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| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | Net requirements of calcium, magnesium, sodium, phos- phorus, and potassium for growth of Nellore X Red Angus bulls, steers, and heifers显示文摘 | Chizzotti M L Filho S D C V Tedeschi L O | 2009 | Livestock Science2009，124，1： | 1 |
| 3 | On systems of elliptic equations involving subcritical or critical Sobolev exponents显示文摘 | Alves C O Filho D C de M Souto M A S | 2000 | Nonlinear Analysis2000，42，： | 1 |
| 4 | Targeting key alteration minerals in epithermal deposits in Patagonia, Argentina, using ASTER imagery and principal component analysis显示文摘 | Crosta A P Souza Filho C R D E | 2003 | INT J Remote Sensing2003，24，21： | 1 |
| 5 | An integrated approach to power system reliability assessment 显示文摘 | 2 M T Schiling M B D C Filho A M L D Silvaetc | 1995 | Electrical Power1995，17，6： | 1 |
| 6 | Copper resistance of biofilm cells of the plant pathogen Xylella fastict- iosa 显示文摘 | Rodrigues C M Takita M A Coletta Filho H D | 2008 | Appl Microbiol Biotechnol2008，77，5： | 1 |
| 7 | Ecodesign methods focused on remanufacturing 显示文摘 | PIGOSSO D C A ZANETTE E T FILHO A G | 2010 | Journal ofCleanerProduction2010，18，1： | 1 |
| 8 | Auto- matic detection of small lung nodules in 3D CT data using Gaussian mixture models, Tsallis entropy and SVM 显示文摘 | SANTOS A M FILHO A O D C SILVA A C | 2014 | Engineering applications of artificial intelligence2014，，36： | 1 |
| 9 | Less critical procedure for silicon wafer using diluted HF dip and boiling in isopropyl alcohol as final steps显示文摘 | Filho G D S Hasenack C M Salary L C | 1995 | J Electrochem Soc1995，142，3： | 1 |
| 10 | Lower uterine segment thickness measure-ment in pregnant women with previous Cesarean sec-tion:reliability analysis using two and three-dimen-sional transabdominal and transvaginal ultrasound显示文摘 | Martins W P Barra D A Gallarreta F M'Nastri C 0 Filho F M | 2009 | Ultrasound Obstet Gynecol2009，33，： | 1 |
| 11 | Influence of particle size and specific surface area on the pozzolanic activity of residual rice husk ash 显示文摘 | CORDEIRO G C FILHO R D T TAVARES L M | 2011 | Cem Concr C ompos2011，33，： | 1 |
| 12 | Adaptive fuzzy controller for efficiency optimization of induction motors 显示文摘 | Souza D A Filho W C P Sousa G C D | 2007 | IEEE Transactions on Industrial Electronics2007，54，4： | 1 |
| 13 | Introduction to organic thin film transistors and design of n-channel organic semiconductors 显示文摘 | NEWMAN C R FRISBIE C D DA SILVA FILHO D A | 2004 | Chemistry of Materials2004，16，23： | 1 |
| 14 | Organogenesis and transient genetic transformation of the hybrid Eucalyptus grandis×Eucalyptus urophylla显示文摘 | Alcantara G B D Bespalhok Filho J C Quoirin M | 2011 | Scientia Agricola2011，68，： | 1 |
| 15 | ! Embedded system integrated into a wireless sensor network for online dynamic torque and efficiency monitoring in induction motors 显示文摘 | FILHO A C L GOMES R D ADISSI M O | 2012 | IEEE/ASME Transactions on Mechatronics2012，17，3： | 1 |
| 16 | Effect of the thermal annealing on the electrical and physical properties of SiC thin films produced by RF magnetron sputtering显示文摘 | RAJAB S M OLIVEIRA I C MASSI M MACIEL H S DOS SANTOS FILHO S G MANSANO R D | 2006 | Thin Solid Films2006，515，： | 1 |
| 17 | Evaluation of the bioremoval of Cr (VI) and TOC in biofilters under continuous operation using response surface methodology 显示文摘 | Leles D M Lemos D A Filho U C | 2012 | Biodegradation2012，23，44： | 1 |
| 18 | On systems of elliptic equations involving subcritical or critical Sobolev exponents 显示文摘 | Alves C O de Morais Filho D C Souto M A S | 2000 | Nonlinear Analysis2000，42，： | 1 |
| 19 | Effect of replacing alfalfa si- lage with high moisture corn on mminal protein syn- thesis estimated from excretion of total purine deriva- tives显示文摘 | VALADARES R F D BRODERICK G A VALADA- RES FILHO S C | 1999 | Journal of Dairy Science1999，82，12： | 1 |
| 20 | Consolidation of partially amorphous alumiNum-alloy powders by severe plastic deforrnation显示文摘 | BOTTA FILHO W Jz FOGAGNOLO J B RODRIGUES C A D | 2004 | Materials Science and Engineering A2004，，： | 1 |
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