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| 1 | The importance of avoiding unnecessary right ventricular pacing in clinical practice显示文摘Symptomatic bradycardia is effectively treated with the implantation of a cardiac pacemaker. Although a highly successful therapy, during recent years there has been a focus on the negative effects associated with longterm pacing of the apex of the right ventricle(RV). It has been shown in both experimental and clinical studies that RV pacing leads to ventricular dyssynchrony, similar to that of left bundle branch block, with subsequent detrimental effects on cardiac structure and function, and in some cases adverse clinical outcomes such as atrial fibrillation, heart failure and death. There is substantial evidence that patients with reduced left ventricular function(LVEF) are at particular high risk of suffering the detrimental clinical effects of long-term RV pacing. The evidence is, however, incomplete, coming largely from subanalyses of pacemaker and implantable cardiac defibrillator studies. In this group of patients with reduced LVEF and an expected high amount of RV pacing, biventricular pacing(cardiac resynchronization therapy) devices can prevent the negative effects of RV pacing and reduce ventricular dyssynchrony. Therefore, cardiac resynchronization therapy has emerged as an attractive option with promising results and more clinical studies are underway. Furthermore, specific pacemaker algorithms, which minimize RV pacing, can also reduce the negative effects of RV stimulation on cardiac function and may prevent clinical deterioration. | Finn Akerstrm Miguel A Arias Marta Pachón Jesús Jiménez-López Alberto Puchol Justo Juliá-Calvo | 2013 | World Journal of Cardiology2013，5，11： | 3 |
| 2 | Subcutaneous implantable defibrillator: State-of-the art 2013显示文摘The subcutaneous implantable cardioverter-defibrillator(S-ICD)has recently been approved for commercial use in Europe,New Zealand and the United States.It is comprised of a pulse generator,placed subcutaneously in a left lateral position,and a parasternal subcutaneous lead-electrode with two sensing electrodes separated by a shocking coil.Being an entirely subcutaneous system it avoids important periprocedural and long-term complications associated with transvenous implantable cardioverter-defibrillator(TV-ICD)systems as well as the need for fluoroscopy during implant surgery.Suitable candidates include pediatric patients with congenital heart disease that limits intracavitary lead placements,those with obstructed venous access,chronic indwelling catheters or high infection risk,as well as young patients with electrical heart disease(e.g.,Brugada Syndrome,long QT syndrome,and hypertrophic cardiomyopathy).Nevertheless,given the absence of intracavitary leads,the S-ICD is unable to offer pacing(apart from shortterm post-shock pacing).It is therefore not suitable in patients with an indication for antibradycardia pacing or cardiac resynchronization therapy,or with a history of repetitive monomorphic ventricular tachycardia that would benefit from antitachycardia pacing.Current data from initial clinical studies and post-commercialization'real-life'case series,including over 700 patients,have so far been promising and shown that the S-ICD successfully converts induced and spontaneous ventricular tachycardia/ventricular fibrillation episodes with associated complication and inappropriate shock rates similar to that of TV-ICDs.Furthermore,by using far-field electrograms better tachyarrhythmia discrimination when compared to TV-ICDs has been reported.Future results from ongoing clinical studies will determine the S-ICD system’s long-term performance,and better define suitable patient profiles. | Finn Akerstrm Miguel A Arias Marta Pachón Alberto Puchol Jesús Jiménez-Lópezl | 2013 | World Journal of Cardiology2013，5，9： | 2 |
| 3 | Pathology of drug-elu-ting stents in humans:delayed healing and late thrombotic risk显示文摘 | Finn AV Farb A | 2006 | J Am CoIl Cardiol2006，48，1： | 1 |
| 4 | Sugar analysis of glycoproteins and glycolipids after methanolysis by high-performance liquid chromatography with pulsed amperometric detection 显示文摘 | Lampio A Finne J | 1991 | Anal Biochem1991，197，1： | 1 |
| 5 | L-lactide macromonomer synthesis initiated by new cyclic tinalkoxides functionalized for brushlike structures 显示文摘 | Ryner M Finne A Albertsson A C | 2001 | Macromolecules2001，34，21： | 1 |
| 6 | The MAFT architecture for distributed fault - tolerance 显示文摘 | Kieckhafer R M Walter C J Finn A M | 1988 | IEEE Trans Computers1988，37，4： | 1 |
| 7 | Cu(])-aza(bisoxazoline)-catalyzed asymmetric benzoylations显示文摘 | GISSIBL A FINN M G REISER O | 2005 | Organic Letters2005，7，12： | 1 |
| 8 | Human papillomavirus infection and primary fallopian tube carcinoma:a seroepidemiological study显示文摘 | Riska A Finne P Koskela P | 2007 | B JOG2007，114，4： | 1 |
| 9 | Pathology of drug-eluting stents in humans:Delayed healing and late thrombotic risk显示文摘 | Joner M Finn AV Farb A | 2006 | J Am Coll Cardiol2006，48，1： | 1 |
| 10 | Pathology of drug-eluting stents in humans : delayed healing and late thrombotic risk显示文摘 | Joner M Finn AV Farb A | 2006 | J Am Coll Cardiol2006，48，： | 1 |
| 11 | Increased dopaminergic and 5- hydroxytryptaminergic activities in male rat brain following long- term treatment with anabolic androgenic steroids 显示文摘 | Thiblin I Finn A Ross S B | 1999 | Br J Phar- macol1999，126，6： | 1 |
| 12 | Vertebrate vitellogenin gene duplication in relation to the ' 3R hypothesis' : correlation to the pelagic egg and the oceanic radiation of teleosts 显示文摘 | FINN R N KRISTOFFERSEN B A | 2007 | PLuS ONE2007，2，1： | 1 |
| 13 | Feasibility and long- term stability of surgically assisted rapid maxillary expansion with lateral osteotomy显示文摘 | Anttila A Finne K Keski-Nisula K | 2004 | Eur J Orthod2004，26，4： | 1 |
| 14 | Fish larval nutrition: a review of recent advances in the roles of amino acids显示文摘 | Thorsen A Finn R N | 1999 | Aquuaculture1999，177，： | 1 |
| 15 | HPV prevention: waiting for screening services显示文摘 | Finn A | 2010 | Lanvet2010，375，9727： | 1 |
| 16 | Chemokine receptors and their role in in-flammation and infectious deisease 显示文摘 | Murdoch C Finn A | 2000 | Blood2000，95，10： | 1 |
| 17 | Pathology of drug-eluting stents in humans : delayed healing and late thrombotic risk 显示文摘 | Joner M Finn AV Farb A | 2006 | J Am Coil Cardiol2006，48，： | 1 |
| 18 | Management of young goats during prolonged fasting affects carcass characteristics but not pre-slaughter live weight or cortisol显示文摘 | Greenwood P L Finn J A May T J Nicholls P J | | 0，，06： | 1 |
| 19 | Pathology of drug - eluting stents inhumans: delayed healing and late thrombotic risk显示文摘 | Joner M Finn AV Farb A | 2006 | 48*1932006，，： | 1 |
| 20 | Phosphatidylinositol 3-kinase and mTOR mediate lipopolysaccharide-stimulated nitric oxide production in macrophages via interferon-beta显示文摘 | Weinstein S L Finn A J Dave S H | 2000 | J Leukoc Biol2000，67，： | 1 |
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