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293篇 您的检索式:作者名="Finegold"
    题名 作者 年代 出处 被引量
1Wilson disease:Histopathological correlations with treatment on follow-up liver biopsies显示文摘AIM:To investigate the progression of hepatic histopathology in serial liver biopsies from Wilson disease(WD)patients.METHODS:We report a group of 12 WD patients treated with zinc and/or penicillamine who underwent multiple follow-up liver biopsies.Demographic,clinical and laboratory data were gathered and all patients underwent an initial biopsy and at least one repeat biopsy.RESULTS:Time to repeat biopsy ranged from 2 to 12 years.Six patients(non-progressors)showed stable hepatic histology or improvement.In one case,we observed improvement of fibrosis from stage 2 to 0.Six patients(progressors)had worsening of fibrosis.There was no significant correlation between the histological findings and serum aminotransferases or copper me-tabolism parameters.The hepatic copper concentration reached normal levels in only two patients:one from the non-progressors and one from the progressors group.The estimated rate of progression of hepatic fibrosis in the entire group was 0 units per year in the time frame between the first and the second liver biopsy(4 years),and 0.25 between the second and the third(3 years).In the progressors group,the rate of progression of liver fibrosis was estimated at 0.11 fibrosis units per year between the first and second biopsy and,0.6 fibrosis units between the second and third biopsy.CONCLUSION:The inability of clinical tools to detect fibrosis progression in WD suggests that a liver biopsy with hepatic copper quantification every 3 years should be considered.Sandy Cope-Yokoyama Milton J Finegold Giacomo Carlo Sturniolo Kyoungmi Kim Claudia Mescoli Massimo Rugge Valentina Medici 2010World Journal of Gastroenterology2010,16,12:10
2Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis显示文摘Anakk Sayeepriyadarshini Watanabe Mitsuhiro Ochsner Scott A McKenna Neil J Finegold Milton J Moore David D 2011Journal of Clinical Investigation2011,,1:2
3Diagnostic and therapeutic role of endoscopic retrograde cholangiopancreatography in biliary rhabdomyosarcoma显示文摘Biliary rhabdomyosarcoma (BRMS) is an uncommon childhood malignancy which has been managed surgically. We present a case of a 3-year-old boy with BRMS, in whom endoscopic retrograde cholangiopancreatography (ERCP) was successfully used both diagnostically and therapeutically, thus obviating the need for surgery and its attendant risks of morbidity and mortality. We conclude that ERCP is an effective alternative to surgery for BRMS in some patients.Ryan W Himes Isaac Raijman Milton J Finegold Heidi V Russell Douglas S Fishman 2008World Journal of Gastroenterology2008,14,30:2
4Group A rotavir-us infection and age-dependent diarrheal disease in rats:a new animal model to study the pathophysiology of rotavirus infection显示文摘Ciarlet M Conner M E Finegold M J 2002J Virol2002,76,1:1
5Medium chain acyl-CoA dehydrogenase deficiency in pennsylvania:neonatal screening shows high incidence and unexpected mutation frequencies显示文摘Ziadeh R Hoffman EP Finegold DN 1995Pediatr Res1995,37,5:1
6Anaerobic infection显示文摘Finegold SM 1980Surg Clin North Am1980,157,:1
7Deconjugation of bile acids by intestinal bacteria:a review of literature and additional studies显示文摘SHIMADA K BRICKNELL K S FINEGOLD S M 0,,:1
8Effect of β-lactamase inhibitors on the activities of variousβ-lactam agents against anaerobic bacteria显示文摘Wexler HM Molitoris E Finegold SM 1991Antimicrob Agents Chemother1991,35,6:1
9The severe and moderate phenotypes of heritable Mac-1,LAK-1deficiency; The quantitative definition and relation to leukocyte dysfunction and clinical feature显示文摘Anderson D C Schmalsteig F C Finegold M J 1985J Infect Dis1985,152,4:1
10Mutations in Bile Salt Export Pump ( ABCB11 ) in Two Children with Progressive Familial Intrahepatic Cholestasis and Cholangiocarcinoma显示文摘A.O. Scheimann S.S. Strautnieks A.S. Knisely J.A. Byrne R.J. Thompson M.J. Finegold 2007The Journal of Pediatrics2007,,5:1
11What proportion of symptomatic side effects in patients taking statins are genuinely caused by the drug? Systematic review of randomized placebocontrolled trials to aid individual patient choice显示文摘Finegold JA Manisty CH Goldacre B 2014Eur J Prev Cardiol2014,21,:1
12Impaired energy homeostasis in C/EBP alpha knockout mice 显示文摘Wang N D Finegold M J Bradley A 1995Science1995,269,:1
13Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice 显示文摘Lee TH Finegold MJ Shen RF 1990J Virol1990,64,2:1
14Prostate cancer in a transgenic mouse 显示文摘GREENBERG N M DEMAYO F FINEGOLD M J 1995Proc Natl Acad Sci USA1995,92,:1
15Development of T- cell lymphomas in Emu-IEX-1 mice 显示文摘Zhang Y Finegold M J Porteu F 2003Oncogene2003,22,44:1
16Anaerobic pleuropulmonary infections 显示文摘Bartlett JG Finegold SM 1972Medicine (Baltimore)1972,51,6:1
17Photonic crystal glucose- Sensing material for noninvasive monitoring of glucose in tear fluid 显示文摘Alexeev V L Das S Finegold D N 2004Clinical Chemistry2004,50,12:1
18A paracrine paradigm for in vivo gene therapy in the central nervous system:treatment of chronic pain显示文摘Finegold AA Mannes AJ Iadarola MJ 1999Hum Gene Ther1999,10,7:1
192014 global geo- graphic analysis of mortality from ischaemic heart disease by country, age and income: statistics from World Health Or- ganisation and United Nations 显示文摘Nowbar AN Howard JP Finegold JA 2014Int J Cardiol2014,174,2:1
20Impaired energy homeostasis in C/EBPα knockout mice显示文摘Wang ND Finegold MJ Bradley A 1995Science1995,269,16:1
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