2019,11,3: | 2 |
| 4 | A brief overview on synthesis and applications of graphene and graphene-based nanomaterials显示文摘Graphene is a remarkable material with great potential in many applications due to its chemical and physical properties.In this review we briefly present the recent research progress(2016-2018)in graphene and graphene-based nanomaterials synthesis and discuss the practical aspects of using the materials produced via these methods for different graphene-based applications. | Maria COROS Florina POGACEAN Lidia MAGERUSAN Crina SOCACI Stela PRUNEANU | 2019 | Frontiers of Materials Science2019,13,1: | 2 |
| 5 | Kinetics and mechanism of the reaction between maleic anhydride and fatty acid esters and the structure of the products 显示文摘 | Florina S Laure C Carlos V | 2008 | Eur J Lipid Sci Technol2008,110,: | 1 |
| 6 | Nano-structured metal-containing polymer precursors for high temperature non-oxide ceramics and ceramic fibers-syntheses,pyrolyses and properties显示文摘 | TSIRLIN A M SHCHERBAKOVA G I FLORINA E K | 2002 | Journal of the European Ceramic Society2002,22,14: | 1 |
| 7 | Effects of Growth Factors and Growth Factor - Extracellular Matrix Interactions on mouse Trophoblast Outgrowth in vitro 显示文摘 | Florina Haimovici Deborah J Anderson | 1993 | Biology of Reproduction1993,49,1: | 1 |
| 8 | Aluminium corrosion in hydrochloric acid solutions and the effect of some organic inhibitors显示文摘 | V Branzoi Florentina Golgovici Florina Branzoi | 2002 | Materials Chemistry and Physics2002,78,: | 1 |
| 9 | Square wave voltammetric detection of electroactive products resulting from electrochemical nitrate reduction in alkaline media显示文摘 | Florina Maria Cuibus Adriana Ispas Andreas Bund Petru Ilea | 2012 | Journal of Electroanalytical Chemistry2012,,: | 1 |
| 10 | En- hancing Privacy and Dynamic Federationn IdM for Consumer Cloud Computing显示文摘 | Rosa Sdnchez Florina Almenares Patricia Arias | 2012 | IEEE Transactions on Consumer Elec- tronics2012,58,1: | 1 |
| 11 | ,Characterization of bacterial community associated to biofilms of corroded oil pipelines from the southeast of Mexico显示文摘 | NERIA-GONZLEZ Isabel WANG En tao RAMREZ Florina | 2006 | Anaerobe2006,12,3: | 1 |
| 12 | Aluminium corrosion in hydrochloric acid solutions and the effect of some organic inhlbitors 显示文摘 | Branzoi V Golgovici Florentina Branzoi Florina | 2003 | Materials Chemistry and Physics2003,78,1: | 1 |
| 13 | The corrosion protection afforded by rare earth conversion coatings applied to magnesium显示文摘 | AMY L Rudd CARMEL Breslin B FLORINA Mansfeld | 2000 | Corrosion Science2000,42,: | 1 |
| 14 | Effects of growth factor-extracellular matrix interactions on mouse trophoblast outgrowth in vitro显示文摘 | Haimovici Florina Anderson DJ | 1993 | Biol Reprod1993,49,: | 1 |
| 15 | Trust management for multimedia P2P applications in autonomic networking 显示文摘 | Florina Almendrez Andres Marin | 2011 | Ad HocNetworks2011,9,4: | 1 |
| 16 | Male infertility: role of genetic background显示文摘 | Alberto Ferlin Florina Raicu Valentina Gatta Daniela Zuccarello Giandomenico Palka Carlo Foresta | 2007 | Reproductive BioMedicine Online2007,,6: | 1 |
| 17 | Ceramic foam monoliths as catalyst carriers 1 adiustment and description of the morphology显示文摘 | Florina C Buciuman Bettina Kraushaar-Czametzki | 2003 | Ind Eng Chem Res2003,42,: | 1 |
| 18 | Two-stage distributed generation optimal sizing with clustering-based node selection显示文摘 | Florina Rotaru Gianfranco Chicco Gheorghe Grigoras Gheorghe Cartina | 2012 | International Journal of Electrical Power and Energy Systems2012,,1: | 1 |
| 19 | Racial disparities in immune-related adverse events of immune checkpoint inhibitors and association with survival based on clinical and biochemical responses显示文摘BACKGROUND Immune checkpoint inhibitors(ICPi)cause various immune-related adverse events(irAE)with thyroid dysfunction as a commonly reported abnormality.There is increasing evidence showing positive association with development of irAE and survival.However,prior trials with ICPi had underrepresentation of minorities with<5%African Americans.AIM To evaluate the association between development of irAE and survival outcomes among a racially diverse patient population.METHODS Data on patients with stage IV solid malignancies treated with programmed cell death-protein 1/programmed death ligand 1 blockers between January 2013 and December 2018 across MedStar Georgetown Cancer Institute facilities were retrospectively reviewed.Patients treated with cytotoxic T-lymphocyte-associated protein 4 inhibitors were excluded.Progression free survival(PFS)and overall survival(OS)were primary endpoints and were calculated using Kaplan-Meier methods and Wilcoxon rank sum test for comparison.RESULTS Out of 293 patients who met eligibility criteria,91 pts(31%)had any grade irAE;most common AE were endocrine(40.7%)specifically TSH elevation,dermatological(23.1%)and rheumatologic(18.7%).Proportion of irAE was significantly higher in Caucasians vs African Americans(60.4%vs 30.8%),in patients with low programmed death ligand 1,lower LDH,older age,and those who had more treatment cycles with ICPi.Rate of progression was lower in patients with irAE(30.8%vs 46.0%,P=0.0140).Median PFS(5.8 vs 3.0 mo,P=0.0204)and OS(17.1 vs 7.2 mo,P<0.0001)were higher with irAE.Statistically significant difference in OS(17.1 vs 8.6 mo,P=0.0002)but not in PFS(5.8 vs 3.3 mo,P=0.0545)was noted with endocrine irAE.No differences in survival were observed among other commonly reported irAE.Differences in survival among subgroups of patients with irAE are described.CONCLUSION Development of irAE positively correlated with improved PFS and OS as reported in previous studies.To our knowledge,this is the first study observing differences in OS favoring endocrine AE and Caucasian race.These factors may be potential surrogate markers of prognosis pending replication of these results in large-scale studies. | Monica Peravali Cristiane Gomes-Lima Eshetu Tefera Mairead Baker Mamta Sherchan Saira Farid Kenneth Burman Florina Constantinescu Irina Veytsman | 2021 | World Journal of Clinical Oncology2021,12,2: | 1 |
| 20 | Protection of Personal Data-actual and Proposed Issues显示文摘 | Florina Mariana Olteanu Mihaela Olteanu | 2012 | EIRP Proceedings2012,7,1: | 1 |